Results 11 to 20 of about 23,391 (181)

Contribution of interleukin-1beta in neuropathic pain

Chinese Journal of Contemporary Neurology and Neurosurgery, 2013
Interleukin-1beta (IL-1β), a pro-inflammatory cytokine, has been implicated in the development of peripheral and central sensitization that is charactistic of neuropathic pain.
Wei GUO
doaj   +1 more source

Periodontal diseases and adverse pregnancy outcomes. Present and future

Periodontology 2000, EarlyView., 2023
Abstract For more than two decades the possible association between periodontal diseases and adverse pregnancy outcomes has been extensively evaluated. Numerous observational, intervention, and mechanistic studies have offered valuable information on this topic.
Yiorgos A. Bobetsis, Mark Ide, Mervi Gürsoy, Phoebus N. Madianos   +3 more
wiley   +1 more source

The role of the host—Neutrophil biology

Periodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple, Josefine Hirschfeld, Alpdogan Kantarci, Asaf Wilensky, Lior Shapira   +4 more
wiley   +1 more source

The Association Between Shift Work and Immunological Biomarkers in Nurses

Frontiers in Public Health, 2020
Objectives: Shift work is associated with several negative health effects. The underlying pathophysiological mechanisms are unclear, but low-grade inflammation has been suggested to play a role.
Bjørn Bjorvatn, Bjørn Bjorvatn, John Axelsson, John Axelsson, Ståle Pallesen, Ståle Pallesen, Siri Waage, Siri Waage, Øystein Vedaa, Øystein Vedaa, Kjersti M. Blytt, Kjersti M. Blytt, Hogne V. Buchvold, Bente E. Moen, Eirunn Thun   +14 more
doaj   +1 more source

Osteoprotegerin mediates tumor-promoting effects of Interleukin-1beta in breast cancer cells. [PDF]

Mol Cancer, 2017
It is widely recognized that inflammation promotes breast cancer invasion and metastasis. Given the complex nature of the breast tumor inflammatory microenvironment, much remains to be understood of the molecular mechanisms that govern these effects.
Chung ST, Geerts D, Roseman K, Renaud A, Connelly L.   +4 more
europepmc   +7 more sources

IL-1beta processing in host defense: beyond the inflammasomes. [PDF]

PLoS Pathogens, 2010
Stimulation and release of proinflammatory cytokines is an essential step for the activation of an effective innate host defense, and subsequently for the modulation of adaptive immune responses.
Mihai G Netea, Anna Simon, Frank van de Veerdonk, Bart-Jan Kullberg, Jos W M Van der Meer, Leo A B Joosten   +5 more
doaj   +1 more source

Maltol, a Natural Flavor Enhancer, Inhibits NLRP3 and Non-Canonical Inflammasome Activation

Antioxidants, 2022
Maltol (3-hydroxy-2-methyl-4-pyrone) is used widely as a food and cosmetic supplement, and it has antioxidant and anti-inflammatory activities. Inflammasome causes the maturation and secretion of interleukin (IL)-1β and -18 through the activation of ...
Huijeong Ahn, Gilyoung Lee, Byung-Cheol Han, Seung-Ho Lee, Geun-Shik Lee   +4 more
doaj   +1 more source

In vivo effect of interleukin-1beta and interleukin-1RA on oocyte cytoplasmic maturation, ovulation, and early embryonic development in the mare

Reproductive Biology and Endocrinology, 2005
A growing body of evidence suggests that the interleukin-1 system is involved in periovulatory events. Previous work from our lab demonstrated that in the mare, interleukin-1beta (IL-1beta) increases the ovulatory rate of metaphase II oocytes.
Gérard Nadine, Duchamp Guy, Caillaud Maud   +2 more
doaj   +1 more source

Systemic infection, interleukin 1beta, and cognitive decline in Alzheimer's disease [PDF]

Journal of Neurology, Neurosurgery & Psychiatry, 2003
Activated microglia, the resident macrophages of the brain, are a feature of Alzheimer's disease. Animal models suggest that when activated microglia are further activated by a subsequent systemic infection this results in significantly raised levels of interleukin 1beta within the CNS, which may in turn potentiate neurodegeneration.
Holmes, C., El-Okl, M., Williams, A.L., Cunningham, C., Wilcockson, D., Perry, V.H.   +5 more
openaire   +3 more sources

Degradation of Interleukin 1β by Matrix Metalloproteinases [PDF]

Journal of Biological Chemistry, 1996
Matrix metalloproteinases (MMPs) and interleukin 1 (IL-1) are implicated in inflammation and tissue destruction, where IL-1 is a potent stimulator of connective tissue cells to produce the extracellular matrix-degrading MMPs. Here, we report that IL-1beta, but not IL-1alpha, is degraded by MMP-1 (interstitial collagenase), MMP-2 (gelatinase A), MMP-3 ...
Ito, A, Mukaiyama, A, Itoh, Y, Nagase, H, Thøgersen, Ida, Enghild, J J, Sasaguri, Y, Mori, Y   +7 more
openaire   +3 more sources