Results 141 to 150 of about 214,014 (308)

Local and Systemic Protection by Synthetic Polyanionic Interferon Inducers in mice against Intranasal Vesicular Stomatitis Virus

, 1969
Erik De Clercq, T. C. Merigan
openalex   +1 more source

Role of Interferon in the Propagation of MM Virus in L Cells [PDF]

, 1969
David Giron
openalex   +1 more source

RIG‐I‐Inducing Small Molecules Potently Inhibit HMA‐Resistant AML Through Igniting the Overloaded dsRNA Arsenal

Advanced Science, EarlyView.
This study reveals a novel mechanism of resistance to DNA hypomethylating agents (HMAs) in acute myeloid leukemia (AML), and identifies all‐trans retinoic acid (ATRA) and tamibarotene (TAM) as potent agents that overcome HMA resistance by reactivating the interferon anticancer immune response. The findings offer promising therapeutic strategies for HMA‐
Xueqin Chen, Jiaqi Wu, Yuntong Li, Jiayu Huang, Xiangqin Weng, Jiale Wu, Shujun Xiao, Huaxin Song, Zhengyuan Wang, Ni Yan, Fangfang Shi, Derun Zheng, Kai Tan, Hesong Zhang, Jingyi Cui, Wen Wu, Wei Wu, Sujiang Zhang, Min Lu   +18 more
wiley   +1 more source

The cGAS-STING pathway: a dual regulator of immune response in cancer and therapeutic implications. [PDF]

J Transl Med
Huang Z, Zhu J, Zhou YL, Shi J.
europepmc   +1 more source

Gene with Quantitative Effect on Circulating Interferon Induced by Newcastle Disease Virus

, 1969
Edward De Maeyer, Jaqueline De Maeyer‐Guignard   +1 more
openalex   +1 more source

Relationship Between Viremia and Interferon Production of Japanese Encephalitis Virus [PDF]

, 1969
Hinae Rokutanda
openalex   +1 more source

Hypoglycemia Induces Diabetic Macrovascular Endothelial Dysfunction via Endothelial Cell PANoptosis, Macrophage Polarization, and VSMC Fibrosis

Advanced Science, EarlyView.
This study investigates hypoglycemia‐induced diabetic macrovascular endothelial dysfunction. It reveals that hypoglycemia triggers ZBP1‐dependent PANoptosis of endothelial cells, proinflammatory polarization of macrophages, and fibrosis of vascular smooth muscle cells (VSMCs) in diabetic mice.
Deyu Zuo, Yuce Peng, Guozhi Zhao, Zhesheng Cheng, Minghao Luo, Dingyi Lv, Shuting Chang, Na Li, Yanyao Huang, Xunjia Li, An He   +10 more
wiley   +1 more source

Phyto-derived interferons: a promising frontier in antiviral therapy development. [PDF]

EXCLI J
Venkidasamy B, Balaraman AK, Thiruvengadam M.   +2 more
europepmc   +1 more source

INHIBITION OF INTERFERON PRODUCTION BY CHLOROQUINE DIPHOSPHATE

, 1968
S. Kohno, Masayoshi Kohase, Masaru Suganuma   +2 more
openalex   +2 more sources

MCT1‐mediated Lactate Shuttle to Mitochondria Governs Macrophage Polarization and Modulates Glucose Homeostasis by Affecting β Cells

Advanced Science, EarlyView.
This study demonstrates that the transport of lactate to the mitochondria is of critical importance in determining the functions of macrophages by altering mitochondrial respiration. In macrophages, this lactate transport mechanism regulates glucose homeostasis by influencing the functions of insulin‐secreting cells in the pancreatic islets.
Lingling Chen, Yijun Lin, Xinyu Zhu, Shixuan Zhuo, Zixuan Li, Cheng Guo, Xiaoyi Ye, Jinzhu Chen, Shuying Wang, Yan Chen   +9 more
wiley   +1 more source