Results 61 to 70 of about 579,902 (183)
A Meta-Analysis of Genome-Wide Association Scans Identifies IL18RAP, PTPN2, TAGAP, and PUS10 As Shared Risk Loci for Crohn's Disease and Celiac Disease [PDF]
, 2011 This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
Annese, V +17 more
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Jurnal Kedokteran dan KesehatanThe use of antipsychotic therapy is effective in managing symptoms and has become a cornerstone in the treatment of patients with schizophrenia. However, antipsychotics have side effects on the immune system, particularly affecting Interleukin 18 (IL-18)
Dita Hasni +2 more
doaj +1 more source
Linchuang shenzangbing zazhi, 2021 Objective To explore the serum expressions of interleukin-9（IL-9）,interleukin-18（IL-18）and interleukin-32（IL-32）in patients with multiple myeloma（MM）and examine their values in predicting renal injury.Methods Seventy-eight MM patients from January 2015 ...
Zhuang Ni-la +5 more
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Global Heart, 2023 Background: Previous observational studies have confirmed the relationship between inflammation and acute myocardial infarction (AMI), but genetic evidence is still lacking.
Yaxi Chen, Ling Zeng
doaj +1 more source
Genetic Variation in the IL-6 and HLA-DQB1 Genes Is Associated with Spontaneous Clearance of Hepatitis C Virus Infection. [PDF]
, 2016 Background. Millions of people are infected with hepatitis C virus (HCV) worldwide and 30% spontaneously clear the infection. Reasons for HCV clearance without antiviral treatment are not well understood. Methods.
Belitskaya-Lévy, Ilana +8 more
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Association of
Reproductive Biology and Endocrinology, 2012 Background Interleukin (IL)-18 is an important regulator of innate and acquired immune responses and has multiple roles in chronic inflammation and autoimmune disorders. Obesity is characterized by low- grade chronic inflammation.
Kim Hye-Lin +11 more
doaj +1 more source
Cross-disease innate gene signature: Emerging diversity and abundance in RA comparing to SLE and SSc [PDF]
, 2019 Overactivation of the innate immune system together with the impaired downstream pathway of type I interferon-responding genes is a hallmark of rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), and systemic sclerosis (SSc).
Fillerová, Regina +8 more
core +1 more source
Interleukin 18–independent engagement of interleukin 18 receptor-α is required for autoimmune inflammation [PDF]
Nature Immunology, 2006 T helper type 1 (T(H)1) lymphocytes are considered to be the main pathogenic cell type responsible for organ-specific autoimmune inflammation. As interleukin 18 (IL-18) is a cofactor with IL-12 in promoting T(H)1 cell development, we examined the function of IL-18 and its receptor, IL-18R, in autoimmune central nervous system inflammation.
Gutcher, I +4 more
openaire +4 more sources
Clinical Trials of Immunogene Therapy for Spontaneous Tumors in Companion Animals [PDF]
, 2014 Despite the important progress obtained in the treatment of some pets’ malignancies, new treatments need to be developed. Being critical in cancer control and progression, the immune system’s appropriate modulation may provide effective therapeutic ...
Finocchiaro, Liliana Maria Elena +1 more
core +4 more sources
طب جانباز, 2014 Aims: Exposure to mustard gas leads to acute and chronic toxic effects on the skin. Results from several studies have been suggested the role of immune mediators, including Interleukin-18, in the pathogenesis of diseases associated with the urticaria ...
N. Askari +4 more
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