Results 121 to 130 of about 632,731 (201)

Emerging roles for interleukin-11 in the inflammatory response of intracerebral hemorrhage. [PDF]

Front Neurol
Xue L, Zhu J, Wang H, Wang Z, Yu W.
europepmc   +1 more source

Condition‐Associated Pattern Extraction and Recovery From Multi‐Condition Single‐Cell RNA‐seq Data With CAPER

Advanced Science, EarlyView.
Decoupling biological signals from unwanted variation in multi‑condition single‑cell RNA sequencing data remains challenging. CAPER disentangles condition‑associated biological effects from sample heterogeneity through matrix factorization, producing interpretable latent factors and a batch‑corrected expression matrix.
Ye Li, Jin Ning, An Wang, Minxi Shi, Yuanze Chen, Guoliang Liu, Shiquan Sun   +6 more
wiley   +1 more source

Fibroblast-derived interleukin-11 as a potential biomarker for intestinal fibrostenosis in Crohn's disease. [PDF]

Ther Adv Gastroenterol
Tan J, Wu X, Huang W, He J, Nie J, Zhou L, Liu Z, Wang Y, Liu C, Li J, Zhang Y, Chen M, Mao R, Xiong S.   +13 more
europepmc   +1 more source

Identification of an Osteochondral Erosion Process in Gout Driven by Fibrinogen‐Integrin Activation and Local MSU Crystallization

Advanced Science, EarlyView.
Cartilage injury promotes local fibrinogen deposition, which accelerates monosodium urate crystallization and activates integrin‐mediated matrix‐degradation. This self‐amplifying cycle drives gout‐related cartilage erosion. Disrupting fibrinogen deposition or restoring the cartilage barrier could interrupt this vicious cycle.
Hanlin Xu, Simin Bi, Zhechen Liu, Xiaofeng Zhou, Hengwei Qin, Nicola Dalbeth, Minbiao Ji, Yinghui Hua   +7 more
wiley   +1 more source

Non-linear age-related change in human Interleukin-11 and the receptor subunit alpha DNA methylation. [PDF]

Biochem Biophys Rep
Shimura A, Dwaraka VB, Yamanishi K, Seki T, Nishiguchi T, Aoyama B, Ishii T, Phuong NJ, Gorantla N, Nguyen HD, Santiago T, Nishitani S, Smith R, Shinozaki G.   +13 more
europepmc   +1 more source

The Interleukin-11/IL-11 Receptor Promotes Glioblastoma Survival and Invasion under Glucose-Starved Conditions through Enhanced Glutaminolysis. [PDF]

Int J Mol Sci, 2023
Stuart SF, Bezawork-Geleta A, Areeb Z, Gomez J, Tsui V, Zulkifli A, Paradiso L, Jones J, Nguyen HPT, Putoczki TL, Licciardi PV, Kannourakis G, Morokoff AP, Achuthan AA, Luwor RB.   +14 more
europepmc   +1 more source

Targeting p21‐High Senescent Kupffer Cells Nanotherapeutically Potentiates Antitumor Immunity in Advanced Hepatocellular Carcinoma with Portal Vein Tumor Thrombus

Advanced Science, EarlyView.
Schematic illustration of a biomimetic SKEV@AAV platform targeting p21‐high senescent Kupffer cells (sKCs) in hepatocellular carcinoma (HCC) with portal vein tumor thrombus (PVTT). p21‐high sKCs accumulate in the PVTT microenvironment and establish an immunosuppressive, SASP‐rich environment that facilitates tumor cell proliferation and immune evasion.
Na Ta, Shuyi Wang, Boyan Zhang, Ning Liu, Yingchen Han, Aoran Liu, Ying Xu, Tingsong Chen, Ye Zhang, Qiuhua Luo, Tao Han   +10 more
wiley   +1 more source

Psychological Stress Associated Bile Acid Reprogramming Promotes Hepatocellular Carcinoma Progression

Advanced Science, EarlyView.
Depression is increasingly recognized as a risk factor for chronic diseases, yet its biological impact on cancer remains unclear. Using data from more than 490 000 participants across three international cohorts, we show that depression significantly increases the risk of liver cancer.
Ruijiang Zeng, Mengmeng Wang, Kang Wang, Zhuo Xing, Yulong Hong, Tongtong Li, Geng Zong, Chong Yang, Dan Zhang, Zhangling Chen, Xin Jin   +10 more
wiley   +1 more source

CSPG4⁺ extracellular vesicles carry fibronectin and interleukin-11 and reflect radiographic severity in knee osteoarthritis. [PDF]

Osteoarthr Cartil Open
Zhang X, MacFarlane LA, Huebner JL, Tao JJ, Katz JN, Kraus VB.   +5 more
europepmc   +1 more source

Effect of α-Mangostin on Interleukin-11 and Runt-related Transcription Factor-2 Gene Expression on Cell Line Osteoblast Cultures Induced with Lipopolysaccharide. [PDF]

Contemp Clin Dent, 2023
Tantra I, Rizqiawan A, Sumarta NPM, Kamadjaja DB, Soesilowati P, Rahman MZ, Pramono C.   +6 more
europepmc   +1 more source