Results 21 to 30 of about 2,171 (89)

Time‐restricted feeding mitigates Alzheimer's disease‐associated cognitive impairments via a B. pseudolongum‐propionic acid‐FFAR3 axis

iMeta, Volume 4, Issue 2, April 2025.
A 4‐month of time‐restricted feeding (TRF) intervention alleviated cognitive impairments in Alzheimer's disease (AD) patients, while a 3‐month TRF regimen improved spatial memory, reduced amyloid‐beta accumulation, and promoted microglial aggregation around plaques in AD mice. Antibiotic‐induced gut microbiota depletion partly abolished TRF's benefits.
Yihang Zhao, Mengzhen Jia, Chen Ding, Bingkun Bao, Hangqi Li, Jiabin Ma, Weixuan Dong, Rui Gao, Xuhui Chen, Jiao Chen, Xiaoshuang Dai, Yuanqiang Zou, Jun Hu, Lin Shi, Xuebo Liu, Zhigang Liu   +15 more
wiley   +1 more source

Cardiomyocyte engineering: The meeting point of transcription factors, signaling networks, metabolism and function

Acta Physiologica, Volume 241, Issue 2, February 2025.
Abstract Direct cardiac reprogramming or transdifferentiation is a relatively new and promising area in regenerative therapy, cardiovascular disease modeling, and drug discovery. Effective reprogramming of fibroblasts is limited by their plasticity, that is, their ability to reprogram, and depends on solving several levels of tasks: inducing ...
Oksana O. Piven, Raminta Vaičiulevičiūtė, Eiva Bernotiene, Pawel Dobrzyn   +3 more
wiley   +1 more source

Therapeutic Controlled Release Strategies for Human Osteoarthritis

Advanced Healthcare Materials, Volume 14, Issue 2, January 14, 2025.
Therapeutic controlled release is a promising approach to treat the progressive and irreversible pathological changes in human osteoarthritis. This strategy is based on the application of recombinant molecules, drugs, and gene sequences via biocompatible materials and may provide effective and long‐lasting tools promoting the spatiotemporal delivery ...
Dan Wang, Wei Liu, Jagadeesh K. Venkatesan, Henning Madry, Magali Cucchiarini   +4 more
wiley   +1 more source

Biomarkers in Schizophrenia: Current Approaches and New Developments—A Literature Review

Behavioural Neurology, Volume 2025, Issue 1, 2025.
Schizophrenia (SZ) is categorized as a chronic severe highly heritable brain disease. Symptoms include positive, negative, and cognitive symptoms. Despite numerous theories concerning the etiopathogenesis of SZ, the symptoms, although characteristic in their phenomenology, manifest themselves in a rather heterogeneous manner, which makes them subject ...
Alicja Sierakowska, Ewa Niewiadomska, Sebastian Łabuda, Anna Bieniasiewicz, Mateusz Roszak, Beata Łabuz-Roszak, Enzo Emanuele   +6 more
wiley   +1 more source

Fibrosis‐Encapsulated Tumoroid, A Solid Cancer Assembloid Model for Cancer Research and Drug Screening

Advanced Healthcare Materials, Volume 13, Issue 31, December 16, 2024.
The Multi‐Layer Spheroid (MLS) formation method can construct Fibrosis‐Encapsulated Tumoroids (FETs), which replicate the structural characteristics of peritumoral fibrosis, serving as a tissue‐level simulator for cancer research and drug evaluation in solid tumors.
Yeonsue Jang, Suki Kang, Hyunho Han, Chang Moo Kang, Nam Hoon Cho, Baek Gil Kim   +5 more
wiley   +1 more source

Early Adversity Affects Cerebellar Structure and Function—A Systematic Review of Human and Animal Studies

Developmental Psychobiology, Volume 66, Issue 7, November 2024.
ABSTRACT Recent research has highlighted cerebellar involvement in cognition and several psychiatric conditions such as mood and anxiety disorders and schizophrenia. Attention‐deficit/hyperactivity disorder and autism spectrum disorder have been linked to reduced cerebellar volume as well.
Annakarina Mundorf, Sarah A. Merklein, Laura C. Rice, John E. Desmond, Jutta Peterburs   +4 more
wiley   +1 more source

Publication Only

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

ePoster

European Journal of Neurology, Volume 32, Issue S1, June 2025.
wiley   +1 more source

ePosters

European Journal of Neurology, Volume 31, Issue S1, June 2024.
wiley   +1 more source

A curated list of immune system associated genes related to cancer. [PDF]

BMC Genom Data
Al-Mohannadi A, Awada Z, Lo B, Mifsud B, Deola S.   +4 more
europepmc   +1 more source