Results 251 to 260 of about 576,830 (304)
Cellular Identity Crisis: RD3 Loss Fuels Plasticity and Immune Silence in Progressive Neuroblastoma
Advanced Science, EarlyView.Researchers discovered that therapy‐induced loss of RD3 protein in neuroblastoma triggers a dangerous shift: cancer cells become more stem‐like, invasive, and resistant to treatment while evading immune detection. RD3 loss suppresses antigen presentation and boosts immune checkpoints, creating an immune‐silent environment.
Poorvi Subramanian +7 more
wiley +1 more source
Advanced Science, EarlyView.Upon NIR irradiation at 808 nm, the activity of TRPV4 was inhibited by M2M@BPSC, which led to reduced calcium influx, mitochondrial protection, and, importantly, the transcriptional activation of the STAT6‐EGR2 pathway. The improved macrophage function indirectly readjusts the equilibrium between C‐ECM and F‐ECM to reconstruct a suitable ...
Chenqi Yu +11 more
wiley +1 more source
Identifying Cytokine Motif‐Containing, Immunomodulatory Bacterial Proteins in Human Gut Microbiome
Advanced Science, EarlyView.By building and constructing HMM (Upper left, blue), the authors identify CMCPs in bacteria genomes and CRC related metagenomes and enriched CRC‐related CMCPs (Upper right, blue). They analyze sequence and structural similarity of hits (Lower left, green), test function with engineered EcN delivered to tumors in a mouse tumor model (Lower right, pink ...
Ziyu Wang +12 more
wiley +1 more source
Targeting Interleukin-13 Receptor α2 and EphA2 in Aggressive Breast Cancer Subtypes with Special References to Chimeric Antigen Receptor T-Cell Therapy. [PDF]
Int J Mol SciKashyap D, Salman H.
europepmc +1 more source
Targeted Therapy with a Novel Superantigen-based Fusion Protein Against Interleukin-13 Receptor α2-overexpressing Tumor Cells: An In-silico Study. [PDF]
Iran J PatholGholipour Z +2 more
europepmc +1 more source
Some of the next articles are maybe not open access.
Related searches:
Related searches:
Current Opinion in Pulmonary Medicine, 2003
Some time ago, the Th2 cytokine, interleukin (IL)-13, was identified as a critical regulator of the allergic response. Initial studies in animal models of disease provided compelling evidence that IL-13, independent from other Th2 cytokines, was necessary and sufficient to induce all features of allergic asthma.
Marsha, Wills-Karp, Monica, Chiaramonte
openaire +2 more sources
Some time ago, the Th2 cytokine, interleukin (IL)-13, was identified as a critical regulator of the allergic response. Initial studies in animal models of disease provided compelling evidence that IL-13, independent from other Th2 cytokines, was necessary and sufficient to induce all features of allergic asthma.
Marsha, Wills-Karp, Monica, Chiaramonte
openaire +2 more sources
Current Protocols in Immunology, 2001
AbstractThis unit describes two protocols that can be used to quantitate interleukin‐13 (IL‐13). The enzyme‐linked immunosorbent assay (ELISA) has the advantage of being highly specific for human IL‐13 and does not recognize other cytokines present in the sample.
Angus, Lauder, Andrew N J, McKenzie
openaire +2 more sources
AbstractThis unit describes two protocols that can be used to quantitate interleukin‐13 (IL‐13). The enzyme‐linked immunosorbent assay (ELISA) has the advantage of being highly specific for human IL‐13 and does not recognize other cytokines present in the sample.
Angus, Lauder, Andrew N J, McKenzie
openaire +2 more sources
[Interleukin 13 and interleukin 13 receptor involvement in systemic sclerosis].
La Revue de medecine interne, 2007Interleukin 13 is an immunoregulatory cytokine predominantly secreted by activated Th2 cells. It has similar functions with interleukin 4 and they share a common receptor. However, unlike interleukin 4, l'interleukin 13 does not appear to be important in the initial differentiation of CD4 T into Th2-type cells, but rather appears to be necessary in the
Granel, B., Chevillard, C., Dessein, A.
openaire +2 more sources
Interleukin-13 in asthma pathogenesis
Current Allergy and Asthma Reports, 2004Summary: Bronchial asthma is a complex disorder that is thought to arise as a result of aberrant T‐lymphocyte responses to noninfectious environmental antigens. In particular, the symptoms of asthma are closely associated with the presence of activated T‐helper 2 cell (Th2) cytokine‐producing cells [interleukin (IL)‐4, IL‐5, IL‐9, and IL‐13] in the ...
openaire +3 more sources
International Journal of Rheumatic Diseases, 2021
AbstractAim of the workTo identify the role of serum IL‐13, and its receptor subunit expressions as a serologic marker of rheumatoid arthritis (RA)‐associated ILD (RA‐ILD).Patients and MethodsFifty RA patients with ILD and 50 RA patients without ILD were examined, in addition to 50 controls.
Manal Shawky Hussein +5 more
openaire +2 more sources
AbstractAim of the workTo identify the role of serum IL‐13, and its receptor subunit expressions as a serologic marker of rheumatoid arthritis (RA)‐associated ILD (RA‐ILD).Patients and MethodsFifty RA patients with ILD and 50 RA patients without ILD were examined, in addition to 50 controls.
Manal Shawky Hussein +5 more
openaire +2 more sources