Results 151 to 160 of about 3,159,504 (378)
Advanced Healthcare Materials, EarlyView.The limitations of existing clinical treatments highlight the need for a more comprehensive strategy for addressing infected diabetic wounds. A tri‐layered scaffold is developed to deliver therapeutics loaded in CuBDC and ZIF‐8 MOFs that are tailored to the requirements of deep‐infected diabetic wounds.
Ayse Gunyakti Mujtaba +8 more
wiley +1 more source
Salivary Levels of Interleukin-17 in Iranian Patients With Systemic Sclerosis
Acta Medica IranicaSystemic sclerosis (SSc) is a rare immune-mediated rheumatic disease in which the skin, muscles, blood vessels, and internal organs are damaged through chronic inflammation.
Ali Tadayon +5 more
doaj +1 more source
Interleukin-17: A New Bone Acting Cytokine In Vitro [PDF]
, 1999 Rutger L. van Bezooijen +3 more
openalex +1 more source
Human beta defensin 2 selectively inhibits HIV-1 in highly permissive CCR6+CD4+ T cells [PDF]
, 2017 Chemokine receptor type 6 (CCR6)+CD4+ T cells are preferentially infected and depleted during HIV disease progression, but are preserved in non-progressors.
Aaron Christensen-Quick +7 more
core +1 more source
Advanced Healthcare Materials, EarlyView.Beta‐glucans have gained significant attention as an immunomodulatory biomaterial with cell‐targeting capabilities. This review comprehensively outlines the design and fabrication methods for producing beta‐glucan particles at both the micro and nanoscale and their applications in immune cell targeting, immunomodulation, and drug delivery ...
Nate Dowdall, Todd Hoare
wiley +1 more source
Targeting interleukin-17 in chronic inflammatory disease: A clinical perspective
Journal of Experimental Medicine, 2019 Although many chronic inflammatory diseases share the feature of elevated IL-17 production, therapeutic targeting of IL-17 has vastly different clinical outcomes.
P. Zwicky, S. Unger, B. Becher
semanticscholar +1 more source
A microbial symbiosis factor prevents intestinal inflammatory disease [PDF]
, 2008 Humans are colonized by multitudes of commensal organisms representing members of five of the six kingdoms of life; however, our gastrointestinal tract provides residence to both beneficial and potentially pathogenic microorganisms.
Kasper, Dennis L. +2 more
core
Rational Design of Unsaturated, Thioether Ionizable Lipids for Enhanced In Vivo mRNA Delivery
Advanced Healthcare Materials, EarlyView.Lipid nanoparticles (LNPs) have rapidly become the delivery system of choice for RNA therapeutics. Here, a rational design approach is taken to improve the effectiveness of LNPs based on an ionizable thioether lipid library. The incorporation of unsaturated tails and bulkier, hydrophobic head groups significantly enhances their functionality and ...
Eleni Samaridou +4 more
wiley +1 more source
Requirement of Tumor Necrosis Factor Receptor–Associated Factor (Traf)6 in Interleukin 17 Signal Transduction [PDF]
, 2000 Ralf Schwandner +2 more
openalex +1 more source
Advanced Materials, EarlyView.A mitochondria‐targeted cationic nanoscale metal organic framework shows strong radiotherapy‐radiodynamic therapy effects and selectively releases digitonin in acidic tumor microenvironments to induce disulfidptosis of cancer cells and downregulate immune checkpoints in cancer and T cells, thereby eliciting strong antitumor immunity to effectively ...
Wenyao Zhen +7 more
wiley +1 more source