Results 31 to 40 of about 76,840 (266)
Identification of the immune-related biomarkers in Behcet’s disease by plasma proteomic analysis
Background This study aimed to investigate the expression profile of immune response-related proteins of Behcet’s disease (BD) patients and identify potential biomarkers for this disease. Methods Plasma was collected from BD patients and healthy controls
Huan Liu +7 more
doaj +1 more source
Interleukin-18 (IL-18), a recently described member of the IL-1 cytokine superfamily, is now recognized as an important regulator of innate and acquired immune responses.
McInnes, I.B. +2 more
core +1 more source
Case Report: Serum sickness induced by dupilumab—clinical insights and Olinkproteomic analysis
Dupilumab is a humanized monoclonal antibody that targets interleukin-4 (IL-4) and IL-13 pathways, commonly used in the treatment of various inflammatory conditions.
Hongguo Zhu +4 more
doaj +1 more source
Distinct damage levels and transcriptional responses of lung in Hezuo pigs and Bama pigs during cold exposure [PDF]
Objective The aim of the present study is to compare cold adaptation mechanisms between cold-tolerant Hezuo and cold-sensitive Bama pigs. Methods A total of 40 healthy pigs (75 days old), including 20 Hezuo pigs and 20 Bama pigs, were used in this study.
Yajuan Li +3 more
doaj +1 more source
IL-13R alpha 2 reverses the effects of IL-13 and IL-4 on bronchial reactivity and acetylcholine-induced Ca2+ signaling [PDF]
Background: The interleukins IL-4 and IL-13 play a key role in the pathophysiology of asthma. The interleukin receptor IL-13R alpha 2 is believed to act as a decoy receptor, but until now, the functional significance of IL-13R alpha 2 remains vague ...
Kellner, Julia +6 more
core +1 more source
Comparative study of gp130 cytokine effects on corticotroph AtT-20 cells - Redundancy or specificity of neuroimmunoendocrine modulators? [PDF]
Objective: This comparative in vitro study examined the effects of all known gp130 cytokines on murine corticotroph AtT-20 cell function. Methods: Cytokines were tested at equimolar concentrations from 0.078 to 10 nM.
Kopp, F. B. +9 more
core +1 more source
: Quercetin, the main component of flavonoids, has a wide range of biological actions. Quercetin can be made into a variety of additives for practice, because of the stable chemical structure and water-soluble derivatives.
J.X. Yang +6 more
doaj +1 more source
Resumen: Introducción: El mepolizumab es un anticuerpo monoclonal que bloquea la interleuquina 5 circulante (IL5). El benralizumab se une a la subunidad alfa del receptor de la IL 5 induciendo la eliminación directa de eosinófilos y basófilos.
María José Espinosa de los Monteros Garde +2 more
doaj +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
The role of interleukin-4 receptor alpha on smooth muscle cells during helminth infection [PDF]
Includes abstract.Includes bibliographical references (leaves 101-111).Interleukin-4 receptor alpha (IL-4Ra) signaling, mediated by the ligands IL-4 and IL- 13, is important for effective host protection during murine Nippostrongylus brasiliensis (N ...
Brombacher, Tiroyaone M H
core

