Results 41 to 50 of about 242,716 (208)

Relationship between IL-1β production and endodontic status of human periapical lesions [PDF]

Vojnosanitetski Pregled, 2017
Background/Aim. Apical periodontitis is mainly caused by bacterial infection within the root canal and periapical bone destruction which are prominent features of this lesion.
Popovska Lidija, Dimova Cena, Evrosimoska Biljana, Stojanovska Vera, Muratovska Ilijana, Cetenović Bojana, Marković Dejan   +6 more
doaj   +1 more source

Cysteine redox potential determines pro-inflammatory IL-1beta levels.

PLoS ONE, 2009
BackgroundCysteine (Cys) and its disulfide, cystine (CySS) represent the major extracellular thiol/disulfide redox control system. The redox potential (E(h)) of Cys/CySS is centered at approximately -80 mV in the plasma of healthy adults, and oxidation ...
Smita S Iyer, Carolyn J Accardi, Thomas R Ziegler, Roberto A Blanco, Jeffrey D Ritzenthaler, Mauricio Rojas, Jesse Roman, Dean P Jones   +7 more
doaj   +1 more source

Uric acid is independently associated with interleukin‐1β levels in tear fluid of hyperuricemia and gout patients

Immunity, Inflammation and Disease, 2023
Objectives To explore pro‐inflammatory cytokines status in the tear fluid of patients with hyperuricemia and gout and its association with uric acid level.
Mian Wu, Xingna Hu, Ting Lu, Chenxiao Liu, Honghong Lu   +4 more
doaj   +1 more source

Association analysis between variants of the interleukin-1beta and the interleukin-1 receptor antagonist gene and antidepressant treatment response in major depression

, 2008
This study investigated the possible association of the interleukin-1 beta (IL-1beta) C-511T promoter polymorphism and the interleukin-1 receptor antagonist (IL-1Ra) (86bp)(n) variable number of tandem repeats (VNTR) polymorphism with antidepressant ...
Tadic, A, Kohnen, R, Dahmen, N, Müller, M J, Stassen, H H, Szegedi, A, Rujescu, Dan   +6 more
core   +1 more source

Arthrogenic human synovial cysts: immunohistochemical profile of interleukin-1beta, interleukin-6, tumour necrosis factor-alpha

Folia Morphologica, 2021
BACKGROUND: Synovial cysts are currently classified as degenerative lesions affecting the joint capsule or adjacent structures. MATERIALS AND METHODS: In our study we describe the results obtained in an immunohistochemical study comprising 18 patients ...
S. Taurone, M. T. Santarelli, C. De Ponte, L. Bardella, M. Ralli, C. Morselli, A. Nicolai, A. Greco, A. Ferretti, M. Artico   +9 more
doaj   +1 more source

NLRP3/cryopyrin is necessary for interleukin-1beta (IL-1beta) release in response to hyaluronan, an endogenous trigger of inflammation in response to injury.

, 2009
Inflammation under sterile conditions is a key event in autoimmunity and following trauma. Hyaluronan, a glycosaminoglycan released from the extracellular matrix after injury, acts as an endogenous signal of trauma and can trigger chemokine release in ...
Grant, Ethan P, Amirhossein Misaghi, Kenshi Yamasaki, Kristen R. Taylor, Hoffman, Hal M, Richard L. Gallo, Taylor, Kristen R, Audish, David, Bertin, John, Jun Muto, Hal M. Hoffman, Anna L. Cogen, David Audish, John Bertin, Coyle, Anthony J, Misaghi, Amirhossein, Cogen, Anna L, Muto, Jun, Yamasaki, Kenshi, Gallo, Richard L, Anthony J. Coyle, Ethan P. Grant   +21 more
core   +1 more source

Production of interleukin 1beta by human hematopoietic progenitor cells. [PDF]

Journal of Clinical Investigation, 1996
The production of interleukin 1beta (IL-1beta) by human hematopoietic stem/progenitor cells was studied to explore the concept that these cells are not merely responders to stimuli from their microenvironment, but can themselves produce a powerful biomodulator.
K, Watari, H, Mayani, F, Lee, W, Dragowska, P M, Lansdorp, J W, Schrader   +5 more
openaire   +2 more sources

Evaluation of interleukin -1B (+3954) gene polymorphism in patients with chronic and aggressive periodontitis: A genetic association study

Contemporary Clinical Dentistry, 2012
Background: IL-1 cytokines have central roles in the pathogenesis of periodontal disease. Polymorphism in the locus +3954 (C/T) of the human IL-1B gene has been shown to affect the levels of this cytokine.
Sujata S Masamatti, Ashish Kumar, Tarun Kumar A Baron, Dhoom S Mehta, Kishore Bhat   +4 more
doaj   +1 more source

Single nucleotide polymorphisms in IL-1A RS1800587, IL-1B RS1143634 and vitamin D receptor rs731236 in stage III grade B/C periodontitis

Balkan Journal of Medical Genetics, 2023
The purpose of the study is to determine the prevalence of interleukin (IL)-1A (rs1800587), IL-1B (rs1143634) and vitamin D receptor (VDR) (TaqI, rs731236) gene polymorphisms in the Turkish population and their association with Stage III Grade B/C ...
Özturk Özener H., Tacal Aslan B., Eken B.F., Agrali Ö.B., Yildrim H.S., Altunok E.Ç., Ulucan K., Kuru L.   +7 more
doaj   +1 more source

ROS‐Responsive Eye Drop for Controlled Release of 20‐Deoxyingenol Improves Diabetic Corneal Healing by Activating Macrophage Autophagy and Metabolic Reprogramming

Advanced Science, EarlyView.
Schematic illustration of ROS‐responsive TSPBA‐PVA microspheres loaded with 20‐deoxyingenol (TP/20‐DOI) for diabetic corneal wound healing: (a) fabrication and ROS‐triggered release; (b) autophagy activation and metabolic reprogramming in macrophages; (c) suppression of macrophage‐derived CXCL3/CXCL5, attenuation of neutrophil infiltration, and ...
Jiaxin Wu, Wanying Chen, Haijiang Qiu, Weihan Zheng, Ying Jiao, Jingheng Du, Zhudan Zhuang, Xing Hua, Jingyi Gu, Yuheng Liu, Zhaojin Li, Jingbin Xie, Hanxiao Sun, Huifei Lan, Xin Sun, Yunxia Xue, Ting Fu, Zhijie Li, Guobing Chen, Shiyu Li, Jun Liu   +20 more
wiley   +1 more source