Inflammasomes: caspase-1-activating platforms with critical roles in host defense [PDF]
Activation of the inflammatory cysteine protease caspase-1 in inflammasome complexes plays a critical role in the host response to microbial infections.
Lieselotte eVande Walle +3 more
core +2 more sources
Interleukin 18 expression in the primary breast cancer tumour tissue [PDF]
Aim To investigate the presence and expression levels of the IL-18 in the primary breast cancer tissue in relation to the unchangedbreast tissue in same patients and the breast tissue in patients withbenign breast disease, as well as the correlation ...
Nahida Srabović +4 more
doaj
Interleukin-18 expression increases in response to neurovascular damage following soman-induced status epilepticus in rats [PDF]
BACKGROUND: Status epilepticus (SE) can cause neuronal cell death and impaired behavioral function. Acute exposure to potent acetylcholinesterase inhibitors such as soman (GD) can cause prolonged SE activity, micro-hemorrhage and cell death in the ...
Erik A. Johnson +4 more
core +1 more source
Introduction of Interleukin-18 genotype as a risk factor for allergic rhinitis in Chaharmahal va Bakhtiari province [PDF]
زمینه و هدف: اینترلوکین 18 عضوی از خانواده ی اینترلوکین یک می باشد که در اصل به عنوان فاکتور القا کننده ی اینترفرون گاما شناخته شده؛ ولی در تعادل واکنش های ایمنی مربوط به سلول های کمکی 1 و 2 (Th1/Th2) نیز موثر است.
Hashemzade-Chaleshtori, M. +3 more
core
Background& Objectives: Nowadays, not only obesity but also a low body mass index (BMI) may be a risk factor for cardiovascular disease. The purpose of this study was to evaluate the effect of 4 weeks of circuit resistance training with and Medicago ...
Masoumeh Habibian +2 more
doaj
ObjectiveTo evaluate the combined effects of azithromycin and varying concentrations of cyclosporin on peripheral blood mononuclear cells (PBMCs) under lipopolysaccharide (LPS) stimulation.Materials and methodsPBMCs were isolated from four healthy donors
Norah Alotaibi +7 more
doaj +1 more source
Alternative splicing of human prostaglandin G/H synthase mRNA and evidence of differential regulation of the resulting transcripts by transforming growth factor beta 1, interleukin 1 beta, and tumor necrosis factor alpha. [PDF]
Prostaglandin G/H synthase (PGG/HS) is the rate-limiting enzyme in the conversion of arachidonic acid to prostaglandins and thromboxanes. We screened a human lung fibroblast cDNA library with an ovine PGG/HS cDNA and isolated a 2.3-kilobase clone (HCO-T9)
Diaz, Arturo +2 more
core +1 more source
Background and Aim: Limited studies have been focused on the role of IL-33 and IL-18 in Rheumatoid arthritis (RA).This study was done to measure the levels of IL-18 and IL-33 in the serum of patients with RA, before treatment, three month after ...
Ali Shahraki +3 more
doaj
Rapid onset of hypercalcemia from high-grade lymphoma in the setting of HIV-related immune reconstitution inflammatory syndrome. [PDF]
Hypercalcemia in HIV patients has been previously reported, but 1,25-(OH)2 vitamin D-mediated hypercalcemia, due to increased activity of extrarenal 1-alpha hydroxylase, is rarely described with HIV-related infections or malignancies.
Bikle, Daniel +5 more
core
Association of the IL-10 and IL-18 polymorphisms with nasopharyngeal carcinoma risk
ObjectiveTo evaluate the possible association of the cytokine polymorphisms with the risk of nasopharyngeal carcinoma (NPC).MethodsWe performed a comprehensive search of electronic databases from PubMed, Web of Science, Embase, and CNKI. Articles related
Xueru Chen +14 more
doaj +1 more source

