Polyene Macrolide Antifungal Drugs Trigger Interleukin-1β Secretion by Activating the NLRP3 Inflammasome [PDF]
PLoS ONE, 2011 The use of antimycotic drugs in fungal infections is based on the concept that they suppress fungal growth by a direct killing effect. However, amphotericin and nystatin have been reported to also trigger interleukin-1β (IL-1β) secretion in monocytes but the molecular mechanism is unknown.
Darisipudi, Murthy Narayana +3 more
openaire +9 more sources
Evaluation of Interleukin 1β in Febrile Convulsion [PDF]
Iranian Journal of Allergy, Asthma and Immunology, 2012 Febrile convulsion (FC) is the most common type of seizure in childhood that occurs in 2-5 % of the children younger than 6 years. Interleukin 1β (IL-1β) is a cytokine that contributes to febrile inflammatory responses.
Fatemeh Behmanesh +4 more
doaj +1 more source
Zdorovʹe Rebenka, 2012 There were determined the genotype distribution frequency of interleukin-1β gene gene in promotor region -511C/T. It was defined that interleukin-1β-511*C allele and interleukin-1β-511С/C genotype increase the risk of duodenal ulcer in children ...
S.V. Sokolnyk
doaj +2 more sources
Interleukin-1β gene is not associated with preeclampsia in Taiwanese [PDF]
Taiwanese Journal of Obstetrics & Gynecology, 2012 Objective: To identify associations between the interleukin-1β gene and preeclampsia in Taiwanese women. Methods and Materials: We genotyped Taiwanese population (102 women with preeclampsia and 148 controls) for two polymorphisms of the interleukin-1β ...
Lin Kang +4 more
doaj +2 more sources
Lesió i protecció de les cèl·lules beta en el trasplantament d'illots pancreàtics [PDF]
, 2007 [cat] El trasplantament d'illots pancreàtics pot ser una bona teràpia per els malalts amb diabetis mellitus de tipus 1, però hi ha alguns problemes que cal solventar abans que sigui un tractament estès.
Montolio Rusiñol, Marta
core +6 more sources
Truncated Chicken Interleukin-1β with Increased Biologic Activity [PDF]
, 2003 Chicken interleukin-1β (ChIL-1β) is synthesized as a precursor molecule that unlike its mammalian counterpart, lacks a typical caspase-1 cleavage site. Therefore, it was unclear if proteolytic cleavage of ChIL-1β can occur and if cleavage might modulate ...
Erno Duda +10 more
core +1 more source
Peptidoglycan and teichoic acid fromStaphylococcus epidermidisstimulate human monocytes to release tumour necrosis factor-α, interleukin-1β and interleukin-6 [PDF]
FEMS Immunology & Medical Microbiology, 1993 Cytokines play a major role in the pathophysiology of septic shock. In this study, human peripheral blood monocytes were stimulated with peptidoglycan and teichoic acid, purified from a strain of Staphylococcus epidermidis. Polymyxin B (PM-B) was added to avoid the effects of possible contamination with endotoxin.
E, Mattsson +5 more
openaire +2 more sources
Natriuretic peptide receptors regulate cytoprotective effects in an ex vivo human 3D/bioreactor model [PDF]
, 2013 IntroductionThe present study examined the effect of C-type natriuretic peptide (CNP) and biomechanical signals on anabolic and catabolic activities in chondrocyte/agarose constructs.MethodsNatriuretic peptide (Npr) 2 and 3 expression were compared in ...
Salter, Donald M +31 more
core +1 more source
Peran IL-1 β pada Sepsis dan Gangguan Ginjal Akut Bayi Lahir Prematur
Sari Pediatri, 2020 Latar belakang. Interleukin-1β berperan dalam kejadian infeksi/inflamasi pada bayi prematur yang dapat menyebabkan gejala klinis berat. Imaturitas organ dapat menyebabkan kejadian inflamasi yang dapat merangsang pembentukan sitokin, salah satunya ...
Fiva Aprilia Kadi +3 more
doaj +1 more source
Isoflurane induces learning impairment that is mediated by interleukin 1β in rodents. [PDF]
PLoS ONE, 2012 Postoperative cognitive decline is a clinical syndrome. Volatile anesthetics are commonly used during surgery. It is conceivable that volatile anesthetics may contribute to postoperative cognitive decline.
Lin Cao +3 more
doaj +1 more source