Results 121 to 130 of about 223,138 (357)

NADPH Oxidase and Guanylate Binding Protein 5 Restrict Survival of Avirulent Type III Strains of Toxoplasma gondii in Naive Macrophages

mBio, 2018
Phagocytic cells are the first line of innate defense against intracellular pathogens, and yet Toxoplasma gondii is renowned for its ability to survive in macrophages, although this paradigm is based on virulent type I parasites.
Sumit K. Matta, Kelley Patten, Quiling Wang, Bae-Hoon Kim, John D. MacMicking, L. David Sibley   +5 more
doaj   +1 more source

Aggressive primary testicular diffuse large B-cell lymphoma, not otherwise specified with expression of interferon-γ and its receptors [PDF]

, 2012
Shoko Nakayama‐Ichiyama, Taiji Yokote, Yuji Hirata, Kazuki Iwaki, Uta Nishiwaki, Takuji Miyoshi, Yuki Masuda, Toshikazu Akioka, Motomu Tsuji, Toshiaki Hanafusa   +9 more
openalex   +1 more source

Marked Long‐term Improvement in Lung Function in Melanoma Differentiation‐associated Protein 5 (MDA5) Antibody Positive Dermatomyositis Patients: Experience of a Single Center Longitudinal Cohort in North America

Arthritis Care &Research, Accepted Article.
Objective The objective of this study was to describe the longitudinal disease course and pulmonary outcomes of North American patients with melanoma differentiation‐associated gene 5 antibody (MDA5 ab) associated dermatomyositis (DM). Methods Thirty patients with MDA5 ab DM were identified in a single center longitudinal cohort of 352 patients with ...
Jenice X Cheah, Sangmee S Bae, Tiffany De Leon, Yuna Lee, Rong Guo, David Elashoff, Jennifer Wang, Ani Shahbazian, Christina Charles‐Schoeman   +8 more
wiley   +1 more source

Host‐Directed Biomaterials for Combatting Bloodstream Infections: From Macrocyclic Peptides to Immune‐Activating Cell Backpacks

Advanced Functional Materials, EarlyView.
Bloodstream infections (BSI) are one of the leading causes of mortality and morbidity in both civilian and military populations. This paper summarizes recent progress in novel treatment strategies to manage BSI arising from both bacterial and fungal pathogens using molecules, particles, and materials to elicit host‐directed immunity.
Thomas Thomou, Jagadish Krishnappa, Justin B. Schaal, Prasad Tongaonkar, Dat Q. Tran, Wenchao Gu, Yung‐Fu Chang, Michael E. Selsted, Shaoyi Jiang, Samir Mitragotri, Michael Super, Christopher J. Bettinger   +11 more
wiley   +1 more source

Author response: Reactive oxygen species oxidize STING and suppress interferon production

, 2020
Lili Tao, Andrew Lemoff, Guoxun Wang, Christina Zarek, Alexandria Lowe, Nan Yan, Tiffany A. Reese   +6 more
openalex   +1 more source

The network interplay of interferon and toll-like receptor signaling pathways in the anti-Candida immune response

, 2021
Ranieri Coelho Salgado, Dennyson Leandro M. Fonseca, Alexandre H. C. Marques, Sarah Maria da Silva Napoleão, Tábata Takahashi França, Karen Tiemi Akashi, Caroline Aliane de Souza Prado, G. Baiocchi, Desirée Rodrigues Plaça, Gabriel Jansen-Marques, Igor Salerno Filgueiras, Roberta De Vito, Paula Paccielli Freire, Gustavo Cabral de Miranda, Niels Olsen Saraiva Câmara, Vera Lúcia Garcia Calich, Hans D. Ochs, Lena F. Schimke, Igor Jurišica, Antônio Condino‐Neto, Otávio Cabral-Marques   +20 more
openalex   +1 more source

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

Advanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj, Hannah S. Newton, Jian Wang, Laxmi Pandey, Yelixza I. Avilla, Phong Nguyen, Morgan Chandler, Justin Halman, Yasmine Radwan, Stephanie Smith, Elijah Edmondson, Simone Difilippantonio, Chelsea Sanders, Bao Tran, Yongmei Zhao, Shaojun Xie, Edward Cedrone, Barry W. Neun, Meni Wanunu, Nikolay V. Dokholyan, Marina A. Dobrovolskaia, Kirill A. Afonin   +21 more
wiley   +1 more source

Efeito do interferon-gamma sobre defeitos de "splicing" que levam à doença granulomatosa crônica ligada ao cromossomo X. [PDF]

, 2009
Josias Brito Frazão
openalex   +1 more source

CTNI-33. CSNO2012001 STUDY: A PHASE III TRIAL ON ADJUVANT TEMOZOLOMIDE CHEMOTHERAPY WITH OR WITHOUT INTERFERON-ALPHA IN NEWLY DIAGNOSED HIGH-GRADE GLIOMAS [PDF]

, 2022
Zhongping Chen, Chengcheng Guo, JianGen Chen   +2 more
openalex   +1 more source

Region‐to‐Region Unidirectional Connection In Vitro Brain Model for Studying Directional Propagation of Neuropathologies

Advanced Functional Materials, EarlyView.
A unidirectional cerebral organoid–organoid neural circuit is established using a microfluidic platform, enabling controlled directional propagation of electrical signals, neuroinflammatory cues, and neurodegenerative disease–related proteins between spatially separated organoids.
Kyeong Seob Hwang, Hui‐Wen Liu, Hyogeun Shin, Hyun Wook Kang, Minjin Kang, Jongbaeg Kim, Il‐Joo Cho, Nakwon Choi, Seok Chung, Hong Nam Kim   +9 more
wiley   +1 more source