Results 21 to 30 of about 76,840 (266)

Differential Effect of SARS-CoV-2 Spike Glycoprotein 1 on Human Bronchial and Alveolar Lung Mucosa Models: Implications for Pathogenicity

Viruses, 2021
Background: The SARS-CoV-2 spike protein mediates attachment of the virus to the host cell receptor and fusion between the virus and the cell membrane.
Mizanur Rahman, Martin Irmler, Sandeep Keshavan, Micol Introna, Johannes Beckers, Lena Palmberg, Gunnar Johanson, Koustav Ganguly, Swapna Upadhyay   +8 more
doaj   +1 more source

Cytoplasmic tail of IL-13Ralpha2 regulates IL-4 signal transduction [PDF]

, 2009
IL (interleukin)-4 and IL-13 are key cytokines in the pathogenesis of allergic inflammatory disease. IL-4 and IL-13 share many functional properties as a result of their utilization of a common receptor complex comprising IL-13Ralpha1 (IL-13 receptor ...
Donna E. Davies, Holgate, Stephen T, Isabelle Kirby, Ida Karin Nordgren, Tavassoli, Ali, Davies, Donna E, Holloway, John W, Andrews, Allison-Lynn, Stephen T. Holgate, Nordgren, Ida Karin, John W. Holloway, Kirby, Isabelle, Allison-Lynn Andrews, Ali Tavassoli   +13 more
core   +1 more source

Saccharomyces boulardii attenuates inflammatory response induced by Clostridium perfringens via TLR4/TLR15-MyD8 pathway in HD11 avian macrophages

Poultry Science, 2020
Macrophages are professional phagocytic cells that play a critical role in initiating immune responses by presenting antigen and phagocytic clearance. The macrophages can be targeted for immunomodulation by beneficial microbes, such as probiotics.
Baikui Wang, Altaf Hussain, Yuanhao Zhou, Zihan Zeng, Qi Wang, Peng Zou, Li Gong, Pengwei Zhao, Weifen Li   +8 more
doaj   +1 more source

Expression of interleukin-18 receptor in fibroblast-like synoviocytes [PDF]

, 2001
An excess of the proinflammatory substance IL-18 is present in joints of patients with rheumatoid arthritis (RA), and expression of IL-18 receptor (IL-18R) regulates IL-18 bioactivity in various cell types.
Hoelzer, Dieter (Prof. Dr.), Rehart, Stefan, Kalina, Uwe, Kessler, Uta, Kukoc-Zivojnov, Natasa, Kaltwasser, Joachim Peter (Prof. Dr.), Ottmann, Oliver G., Möller, Burkhard   +7 more
core   +1 more source

Expression and Prognostic Value of PIK3CA, VEGF, IL-8, IL-10, and RIP2 in Diffuse Large B-Cell Lymphoma

International Journal of Clinical Practice, 2022
Background. To explore clinical features and prognostic value of vascular endothelial growth factor (VEGF), interleukin (IL) 8, IL-10, phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha (PIK3CA), and receptor-interacting protein-2 ...
Na Shen, Yanfang Yu, Ruiying Zhang, Ying Guo, Mei Liu, Mengtian Tan, Jianxia Liu, Jing Bai, Li Li, Keyu Liu, Ran Wang, Jinglan He   +11 more
doaj   +1 more source

Effects of dietary fermented product supplementation on metabolism pathways of antioxidant, inflammatory, and lipid metabolism pathways-a potential crosstalk [PDF]

Asian-Australasian Journal of Animal Sciences, 2020
Objective This study was conducted to fathom the underlying mechanisms of nutrition intervention and redox sensitive transcription factors regulated by Antrodia cinnamomea fermented product (FAC) dietary supplementation in broiler chickens.
M. T. Lee, W. C. Lin, L. J. Lin, S. Y. Wang, S. C. Chang, T. T. Lee   +5 more
doaj   +1 more source

Interleukin-4 receptor alpha gene variants and allergic disease [PDF]

, 2000
The interleukin-4 (IL-4) signalling cascade has been identified as a pathway potentially important in the development of asthma. Genetic variants within this signalling pathway might contribute to the risk of developing asthma in a given individual.
Ian P Hall, Hall, Ian P., Hall Ian P
core   +1 more source

Spa therapy induces clinical improvement and protein changes in patients with chronic back pain

Reumatismo, 2019
This study is primarily aimed at assessing serum changes on a large panel of proteins in patients with chronic back pain following spa therapy, as well as evaluating different spa therapy regimens as a preliminary exploratory clinical study.
M.M. Angioni, A. Denotti, S. Pinna, C. Sanna, F. Montisci, G. Dessole, A. Loi, A. Cauli   +7 more
doaj   +1 more source

Hyperbaric oxygen treatment on keloid tumor immune gene expression

Chinese Medical Journal, 2021
. Background:. Hyperbaric oxygen treatment (HBOT) has been demonstrated to influence the keloid recurrence rate after surgery and to relieve keloid symptoms and other pathological processes in keloids.
Chun-Hu Wang, Meng-Jie Shan, Hao Liu, Yan Hao, Ke-Xin Song, Huan-Wen Wu, Tian Meng, Cheng Feng, Zheng Qi, Zhi Wang, You-Bin Wang, Ning-Ning Wang   +11 more
doaj   +1 more source

Regulation of thrombopoietin receptor expression and function [PDF]

, 2004
Of the many cells in the body, the hematopoietic cells are among those with the highest rate of self-renewal and turnover. The production and destruction of these cells are tightly controlled by a number of hematopoietic growth factors, in particular by ...
Coers, Jörn
core   +1 more source