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Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia

open access: yesAdvanced Science, EarlyView.
FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni   +17 more
wiley   +1 more source

Relation between interleukin-13 and annexin-V levels and carotid intima-media thickness in nephrotic syndrome. [PDF]

open access: yesJ Circ Biomark
Elsehmawy AA   +9 more
europepmc   +1 more source
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Measurement of Interleukin‐13

Current Protocols in Immunology, 2001
AbstractThis unit describes two protocols that can be used to quantitate interleukin‐13 (IL‐13). The enzyme‐linked immunosorbent assay (ELISA) has the advantage of being highly specific for human IL‐13 and does not recognize other cytokines present in the sample.
Angus, Lauder, Andrew N J, McKenzie
openaire   +2 more sources

Interleukin-13 in asthma

Current Opinion in Pulmonary Medicine, 2003
Some time ago, the Th2 cytokine, interleukin (IL)-13, was identified as a critical regulator of the allergic response. Initial studies in animal models of disease provided compelling evidence that IL-13, independent from other Th2 cytokines, was necessary and sufficient to induce all features of allergic asthma.
Marsha, Wills-Karp, Monica, Chiaramonte
openaire   +2 more sources

[Interleukin 13 and interleukin 13 receptor involvement in systemic sclerosis].

La Revue de medecine interne, 2007
Interleukin 13 is an immunoregulatory cytokine predominantly secreted by activated Th2 cells. It has similar functions with interleukin 4 and they share a common receptor. However, unlike interleukin 4, l'interleukin 13 does not appear to be important in the initial differentiation of CD4 T into Th2-type cells, but rather appears to be necessary in the
Granel, B., Chevillard, C., Dessein, A.
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Interleukin-13 in asthma pathogenesis

Current Allergy and Asthma Reports, 2004
Summary:  Bronchial asthma is a complex disorder that is thought to arise as a result of aberrant T‐lymphocyte responses to noninfectious environmental antigens. In particular, the symptoms of asthma are closely associated with the presence of activated T‐helper 2 cell (Th2) cytokine‐producing cells [interleukin (IL)‐4, IL‐5, IL‐9, and IL‐13] in the ...
openaire   +3 more sources

Immunoregulatory Roles of Interleukin-13 in Cattle

Journal of Interferon & Cytokine Research, 1999
Interleukin-13 (IL-13) is produced predominantly by helper T lymphocytes of the Th2 phenotype and mediates its effects on several immune cells, including B lymphocytes and macrophages, stimulating their proliferation, differentiation, and effector functions.
W L, Trigona   +3 more
openaire   +2 more sources

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