Results 311 to 320 of about 24,572,041 (402)

Interleukin-1 receptor-dependent and -independent caspase-1 activity in retinal cells mediated by receptor interacting protein 2. [PDF]

Front Cell Dev Biol
Coughlin BA, Christian B, Trombley B, Mohr S.   +3 more
europepmc   +1 more source

An Intelligent and Conductive Hydrogel with Multiresponsive and ROS Scavenging Properties for Infection Prevention and Anti‐Inflammatory Treatment Assisted by Electrical Stimulation for Diabetic Wound

Advanced Science, EarlyView.
This study introduces a novel therapeutic approach that employs a conductive hydrogel (HEPP) responsive to near‐infrared light, pH levels, and reactive oxygen species. Its goal is to enhance the healing environment affected by elevated glucose levels, insufficient oxygen, and bacterial infections in diabetes‐related wounds.
Tao Zhang, Zongwu Meng, Haoyu Yu, Ping Ding, Tianhan Kai   +4 more
wiley   +1 more source

Human proximal tubular epithelial cell interleukin-1 receptor signalling triggers G2/M arrest and cellular senescence during hypoxic kidney injury. [PDF]

Cell Death Dis
Giuliani KTK, Nag P, Adams BC, Wang X, Hong S, Grivei A, Johnston RL, Waddell N, Ho KKC, Tian Y, Khan MA, Kim CS, Ng MSY, Gobe G, Ungerer JPJ, Forbes JM, Healy HG, Kassianos AJ.   +17 more
europepmc   +1 more source

Injectable and Sprayable Thermoresponsive Hydrogel with Fouling‐Resistance as an Effective Barrier to Prevent Postoperative Cardiac Adhesions

Advanced Science, EarlyView.
Postoperative cardiac adhesions lead to numerous difficulties in reoperation procedures. Here, a thermo‐responsive in situ formed hydrogel is shown to can reliably cover the wounds after a convenient spraying or injection and significantly reduce adhesion formation in primary and recurrent cardiac injury adhesion models.
Kun Shi, Tao Li, Xulin Hu, Wen Chen, Yan Yu, Zhongwu Bei, Liping Yuan, Qi Tong, Jiafeng Liu, Qiang Fan, Yongjun Qian, Zhiyong Qian   +11 more
wiley   +1 more source

Interleukin-1 Blockers: A Paradigm Shift in the Treatment of Recurrent Pericarditis. [PDF]

Life (Basel)
Lazarou E, Koutsianas C, Theofilis P, Lazaros G, Vassilopoulos D, Vlachopoulos C, Tsioufis C, Imazio M, Brucato A, Tousoulis D.   +9 more
europepmc   +1 more source

Smart Organic–Inorganic Copolymer Nanoparticles Distinguish Between Microglia and Cancer Cells for Synergistic Immunotherapy in Glioma

Advanced Science, EarlyView.
The tumor microenvironment‐responsive nanoagonists are developed using an organic–inorganic copolymer composed of the polymer (PC6AB) and manganous phosphate ionic oligomers (MnP). PC6AB with membranolytic activity selectively interacts with tumor cell membranes to induce immunogenic cell death, while MnP activates the STING pathway in immune cells ...
Shiming Zhang, Kun Shang, Lidong Gong, Qian Xie, Jianfei Sun, Meng Xu, Xunbin Wei, Zhaoheng Xie, Xinyu Liu, Hao Tang, Zhengren Xu, Wei Wang, Haihua Xiao, Zhiqiang Lin, Hongbin Han   +14 more
wiley   +1 more source

Effect of genetic polymorphisms of interleukin-1 beta on the microscopic portal vein invasion and prognosis of hepatocellular carcinoma. [PDF]

J Hepatobiliary Pancreat Sci
Namba Y, Kobayashi T, Tadokoro T, Fukuhara S, Oshita K, Matsubara K, Honmyo N, Kuroda S, Ohira M, Ohdan H.   +9 more
europepmc   +1 more source

Single‐Cell Analysis Reveals that Vitamin C Inhibits Bone Metastasis of Renal Cancer via Cell Cycle Arrest and Microenvironment Remodeling

Advanced Science, EarlyView.
3D‐cultured renal cancer cells exhibit stem‐like phenotypes and are more efficient in generating bone metastases. Vitamin C treatment can suppress the development of bone metastasis. Single‐cell transcriptomic analysis reveals that vitamin C inhibits metastasis by inducing tumor cell cycle arrest, suppressing osteoclast differentiation, and reducing ...
Jianye Zhang, Qi Zhang, Gang Lin, Ying Wang, Juan Li, Ping Wang, Jie Qi, Yuan Liang, Shiming He, Yanqing Gong, Ninghan Feng, Yang Wang, Yuanyuan Ma, Mei Zhang, Yue Shi, Xuesong Li, Weimin Ci, Liqun Zhou   +17 more
wiley   +1 more source

Deficiency of interleukin-1 receptor antagonist in mice differentially affects bone properties under different genomic backgrounds. [PDF]

Sci Rep
Dong W, Tian C, Li ZG, Bounds M, Ma J, Brand DD, Liu X, Cao Y, Beard A, Yan J, Hasty K, Stuart J, Li K, Cho H, Fitzpatrick EA, Myers LK, Jiao Y, Gu W.   +17 more
europepmc   +1 more source