Results 111 to 120 of about 8,062,997 (306)

Association of an inflammaging score based on IL-6, IL-10 and CXCL9, and frailty with long-term mortality in hospitalized older adults

Immunity & Ageing
Background Aging is accompanied by chronic low-grade inflammation ("inflammaging"), which contributes to increased morbidity and mortality in older adults. This study evaluated the prognostic value of circulating inflammatory biomarkers, i.e. interleukin-
Matilde Sbriscia, Sonia Fantone, Mirko Di Rosa, Francesca Marchegiani, Rina Recchioni, Giulia Matacchione, Chiara Giordani, Francesco Piacenza, Robertina Giacconi, Davide Gentilini, Luciano Calzari, Carlo Fortunato, Gretta Veronica Badillo Pazmay, Monia Cecati, Sara Caccese, Emanuele Francini, Rosanna Maniscalco, Maurizio Cardelli, Elena Tortato, Federica Lenci, Yuri Rosati, Maurizio Burattini, Roberto Antonicelli, Andrea Corsonello, Luca Soraci, Leonardo Biscetti, Massimiliano Fedecostante, Riccardo Sarzani, Marco Malavolta, Tiziana Casoli, Maria Conte, Silvia Di Valerio, Angelica Giuliani, Antonio Domenico Procopio, Fabrizia Lattanzio, Anna Rita Bonfigli, Antonio Cherubini, Claudio Franceschi, Jacopo Sabbatinelli, Fabiola Olivieri   +39 more
doaj   +1 more source

Pull‐and‐Push Nanotherapeutic Hydrogels: Scavenging Inflammatory Triggers While Driving Tissue Regeneration in Burn Wounds

Advanced Functional Materials, EarlyView.
A nanounit‐assembled hydrogel employing a “pull‐and‐push” strategy simultaneously scavenges pro‐inflammatory cell‐free DNA (cfDNA) and delivers regenerative therapeutics in response to burn‐induced hyperthermia. By repolarizing macrophages and promoting angiogenesis, this multifunctional platform accelerates burn wound healing, offering a blueprint for
Han‐Sem Kim, Seong‐Jin Shin, Sak Lee, Nandin Mandakhbayar, Ji‐Hye Kang, Da‐Young Kong, Seong‐Doo Hong, Ueon Sang Shin, Hae‐Won Kim, Jung‐Hwan Lee   +9 more
wiley   +1 more source

Interleukin gének relatív expressziós szintjének változása ellés előtti D-vitamin kezelés hatására holstein-fríz tehenek méhlepényében

, 2018
A dolgozatomban a D-vitamin többlet bevitel hatását vizsgáltam három gén (IL 1ß, IL6, IL10) vizsgálatával. A vizsgálatunk célja a D-vitaminos kezelés hatására megállapítani az expressziós szintet, a tejelő holstein-fríz tehenek placentájából vett mintái ...
Biszku, Barbara Ildikó
core  

Human mid-gestation amniotic fluid contains interleukin-16 bioactivity

, 2009
CD4-positive cells are detectable in the human fetal gastrointestinal tract from 11 weeks of gestation. Interleukin-16 (IL-16) is a chemoattractant for CD4(+) cells and, via fetal swallowing of amniotic fluid, could mediate the influx of CD4(+) cells ...
Warner, J., John W. Holloway, Thornton, Catherine A., Diaper, Norma D., Holloway, John W., Diaper, N., Shute, Janis K., Warner, John O., Catherine A. Thornton, Janis K. Shute, John O. Warner, Holloway, J., Cathy Thornton, Holloway, Judith A., Shute, Jan, Norma D. Diaper, Thornton, C., Judith A. Holloway   +17 more
core   +1 more source

Targeting Post‐Irradiation Thyroid Dysfunction: Electrospun Scaffolds As A Dual‐Action Approach for Antioxidant and Immune Modulation

Advanced Healthcare Materials, EarlyView.
Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim, Ella‐Louise Handley, Daniel Grant, Lizi M. Hegarty, Elaine Emmerson, Anthony Callanan   +5 more
wiley   +1 more source

Infusible Extracellular Matrix Biomaterial Enhances Cell‐Specific Pro‐Repair Responses Following Acute Myocardial Infarction

Advanced Healthcare Materials, EarlyView.
We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...
Joshua M. Mesfin, Alexander Chen, Quincy P. Lyons, Michael B. Nguyen, Maria L. Karkanitsa, Justin Yu, Van K. Ninh, Emily Gardner, Elyse G. Wong, Sriya N. Paleti, Julian Cheng, Benjamin D. Bridgelal, Kate E. Reimold, Selena Cao, Connor Uhre, Colin G. Luo, Zhenxing Fu, Kevin R. King, Karen L. Christman   +18 more
wiley   +1 more source

Differential effects of age on chicken heterophil functional activation by recombinant chicken interleukin-2

, 2002
Interleukin-2 (IL-2) exercises an array of biological effects on many cells including the functional activation of cells of the innate immune response.
Pete Kaiser, Kogut, Michael, Michael Kogut, Kaiser, Pete, Lisa Rothwell, Rothwell, Lisa   +5 more
core   +1 more source

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

Advanced Healthcare Materials, EarlyView.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami, Yeonwoo Park, Seong Kyeong Jo, Min Hee Kim, Jae Hwang Song   +4 more
wiley   +1 more source

Association of Interleukin-10 Polymorphisms with Schizophrenia: A Meta-Analysis

, 2014
Background: The involvement of cytokines in schizophrenia (SZ) has been proposed in recent years and various studies have accumulated convergent lines of evidence.
Gao, Lei, Li, Zhao, Chang, Suhua, Wang, Jing   +3 more
core  

Heterogeneity in the granulomatous response to mycobacterial infection in patients with defined genetic mutations in the interleukin 12-dependent interferon-gamma production pathway

, 2002
Granulomatous Diseases Review Heterogeneity in the granulomatous response to mycobacterial infection in patients with defined genetic mutations in the interleukin 12-dependent interferon-gamma production ...
Kumararatne, D.S., Baretto, Richard, De Heer, E., J.F. EMILE, Ottenhoff, THM, De Heer, E, Edgar, JD, Binch, J., Ottenhoff, T.H., Casanova, J.L., Lammas, David, Lammas, D.A., Edgar, J, Kumararatne, DS, Panchalingam, S, Novelli, V., E. DE HEER, Drysdale, P, Binch, J, Ottenhoff, TH, Panchalingam, S., Emile, JF, Drysdale, Pamela, C. MACLENNAN, T. H. M. OTTENHOFF, Ben-smith, Anne, Novelli, V, P. DRYSDALE, MacLennan, Calman, R. BARETTO, Casanova, JL, J. BINCH, Ben-Smith, A., Casanova, J-L, Ben-Smith, A, Drysdale, P., Emile, J.F., D. S. KUMARARATNE, Baretto, R, Baretto, R., S. PANCHALINGAM, J.-L. CASANOVA, MacLennan, C, J. D. EDGAR, A. BEN-SMITH, Kumararatne, Dinakantha, D. A. LAMMAS, MacLennan, C., Lammas, David A, V. NOVELLI   +49 more
core   +1 more source