Results 241 to 250 of about 583,184 (351)

A Keratinocyte‐Mast Cell NF‐κB2/CXCL2/IL‐6 Amplification Loop Enhances Cutaneous Antifungal Defense Against C. albicans

Advanced Science, EarlyView.
ABSTRACT Mast cells (MCs), key innate immune sentinels at the host–environment interface, serve as primary responders to invading pathogens. However, their specific contribution to host defense against cutaneous Candida albicans (C. albicans) infection and their synergy with other immune and non‐immune cells remain poorly understood. Here, we show that
Yan Yuan, Manyun Mao, Jiaan Zhang, Zhimin Duan, JiaNing Wang, Yujie Chen, Sihan Chen, Chuting Liang, Xvyue Zhou, Songmei Geng, Min Li, Xu Chen, Ni Lian   +12 more
wiley   +1 more source

Relationship of serum interleukin-13 with eotaxin and airway hyperresponsiveness in atopic asthmatics

, 2003
Jie Yang, Jae Jeong Shim, Dongjune Keum
openalex   +1 more source

Increased expression of interleukin-13 but not interleukin-4 in CD4+ cells from patients with the hyper–IgE syndrome [PDF]

, 2002
K.O. Gudmundsson, O E Sigurjonsson, S. Gudmundsson, David Goldblatt, C.M.R. Weemaes, A Haraldsson   +5 more
openalex   +1 more source

Clinical significance of serum interleukin-4, interleukin-12, interleukin-13, and transforming growth factor-β levels in children with sleep-disordered breathing. [PDF]

Am J Transl Res
Du Y, Dai X, Jiang Y, Ren J, Wang Y, Jiang Y.   +5 more
europepmc   +1 more source

Legumain Restrains Granuloma Formation by Inhibiting mTORC1/STAT1‐Mediated M1 Macrophage Polarization in Sarcoidosis

Advanced Science, EarlyView.
Legumain (LGMN) is upregulated in macrophages during sarcoid‑like granuloma formation. Macrophage‑derived LGMN binds to integrin αvβ3 and suppresses mTORC1/STAT1 signaling to restrain M1 macrophage polarization. Intratracheal delivery of lipid nanoparticles carrying Lgmn plasmid DNA (pDNA) elevates LGMN expression and effectively attenuates pulmonary ...
Mengyuan Liu, Yueyin Han, Bingbing Xie, Lili Zhu, Wenxiu Xu, Yinzhen Han, Yue Liao, Shuwei Gao, Dingyuan Jiang, Jing Geng, Zhen Li, Yinan Hu, Huaping Dai   +12 more
wiley   +1 more source

Interleukin-13 Inhibitors in the Treatment of Atopic Dermatitis: The Role of Tralokinumab. [PDF]

Dermatol Pract Concept
Dattola A, Tolone M, Amore E, Bennardo L, Trovato F, Amato S, Grieco T, Richetta AG, Pellacani G, Skroza N, Nisticò SP.   +10 more
europepmc   +1 more source

Tailored Porous Bimetallic Nanozyme Platform for Full‐Cycle Therapeutics of Intestinal Ischemia/Reperfusion

Advanced Science, EarlyView.
ABSTRACT Intestinal ischemia/reperfusion (I/R) injury presents a biphasic pathology: an acute oxidative‐inflammatory phase leading to organ failure, and a recovery phase marked by mucosal dysfunction and bacterial translocation. The developed MPB@TA‐Cu‐Ma nanocomposite functions as a dual‐phase therapeutic platform with significant efficacy. It rapidly
Chenghao Qiu, Wenjing Xian, Mengxue Wang, Guozhi Zhao, Yanhuo Zhang, Zhiyu Zhou, Bo Sheng, Zhuo Zhen, Xie Liu, Shouwen Diao, Mengwei Tu, Chen Qiu, Huixian Wang, Jianbo Zhang, Peng Zhu, Tong Li   +15 more
wiley   +1 more source

Interleukin 13 and its role in gut defence and inflammation [PDF]

, 2012
Peter Mannon, Walter Reinisch
openalex   +1 more source

Urinary interleukin 13 level in steroid sensitive and resistant nephrotic syndrome: a cross-sectional single center study. [PDF]

Sci Rep
Ermian B, Samieefar N, Vahidi A, Fahimi D, Peirovi N, Aldokhi MH, Bazargani B, Abbasi A, Askarian F, Moghtaderi M.   +9 more
europepmc   +1 more source

Leveraging Macrophage Metabolic Reprogramming for Enhanced Anti‐Tumor Immunity

Advanced Science, EarlyView.
Tumor‐associated macrophages (TAMs) are key regulators of the tumor microenvironment (TME), with their metabolic states playing a critical role in tumor progression or regression. This review summarizes current understanding of TAM metabolic plasticity alongside cutting‐edge bioengineering innovations, outlining a roadmap for transforming the ...
Zhiyun Liu, Lingyao Zeng, Xulin Gan, Yilin Zhou, Han Shen, Dan Wu, Xin Shou, Minmin Jiang, Liyun Shi   +8 more
wiley   +1 more source