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Interleukin-17 Cytokines and Receptors: Potential Amplifiers of Tendon Inflammation [PDF]
Interleukin (IL)-17A, a pro-inflammatory cytokine that is linked to the pathology of several inflammatory diseases, has been shown to be upregulated in early human tendinopathy and to mediate inflammatory and tissue remodelling events.
Jolet Y. Mimpen +3 more
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Immune and Inflammatory Pathways in Non-Alcoholic Steatohepatitis (NASH). An update [PDF]
Non-alcoholic steatohepatitis (NASH), also known as fatty liver disease (FLD), is a major public health problem. It is considered to be the hepatic manifestation of the metabolic syndrome.
Sorina Cezara Coste +10 more
doaj +3 more sources
Interleukin-17 receptor D (Sef) is a multi-functional regulator of cell signaling [PDF]
Interleukin-17 receptor D (IL17RD or IL-17RD) also known as Sef (similar expression to fibroblast growth factor), is a single pass transmembrane protein that is reported to regulate several signaling pathways .
Shivangi Pande +2 more
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IL17A and IL17RA gene polymorphisms in Fanconi anemia [PDF]
Fanconi anemia is a rare autosomal recessive disease. In this disease, cytokine pathways can induce the bone marrow failure that is observed in individuals with Fanconi anemia.
Rafael Zancan MOBILE +6 more
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Interleukin-17 Receptor D in Physiology, Inflammation and Cancer [PDF]
Interleukin-17 receptor D (IL-17RD) is an evolutionarily conserved member of the IL-17 receptor family. Originally identified as a negative regulator of fibroblast growth factor (FGF) signaling under the name of Sef (Similar expression to FGF genes), IL-17RD was subsequently reported to regulate other receptor tyrosine kinase signaling pathways.
Charlotte Girondel +4 more
openaire +6 more sources
ABSTRACT This research is based on a Systematic Evolution of Ligands by EXponential enrichment, also referred to as in vitro selection against the extracellular domain of human interleukin-17 receptor A (IL-17RA). Pull-down assay via quantitative polymerase chain reaction and chemiluminescence detection showed that the cloned RNA with ...
Arifur Rahman Munshi +10 more
openaire +2 more sources
The Role of Interleukin-17 in Juvenile Idiopathic Arthritis: From Pathogenesis to Treatment
Background and Objectives: Interleukin-17 (IL-17) is a cytokine family consisting of six members and five specific receptors. IL-17A was the first member to be identified in 1993.
Marino Paroli +5 more
doaj +1 more source
The interleukin-17 (IL-17) family consists of proinflammatory cytokines conserved during evolution. A comparative genomics approach was applied to examine IL-17 throughout evolution from poriferans to higher vertebrates.
Amaro Saco +4 more
doaj +1 more source
Role of High Mobility Group Box 1 and Receptor for Advanced Glycation End Products in the Periodontal Disease Pathogenesis- A Review [PDF]
Periodontitis is a multifactorial chronic inflammatory disease associated with increased secretion of several proinflammatory mediators such as Interleukin-1β (IL-1β), Interleukin-6 (IL-6), Interleukin-17 (IL-17), Tumour Necrosis Factor-α (TNF-α ...
R Ramya +3 more
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IL-13 receptors as possible therapeutic targets in diffuse intrinsic pontine glioma. [PDF]
Diffuse intrinsic pontine glioma (DIPG) is a universally fatal childhood cancer of the brain. Despite the introduction of conventional chemotherapy and radiotherapy, improvements in survival have been marginal and long-term survivorship is uncommon. Thus,
Noah E Berlow +12 more
doaj +1 more source

