Results 41 to 50 of about 37,428 (161)

Cycloferon as a Means for Prevention, Treatment, and Control of COVID-19: Multidisciplinary and Comparative Historical Aspects

open access: yesАнтибиотики и Химиотерапия, 2022
The study of coronaviruses, including those capable of causing life-threatening diseases, continued for many decades. So did the study of interferons, as well as acridine acetic acid, which is a powerful interferon inducer.
P. V. MAZIN   +4 more
doaj   +1 more source

A pilot study of temsirolimus and body composition. [PDF]

open access: yes, 2013
PurposeBody weight and composition play a role in cancer etiology, prognosis, and treatment response. Therefore, we analyzed the weight, body composition changes, and outcome in patients treated with temsirolimus, an mTor inhibitor that has weight loss ...
Janku, Filip   +6 more
core   +2 more sources

ACTIVATION OF SYNTHESIS OF ENDOGENOUS INTERFERON (REVIEW)

open access: yesРазработка и регистрация лекарственных средств, 2019
The review is dedicated to the description of interferon inducers - new generation drugs created by Russian scientists as a result of the screening of thousands of high- and low-molecular synthetic and natural compounds.
V. V. Poloskov, F. I. Ershov
doaj  

Modulation of the host Th1 immune response in pigeon protozoal encephalitis caused by Sarcocystis calchasi [PDF]

open access: yes, 2013
Pigeon protozoal encephalitis (PPE) is an emerging central-nervous disease of domestic pigeons (Columba livia f. domestica) reported in Germany and the United States.
Gruber, Achim D.   +5 more
core   +3 more sources

The use of innovative domestic interferon inducer for the prevention and treatment of acute respiratory viral infections in children

open access: yesМедицинский совет, 2016
The article presents data on the place of the modern endogenous interferon inducers in the treatment and prevention of influenza and ARVI in children and the mechanisms of action.
Y. L. Mizernitskiy
doaj   +1 more source

Truncation of the NS1 protein converts a low pathogenic avian influenza virus into a strong interferon inducer in duck cells [PDF]

open access: yes, 2010
The NS1 protein of influenza A viruses is known as a nonessential virulence factor inhibiting type I interferon (IFN) production in mammals and in chicken cells. Whether NS1 inhibits the induction of type I IFNs in duck cells is currently unknown.
Guérin, Jean-Luc   +3 more
core   +1 more source

THEORETICAL AND APPLIED ASPECTS OF THE INTERFERON SYSTEM: TO THE 60TH ANNIVERSARY OF THE DISCOVERY OF INTERFERONS

open access: yesВопросы вирусологии, 2018
The review contains a brief analysis of the 60-year history of the discovery, study and medical application of interferons, a new group of remarkable proteins that have found wide medical application in the therapy of virological, oncological ...
F. I. Ershov, A. N. Narovlyansky
doaj   +1 more source

In vitro CRISPR screening uncovers CRTC3 as a regulator of IFN-γ-induced ferroptosis of hepatocellular carcinoma

open access: yesCell Death Discovery, 2023
Interferon-gamma (IFN-γ) exerts anti-tumor effects by inducing ferroptosis. Based on CRISPR/Cas9 knockout screening targeting genome-wide protein encoding genes in HepG2 and SK-Hep-1 cell lines, we found that cAMP response element-binding protein (CREB ...
Li Li   +10 more
doaj   +1 more source

Вугрова хвороба:сучасні можливості лікування [PDF]

open access: yes, 2010
Изучена эффективность использования макролидных антибиотиков и индукторов интерферона в комплексном лечении больных папуло-пустулезной формой угревой болезни. Установлено их позитивное влияние на клиническое течение заболевания, качество жизни пациентов,
Бєлай, І.М.   +4 more
core  

Use of immunomodulators in infectious diseases of domestic animals/
Uso de imunomoduladores nas enfermidades infecciosas dos animais domésticos

open access: yesSemina: Ciências Agrárias, 2007
Immunomodulators are substances that act in the immune system providing, increase of the organic answer against microorganisms, including virus, bacteria and protozoa, by inducing the production of interferon and its inducers.
Jane Megid, Camila Michele Appolinário
doaj   +1 more source

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