Results 31 to 40 of about 542,868 (256)

NKT Cells Join the Two Step for Inflammasome-Independent IL-1β Release

Cell Reports, 2020
The cytokine interleukin-1β (IL-1β) is critical for antimicrobial defenses; the inflammasome pathway typically controls IL-1β release, but pathogens often evade this pathway. In this issue, Donado et al. (2020) describe an alternative, two-cell model, to
Jelena S. Bezbradica, Sebastian Joyce
doaj   +1 more source

Regulation of electrolyte transport with IL-1β in rabbit distal colon

Mediators of Inflammation, 1995
Interletrkin-1β levels are elevated in inflammatory bowel disease. In this study the mechanism by which interleukin-1β affects electrolyte transport in the rabbit distal colon, was investigated.
F. R. Homaidan, H. Desai, L. Zhao, G. Broutman, R. Burakoff   +4 more
doaj   +1 more source

Assessment of salivary interleukin-1β (IL-1β), prostaglandin E2(PGE2) levels and pain intensity in children and adults during initial orthodontic treatment

Journal of Orthodontic Science, 2019
OBJECTIVES: To investigate pain intensity, interleukin-1β and prostaglandin E2 values in saliva during initial orthodontic treatment among varying age groups and their correlation between these mediators.
Amrit S Maan, Anand K Patil
doaj   +1 more source

Acute Phase Protein Response and Polymorphonuclear Leukocyte Cathepsin G Release After Slow Interleukin-1 Stimulation in the Rat

Mediators of Inflammation, 1994
In this work we have studied the acute phase protein response and degranulation of polymorphonuclear leukocytes in vivo in the rat after a slow interleukin-1β stimulation.
Peter Björk, Thorarinn Gudmundsson, Kjell Ohlsson   +2 more
doaj   +1 more source

Increased interleukin 1α and interleukin 1β expression is involved in the progression of periapical lesions in primary teeth

BMC Oral Health, 2018
Background Interleukin 1 (IL-1) is involved in bone resorption. However, the role of IL-1 in periapical lesions characterized by periapical bone destruction in primary teeth has not yet been fully elucidated.
Ning-Yan Yang, Yan Zhou, Huan-Ying Zhao, Xiao-Yong Liu, Zheng Sun, Jia-Jian Shang   +5 more
doaj   +1 more source

Interleukin-1β promotes interleulin-6 expression via ERK1/2 signaling pathway in canine dermal fibroblasts

, 2019
Interleukin-6 (IL-6) is a pleiotropic cytokine involved in the regulation of the immune response and inflammation. In this study, we investigated effect of the proinflammatory cytokine interleukin-1β (IL-1β) on IL-6 expression in canine dermal ...
Taku Kitanaka (3350276), Tomohiro Nakayama (30894), Nanako Kitanaka (3350285), Tadayoshi Konno (3350282), Kanae Sugiura (7042421), Hiroshi Sugiya (412101), Rei Nakano (820735), Shinichi Namba (3350288)   +7 more
core   +1 more source

Candida albicans Morphogenesis Is Not Required for Macrophage Interleukin 1β Production

mBio, 2013
The interaction of Candida albicans with macrophages induces the production of interleukin 1β (IL-1β) through inflammasome activation in a process that is required for host survival. C.
Melanie Wellington, Kristy Koselny, Damian J. Krysan   +2 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Interleukin-1α, Interleukin-1β, and Interleukin-1Ra Polymorphisms in Febrile Seizures

, 2005
Febrile seizures are the most common form of childhood seizures. The exact mechanism promoting convulsions during a common febrile illness remains unknown, but it is accepted that genetic influences are likely to account for at least some of the cases ...
Olcay Yein, Tosun, Özgür, Yeǧin, Olcay, Özgür Duman, Mesut Coşkun, COŞKUN, MESUT, Özgür Tosun, Baysal, YUNUS EMRE, DUMAN, ÖZGÜR, Şenay Haspolat, Yunus Baysal, HASPOLAT, ŞENAY   +11 more
core   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

FEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda, Sreerama Chaitanya Sridhara, Aura Carreira   +2 more
wiley   +1 more source