Results 111 to 120 of about 46,140 (235)

Canonical and Novel Non-Canonical Cholinergic Agonists Inhibit ATP-Induced Release of Monocytic Interleukin-1β via Different Combinations of Nicotinic Acetylcholine Receptor Subunits α7, α9 and α10

open access: yesFrontiers in Cellular Neuroscience, 2017
Recently, we discovered a cholinergic mechanism that inhibits the adenosine triphosphate (ATP)-dependent release of interleukin-1β (IL-1β) by human monocytes via nicotinic acetylcholine receptors (nAChRs) composed of α7, α9 and/or α10 subunits ...
Anna Zakrzewicz   +17 more
doaj   +1 more source

Epileptogenesis after prolonged febrile seizures: mechanisms, biomarkers and therapeutic opportunities. [PDF]

open access: yes, 2011
Epidemiological and recent prospective analyses of long febrile seizures (FS) and febrile status epilepticus (FSE) support the idea that in some children, such seizures can provoke temporal lobe epilepsy (TLE).
Alheim   +134 more
core   +1 more source

Cartilage stem/progenitor cells are activated in osteoarthritis via interleukin-1β/nerve growth factor signaling [PDF]

open access: yes, 2015
Introduction: Interleukin-1β (IL-1β) and nerve growth factor (NGF) are key regulators in the pathogenesis of inflammatory arthritis; specifically, IL-1β is involved in tissue degeneration and NGF is involved in joint pain.
Hu, C   +6 more
core   +3 more sources

The Effect of Conventional Immunosuppressive Therapy on Cytokine Serum Levels in Pemphigus Vulgaris Patients

open access: yesIranian Journal of Allergy, Asthma and Immunology, 2014
Pemphigus vulgaris is an autoimmune disease, in which the role of Th17 cytokines needs to be further explored. This study was performed to assess serum levels of three interleukins (IL) required for Th17 differentiation (IL-1β, IL-6 and IL-23) and two ...
Hossein Mortazavi   +6 more
doaj  

Expression of cannabinoid receptors in human osteoarthritic cartilage: implications for future therapies [PDF]

open access: yes, 2016
Introduction: Cannabinoids have shown to reduce joint damage in animal models of arthritis and reduce matrix metalloproteinase expression in primary human steoarthritic (OA) chondrocytes. The actions of cannabinoids are mediated by a number of receptors,
Bunning, Rowena A.D.   +4 more
core   +1 more source

Influence of supragingival biofilm control and smoking habit on Interleukin-1β concentration

open access: yesBrazilian Oral Research, 2015
This investigation compared gingival crevicular fluid (GCF) interleukin-1β (IL-1β) concentrations in periodontitis patients subjected to a strict supragingival biofilm control (Supra) for 6 months.
Sabrina Carvalho GOMES   +5 more
doaj   +1 more source

Identification of the Cytokines, Growth Factors and Their Receptors Expressed by Human Blood Eosinophils: A Transcriptomics Approach

open access: yes
Clinical &Experimental Allergy, Volume 55, Issue 12, Page 1247-1250, December 2025.
Stephane Esnault   +10 more
wiley   +1 more source

Association of interleukin-1 gene cluster polymorphisms and haplotypes with multiple sclerosis in an Iranian population

open access: yes, 2015
Multiple sclerosis (MS) is a multi-factorial autoimmune disease of the central nervous system. The exact etiology of MS is still unknown. Due to the important roles that cytokines play as mediators in immune and inflammatory responses, we have evaluated ...
Ebadi, H.   +5 more
core   +1 more source

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