Results 21 to 30 of about 244,530 (240)

Metformin Inhibits the Production of Reactive Oxygen Species from NADH:Ubiquinone Oxidoreductase to Limit Induction of Interleukin-1β (IL-1β) and Boosts Interleukin-10 (IL-10) in Lipopolysaccharide (LPS)-activated Macrophages [PDF]

Journal of Biological Chemistry, 2015
Metformin, a frontline treatment for type II diabetes mellitus, decreases production of the pro-form of the inflammatory cytokine IL-1β in response to LPS in macrophages. We found that it specifically inhibited pro-IL-1β production, having no effect on TNF-α.
Beth Kelly, Gillian M. Tannahill, Michael P. Murphy, Luke A. J. O'Neill   +3 more
openaire   +4 more sources

Impact of Proinflammatory Cytokines: (Interleukin 6, Interleukin 1α, and Interleukin 1β) on Biochemical Parameters in Severe Acute Respiratory Syndrome Coronavirus 2 Patients in Iraq

Biomedical and Biotechnology Research Journal, 2022
Background: The cytokine storm and specific biochemical results were both observed during Coronavirus disease 2019 (COVID-19) infection. The aim of this study was to see if there was any correlation between biochemical findings and cytokine levels ...
Ismael Raheem Al-Muhana, Mohanad Mohsin Ahmed, Ishaq Raheem Al-Muhana, Baraa Akeel AL-Hasan   +3 more
doaj   +1 more source

Curcuminoids extract, hydrolyzed collagen and green tea extract synergically inhibit inflammatory and catabolic mediator's synthesis by normal bovine and osteoarthritic human chondrocytes in monolayer. [PDF]

PLoS ONE, 2015
The main objective of this study was to assess the in vitro effects of curcuminoids extract, hydrolyzed collagen and green tea extract in normal bovine chondrocytes and osteoarthritic human chondrocytes cultured in monolayer. This study also investigated
Fanny Comblain, Christelle Sanchez, Isabelle Lesponne, Marc Balligand, Samuel Serisier, Yves Henrotin   +5 more
doaj   +1 more source

Interleukin‐1β Disruption Protects Male Mice From Heart Failure With Preserved Ejection Fraction Pathogenesis

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background Heart failure with preserved ejection fraction (HFpEF) is a significant unmet need in cardiovascular medicine and remains an untreatable cardiovascular disease.
Balaji K. Srinivas, Aya Bourdi, Jacob D. O'Regan, Kumar D. Malavalli, Nour‐Eddine Rhaleb, Souad Belmadani, Khalid Matrougui   +6 more
doaj   +1 more source

NKT Cells Join the Two Step for Inflammasome-Independent IL-1β Release

Cell Reports, 2020
The cytokine interleukin-1β (IL-1β) is critical for antimicrobial defenses; the inflammasome pathway typically controls IL-1β release, but pathogens often evade this pathway. In this issue, Donado et al. (2020) describe an alternative, two-cell model, to
Jelena S. Bezbradica, Sebastian Joyce
doaj   +1 more source

Regulation of electrolyte transport with IL-1β in rabbit distal colon

Mediators of Inflammation, 1995
Interletrkin-1β levels are elevated in inflammatory bowel disease. In this study the mechanism by which interleukin-1β affects electrolyte transport in the rabbit distal colon, was investigated.
F. R. Homaidan, H. Desai, L. Zhao, G. Broutman, R. Burakoff   +4 more
doaj   +1 more source

Assessment of salivary interleukin-1β (IL-1β), prostaglandin E2(PGE2) levels and pain intensity in children and adults during initial orthodontic treatment

Journal of Orthodontic Science, 2019
OBJECTIVES: To investigate pain intensity, interleukin-1β and prostaglandin E2 values in saliva during initial orthodontic treatment among varying age groups and their correlation between these mediators.
Amrit S Maan, Anand K Patil
doaj   +1 more source

Additional file 1: of Interleukin-1β induces CXCR3-mediated chemotaxis to promote umbilical cord mesenchymal stem cell transendothelial migration

, 2018
Table S1. Sequences of primers used for quantitative real-time polymerase chain reaction experiments. (DOCX 12 kb)
Guo, Yu-Chien, Chiu, Yun-Hsuan, Chen, Chie-Pein, Wang, Hwai-Shi   +3 more
openaire   +1 more source

Pro-Inflammatory Levels of Interleukin-1α-Like Bioactivity Are Present in the Majority of Open Comedones in Acne Vulgaris

Journal of Investigative Dermatology, 1992
The factors that initiate the inflammatory response in acne are not known. The presence of pro-inflammatory cytokines in acne comedones was therefore investigated. One hundred eight open comedones were collected from 18 untreated acne patients (10 male, 8 female).
Ingham, Eileen, Eady, E Anne, Goodwin, Christina E, Cove, Jonathan H, Cunliffe, William J   +4 more
openaire   +2 more sources

Effects of interleukine-1β (IL-1β) and tumor necrosis factor-α (TNF-α ) on dopamine of the cerebral palsy

Asian Journal of Tropical Biotechnology, 2004
The caused of disability on cerebral palsy is unknown, but the human cerebral hypoxic, which affected to the motor cortex and motor pathways in the brain is believed cause of it. The major clinical manifestations are abnormality of movements and posture patterns. The immunity against the cerebral palsy (CP) is unknown, but interleukine-1β (IL-1β) and
openaire   +1 more source