Results 91 to 100 of about 7,946,940 (284)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Progression independent of relapse activity is a major determinant of long‐term disability in multiple sclerosis, but its immunopathologic basis remains incompletely understood. We investigated whether relapse‐independent progression in radiologically stable relapsing–remitting multiple sclerosis is associated with distinct ...
Antonio Bruno +19 more
wiley +1 more source
Memorias do Instituto Oswaldo Cruz, 2004 Resistance to infection by Leishmania major has been associated with the development of a Th1 type response that is dependent on the presence of interleukin 12 (IL-12).
Sebastião Martins de Souza-Neto +3 more
doaj +1 more source
Truncated Chicken Interleukin-1β with Increased Biologic Activity [PDF]
, 2003 Chicken interleukin-1β (ChIL-1β) is synthesized as a precursor molecule that unlike its mammalian counterpart, lacks a typical caspase-1 cleavage site. Therefore, it was unclear if proteolytic cleavage of ChIL-1β can occur and if cleavage might modulate ...
Erno Duda +10 more
core +1 more source
Endothelial Cell Proteins as Biomarkers in Susac Syndrome
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Susac syndrome (SS) is a rare CD8+ T cell–mediated microangiopathy affecting the brain, retina, and auditory labyrinth. Endothelial injury is thought to be a central mechanism; however, no circulating disease biomarkers are known. We performed targeted proteomic profiling to identify circulating endothelial‐associated proteins as ...
Rohit Benjamin +11 more
wiley +1 more source
Biomédica: revista del Instituto Nacional de Salud, 2007 Introducción. La proteína de membrana 11 de kinetoplástidos, KMP-11, de Trypanosoma cruzi induce inmunidad humoral y celular en ratones capaz de conferir protección frente al reto con el parásito. Objetivo.
Sandra Paola Santander +6 more
doaj +1 more source
Changes in Immune‐Inflammation Status and Prognosis in Pregnancy‐Related Cerebral Venous Thrombosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Distinguishing pathological changes from physiological adaptations in pregnancy‐related cerebral venous thrombosis (CVT) is clinically challenging. This study aimed to characterize coagulation, immune‐inflammation, and dehydration status in these patients and assess their prognostic value.
Xiaoming Zhang +7 more
wiley +1 more source
Effect of Cyperus Rotundus on Cytokine Gene Expression in Experimental Inflammatory Bowel Disease
Iranian Journal of Medical Sciences, 2016 Background: The protective effect of the chloroform extract of Cyperus rotundus (CHCR) is attributed to its anti-inflammatory and antioxidant activities.
Sarika Johari +2 more
doaj
Autoimmune Comorbidities as Modifiers of Phenotypic Heterogeneity in Facioscapulohumeral Dystrophy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Facioscapulohumeral dystrophy type 1 (FSHD1) shows clinical heterogeneity that is only partly explained by D4Z4 repeat unit (RU) size. Although immune and inflammatory mechanisms may contribute to disease variability, the prevalence and clinical impact of autoimmune diseases in FSHD remain unclear.
Jonathan Pini +9 more
wiley +1 more source
Nanoparticle-Mediated Interleukin-12 Cancer Gene Therapy
Journal of Pharmacy & Pharmaceutical Sciences, 2010 Interleukin-12 (Il-12) is a heterodimeric cytokine which has been proved to possess antitumor effects in various animal models via stimulating the immune system.
Crispin Dass +2 more
doaj +1 more source
Interleukin-6 levels in selected 12 plasma sample before and after apo-B depletion.
Interleukin-6 levels in selected 12 plasma sample before and after apo-B depletion.
Chin-Sung Kuo (8878307) +6 more
core +1 more source