Results 81 to 90 of about 161,071 (201)
Mitoprotective effect of the receptor antagonist interleukin-1 in experimental cerebral stroke
Mitoprotective activity of the receptor antagonist of interleukin-1 ( RAIL-1, 7,5 mg/kg) comparing to Thiotriazoline (50 mg/kg) was studied on the model of experimental photoinduced cerebral thrombosis in rats.
E. V. Suprun
doaj +1 more source
Evolving clinical profile of IL-1β, IL-10 and CTLA-4 gene in rheumatoid factor positive Caucasian population [PDF]
Rheumatoid arthritis (RA), a systemic autoimmune condition, causes joint damage and sometimes extra-articular lesions (cutaneous vasculitis, neuropathy, Felty’s syndrome, pericarditis, intersticial lung disease) that may be life threatening.
Anupama Sharma, Ajay kumar Singh, Sanjeev kumar Singh, Neelima Singh, Varsha Gupta, Int J Cur Bio Med Sci.
core
The gut-brain axis, BDNF, NMDA and CNS disorders [PDF]
Gastro-intestinal (GI) microbiota and the ‘gut-brain axis’ are proving to be increasingly relevant to early brain development and the emergence of psychiatric disorders.
Maqsood, Raeesah, Stone, Trevor W.
core +1 more source
The safety of interleukin-1 receptor antagonist (anakinra) in the treatment of rheumatoid arthritis
The safety profile of interleukin-1 receptor antagonist (anakinra) has been studied with randomised, placebo-controlled trials involving 2932 patients affected by rheumatoid arthritis.
L. Riente
doaj +1 more source
Objectives: β-cell dysfunction and apoptosis associated with islet inflammation play a key role in the pathogenesis of type 2 diabetes (T2D). Growing evidence suggests that islet amyloid, formed by aggregation of human islet amyloid polypeptide (hIAPP ...
Queenie Hui +6 more
doaj +1 more source
Interleukin (IL)-25, which is a member of the IL-17 family of cytokines, induces production of such Th2 cytokines as IL-4, IL-5, IL-9 and/or IL-13 by various types of cells, including Th2 cells, Th9 cells and group 2 innate lymphoid cells (ILC2).
Yasuharu Abe +8 more
doaj +1 more source
Pathogenesis of polymyalgia rheumatica [PDF]
Polymyalgia rheumatica (PMR) is a chronic, inflammatory disorder of unknown cause, almost exclusively occurring in people aged over 50 and often associated with giant cell arteritis.
Ciccia F. +4 more
core +1 more source
Serum amyloid A primes microglia for ATP-dependent interleukin-1\u3b2 release [PDF]
Acute-phase response is a systemic reaction to environmental/inflammatory insults and involves production of acute-phase proteins, including serum amyloid A (SAA).
A Basu +82 more
core +2 more sources
Background Interleukin-1 (IL-1) is a cytokine involved in the initiation and amplification of the defence response in infectious and inflammatory diseases.
Tagliabue Aldo +10 more
doaj +1 more source

