Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Komputasi Aliran Daya Optimal Sistem Tenaga Skala Besar dengan Metode Primal Dual Interior Point
This paper focuses on the use of Primal Dual Interior Point method in the analysis of optimal power flow. Optimal power flow analysis with Primal Dual Interior Point method then compared with Linear Programming Method using Matpower program.
Syafii Syafii, Ikhwannul Kadri Masrul
doaj +1 more source
High performance interior point methods for three-dimensional finite element limit analysis [PDF]
The ability to obtain rigorous upper and lower bounds on collapse loads of various structures makes finite element limit analysis an attractive design tool.
Lyamin, Andrei V. +2 more
core
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
In this paper, a new full-Newton step feasible interior-point method for convex quadratic programming is presented and analyzed. The idea behind this method is to replace the complementarity condition with a non-negative weight vector and use the ...
Yongsheng Rao +2 more
doaj +1 more source
On the relationship between bilevel decomposition algorithms and direct interior-point methods [PDF]
Engineers have been using bilevel decomposition algorithms to solve certain nonconvex large-scale optimization problems arising in engineering design projects.
Miguel, Angel Víctor de +1 more
core +2 more sources
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
On the simplex, interior-point and objective space approaches to multiobjective linear programming
Most Multiple Objective Linear Programming (MOLP) algorithms working in the decision variable space, are based on the simplex algorithm or interior-point method of Linear Programming.
Paschal B Nyiam, Abdellah Salhi
doaj +1 more source
Solving the continuous nonlinear resource allocation problem with an interior point method
Resource allocation problems are usually solved with specialized methods exploiting their general sparsity and problem-specific algebraic structure. We show that the sparsity structure alone yields a closed-form Newton search direction for the generic ...
Rohal, James J., Wright, Stephen E.
core +1 more source

