Results 1 to 10 of about 442,994 (306)

Interleukin-17 Cytokines and Receptors: Potential Amplifiers of Tendon Inflammation [PDF]

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
Interleukin (IL)-17A, a pro-inflammatory cytokine that is linked to the pathology of several inflammatory diseases, has been shown to be upregulated in early human tendinopathy and to mediate inflammatory and tissue remodelling events.
Jolet Y. Mimpen   +3 more
doaj   +3 more sources

Immune and Inflammatory Pathways in Non-Alcoholic Steatohepatitis (NASH). An update [PDF]

open access: yesJournal of Mind and Medical Sciences, 2019
Non-alcoholic steatohepatitis (NASH), also known as fatty liver disease (FLD), is a major public health problem. It is considered to be the hepatic manifestation of the metabolic syndrome.
Sorina Cezara Coste   +10 more
doaj   +3 more sources

Interleukin-17 receptor D (Sef) is a multi-functional regulator of cell signaling [PDF]

open access: yesCell Communication and Signaling, 2021
Interleukin-17 receptor D (IL17RD or IL-17RD) also known as Sef (similar expression to fibroblast growth factor), is a single pass transmembrane protein that is reported to regulate several signaling pathways .
Shivangi Pande   +2 more
doaj   +3 more sources

IL17A and IL17RA gene polymorphisms in Fanconi anemia [PDF]

open access: yesBrazilian Oral Research, 2023
Fanconi anemia is a rare autosomal recessive disease. In this disease, cytokine pathways can induce the bone marrow failure that is observed in individuals with Fanconi anemia.
Rafael Zancan MOBILE   +6 more
doaj   +1 more source

Interleukin-17 Receptor D in Physiology, Inflammation and Cancer [PDF]

open access: yesFrontiers in Oncology, 2021
Interleukin-17 receptor D (IL-17RD) is an evolutionarily conserved member of the IL-17 receptor family. Originally identified as a negative regulator of fibroblast growth factor (FGF) signaling under the name of Sef (Similar expression to FGF genes), IL-17RD was subsequently reported to regulate other receptor tyrosine kinase signaling pathways.
Charlotte Girondel   +4 more
openaire   +6 more sources

SELEX-discovered aptamer that inhibits cellular interleukin-17/interleukin-17 receptor interaction and antagonizes interleukin-17 signaling

open access: yesBioscience, Biotechnology, and Biochemistry, 2023
ABSTRACT This research is based on a Systematic Evolution of Ligands by EXponential enrichment, also referred to as in vitro selection against the extracellular domain of human interleukin-17 receptor A (IL-17RA). Pull-down assay via quantitative polymerase chain reaction and chemiluminescence detection showed that the cloned RNA with ...
Arifur Rahman Munshi   +10 more
openaire   +2 more sources

The Role of Interleukin-17 in Juvenile Idiopathic Arthritis: From Pathogenesis to Treatment

open access: yesMedicina, 2022
Background and Objectives: Interleukin-17 (IL-17) is a cytokine family consisting of six members and five specific receptors. IL-17A was the first member to be identified in 1993.
Marino Paroli   +5 more
doaj   +1 more source

The Evolution and Diversity of Interleukin-17 Highlight an Expansion in Marine Invertebrates and Its Conserved Role in Mucosal Immunity

open access: yesFrontiers in Immunology, 2021
The interleukin-17 (IL-17) family consists of proinflammatory cytokines conserved during evolution. A comparative genomics approach was applied to examine IL-17 throughout evolution from poriferans to higher vertebrates.
Amaro Saco   +4 more
doaj   +1 more source

Role of High Mobility Group Box 1 and Receptor for Advanced Glycation End Products in the Periodontal Disease Pathogenesis- A Review [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2022
Periodontitis is a multifactorial chronic inflammatory disease associated with increased secretion of several proinflammatory mediators such as Interleukin-1β (IL-1β), Interleukin-6 (IL-6), Interleukin-17 (IL-17), Tumour Necrosis Factor-α (TNF-α ...
R Ramya   +3 more
doaj   +1 more source

IL-13 receptors as possible therapeutic targets in diffuse intrinsic pontine glioma. [PDF]

open access: yesPLoS ONE, 2018
Diffuse intrinsic pontine glioma (DIPG) is a universally fatal childhood cancer of the brain. Despite the introduction of conventional chemotherapy and radiotherapy, improvements in survival have been marginal and long-term survivorship is uncommon. Thus,
Noah E Berlow   +12 more
doaj   +1 more source

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