Results 211 to 220 of about 136,515 (265)
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A clinical trial with an interim analysis
Statistics in Medicine, 1986AbstractWe consider a fixed‐sample parallel‐group clinical trial with an interim analysis that tests Ho: μx = μy against H1: μx < μy. If we do not reject at the interim analysis, then the probability of making a type I error by rejecting Ho in favour of H2: μx > μy and the power at the final analysis are not appreciably affected by performing the
P Y, Chi, D R, Bristol, J V, Castellana
exaly +4 more sources
2021
New advances have taken place in the medical environment, medical device industry, and in vitro diagnosis field from 2019 to 2020. For the whole industry and all Chinese professionals, these changes are both difficulties and possibilities. This article performs an industry analysis and presents the situation analysis of in vitro diagnosis industry.
Haibo Song +4 more
openaire +1 more source
New advances have taken place in the medical environment, medical device industry, and in vitro diagnosis field from 2019 to 2020. For the whole industry and all Chinese professionals, these changes are both difficulties and possibilities. This article performs an industry analysis and presents the situation analysis of in vitro diagnosis industry.
Haibo Song +4 more
openaire +1 more source
Interim Analysis and Sample Size Reassessment
Biometrics, 2000Summary. This article deals with sample size reassessment for adaptive two‐stage designs based on conditional power arguments utilizing the variability observed at the first stage. Fisher's product test for the p‐values from the disjoint samples at the two stages is considered in detail for the comparison of the means of two normal populations.
Posch, Martin, Bauer, Peter
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An interim analysis of recruitment to the COLOFOL trial
Colorectal Disease, 2009AbstractObjective To analyse the ongoing process of recruiting patients into a multicenter randomized trial on follow‐up after curative surgery for colorectal cancer. The trial is registered in Clinical Trials Registration.Method Prospective registration of all operated patients as well as inclusions (curative resection, stage II or III disease, ≤ 75
Wille-Jørgensen, Peer +7 more
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Multiple comparisons in interim analysis
Journal of Statistical Planning and Inference, 1999zbMATH Open Web Interface contents unavailable due to conflicting licenses.
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Interim futility analysis with intermediate endpoints
Clinical Trials, 2008Background Interim analysis of Phase III trials typically includes testing for both efficacy and futility. Futility testing is commonly performed on the primary outcome at very low levels (e.g., one-sided α=0.0025) at one or two times before final analysis.
Bryan, Goldman +2 more
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