Results 21 to 30 of about 542,868 (256)

Relationship between IL-1β production and endodontic status of human periapical lesions [PDF]

Vojnosanitetski Pregled, 2017
Background/Aim. Apical periodontitis is mainly caused by bacterial infection within the root canal and periapical bone destruction which are prominent features of this lesion.
Popovska Lidija, Dimova Cena, Evrosimoska Biljana, Stojanovska Vera, Muratovska Ilijana, Cetenović Bojana, Marković Dejan   +6 more
doaj   +1 more source

Interleukin-1β Promotes Repair of the CNS [PDF]

, 2001
Interleukin-1β (IL-1β) is a proinflammatory cytokine associated with the pathophysiology of demyelinating disorders such as multiple sclerosis and viral infections of the CNS.
Chaplin, David D., Matsushima, Glenn K., Jeffrey L. Mason, Suzuki, Kinuko, Kinuko Suzuki, Glenn K. Matsushima, Mason, Jeffrey L., David D. Chaplin   +7 more
core   +1 more source

Interleukin-1β sequesters hypoxia inducible factor 2α to the primary cilium. [PDF]

, 2013
BACKGROUND: The primary cilium coordinates signalling in development, health and disease. Previously we have shown that the cilium is essential for the anabolic response to loading and the inflammatory response to interleukin-1β (IL-1β).
Wann, AK, Wann, Angus K.T., Chapple, JP, Knight, MM, Knight, Martin M., Thompson, CL, Thompson, Clare L., Chapple, J. Paul   +7 more
core   +1 more source

Impact of Proinflammatory Cytokines: (Interleukin 6, Interleukin 1α, and Interleukin 1β) on Biochemical Parameters in Severe Acute Respiratory Syndrome Coronavirus 2 Patients in Iraq

Biomedical and Biotechnology Research Journal, 2022
Background: The cytokine storm and specific biochemical results were both observed during Coronavirus disease 2019 (COVID-19) infection. The aim of this study was to see if there was any correlation between biochemical findings and cytokine levels ...
Ismael Raheem Al-Muhana, Mohanad Mohsin Ahmed, Ishaq Raheem Al-Muhana, Baraa Akeel AL-Hasan   +3 more
doaj   +1 more source

Natriuretic peptide receptors regulate cytoprotective effects in an ex vivo human 3D/bioreactor model [PDF]

, 2013
IntroductionThe present study examined the effect of C-type natriuretic peptide (CNP) and biomechanical signals on anabolic and catabolic activities in chondrocyte/agarose constructs.MethodsNatriuretic peptide (Npr) 2 and 3 expression were compared in ...
Salter, Donald M, Salter, Donald M., Ramachandran, Manoj, Adrian J Hobbs, Hobbs, Adrian J., Ramachandran, M, Moyes, AJ, Amie J Moyes, Peake, Nicholas, Bader, Dan L, Bader, DL, Chowdhury, Tina T., Donald M Salter, Pramod Achan, Bader, Dan L., Peake, N, Su, N, Achan, P, Hobbs, AJ, Salter, DM, Nyan Su, Achan, Pramod, Nicholas Peake, Chowdhury, TT, Moyes, Amie J., Dan L Bader, Tina T Chowdhury, Su, Nyan, Chowdhury, Tina T, Hobbs, Adrian J, Moyes, Amie J, Manoj Ramachandran   +31 more
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Curcuminoids extract, hydrolyzed collagen and green tea extract synergically inhibit inflammatory and catabolic mediator's synthesis by normal bovine and osteoarthritic human chondrocytes in monolayer. [PDF]

PLoS ONE, 2015
The main objective of this study was to assess the in vitro effects of curcuminoids extract, hydrolyzed collagen and green tea extract in normal bovine chondrocytes and osteoarthritic human chondrocytes cultured in monolayer. This study also investigated
Fanny Comblain, Christelle Sanchez, Isabelle Lesponne, Marc Balligand, Samuel Serisier, Yves Henrotin   +5 more
doaj   +1 more source

Intracerebral NMDA Injection Stimulates Production of Interleukin-1Β in Perinatal Rat Brain [PDF]

, 1996
Susceptibility to NMDA neurotoxicity peaks in the early postnatal period in rats. Although indirect evidence suggests that interleukin-1Β is a mediator of NMDA neurotoxicity in perinatal rats, direct confirmation of NMDA-induced interleukin-1Β production
Poole, S., Bristow, A. F., Tilders, F., S. Poole, A. F. Bristow, P. Hagan, Hagan, P., F. S. Silverstein, F. Tilders   +8 more
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Mechanisms of Lung Injury in a Mouse Model of Bronchopulmonary Dysplasia [PDF]

, 2009
Bronchopulmonary dysplasia (BPD) is a chronic lung disease that affects preterm infants. Increased levels of inflammatory mediators in the amniotic fluid and in the lungs of preterm infants are associated with the development of BPD.
Hogmalm, Anna
core   +1 more source

Interleukin‐1β Disruption Protects Male Mice From Heart Failure With Preserved Ejection Fraction Pathogenesis

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background Heart failure with preserved ejection fraction (HFpEF) is a significant unmet need in cardiovascular medicine and remains an untreatable cardiovascular disease.
Balaji K. Srinivas, Aya Bourdi, Jacob D. O'Regan, Kumar D. Malavalli, Nour‐Eddine Rhaleb, Souad Belmadani, Khalid Matrougui   +6 more
doaj   +1 more source

Targeting Interleukin-1β Reduces Leukocyte Production After Acute Myocardial Infarction [PDF]

, 2015
Background—Myocardial infarction (MI) is an ischemic wound that recruits millions of leukocytes. MI-associated blood leukocytosis correlates inversely with patient survival, yet the signals driving heightened leukocyte production after MI remain ...
Sun, Yuan, Heidt, Timo, Tricot, Benoit, Weissleder, Ralph, Swirski, Filip, Swirski, Filip K., Hulsmans, Maarten, Dutta, Partha, Libby, Peter, Courties, Gabriel, Iwamoto, Yoshiko, Nahrendorf, Matthias, Sager, Hendrik B., Sebas, Matthew, Wojtkiewicz, Gregory R.   +14 more
core   +1 more source