Results 51 to 60 of about 242,716 (208)
ACSL4‐Dependent Lysosomal Lipid Peroxidation Links WTAP‐Mediated m6A Modification to Intervertebral Disc Degeneration
Advanced Science, EarlyView.IL‐1β upregulates the protein level of WTAP, which promotes the m6A modification of ACSL4 mRNA in an IGF2BP2‐dependent manner, thereby enhancing its stability. The increased ACSL4 drives lipid peroxidation, leading to lysosomal membrane permeabilization (LMP) and impaired mitophagy, which collectively accelerate intervertebral disc degeneration (IVDD). Shu Jia, Xu Gao, Laimin Zhu, Haixia Song, Jing Wu, Shang Chen, Sheng Gao, Lu Zhang, Chunyang Meng +8 morewiley +1 more sourceCardiometabolic effects of genetic upregulation of the interleukin 1 receptor antagonist : a Mendelian randomisation analysis [PDF]
, 2015 Funded by: UK Medical Research Council, British Heart Foundation, UK National Institute for Health Research, National Institute for Health Research Cambridge Biomedical Research Centre, European Research Council, and European Commission Framework ...D. F. Easton (7608179), Howson, Joanna M M, Singleton, A, E. Harshfield (7646096), Sanna, Serena, Hall, A.S. (Alistair), Bown, Matthew J, Stefánsson, K., Staley, James R, Dunlop, M., Rasmussen-Torvik, L.J. (Laura), B. G. Nordestgaard (7605362), Langefeld, C.D. (Carl), Grande, P, Sanna, S., Smith, AV, G. F. Mitchell (7646183), Kooner, J.S. (Jaspal S.), Felix, J.F., Gudnasson, Vilmundur, Carrell, D. S., McCarty, Catherine A., D. Crossman (7646276), Hakonarson, Hakon, Franco, O.H., Stefansson, K, Nelson, C.P. (Christopher P.), Walston, J. (Jeremy), Eisen, T. (Timothy), Hofman, A., Crosslin, D.R., Assimes, T, D. T. Bishop (7646264), de Bakker, Paul I. W., Gorski, M. (Mathias), Malinowski, J. (Jennifer), G. Tromp (7646132), Li, Yong, Goldschmidt, Hartmut, Y. Wang (473169), M. Sudman (7646219), Ferreira, MA, Crawford, DC, Weidinger, S., T. Kessler (7646111), Nielsen, SF, E. Di Angelantonio (7611773), McCarty, C.A. (Catherine A.), O. Gottesman (7646165), März, Winfried, Gorski, Mathias, Hall, AS, J. R. Staley (7646090), Iles, M.M., Hayward, NK, Hopewell, J. C., Peissig, P.L., Brown, Matthew J., Bevan, S, P. Willeit (7605167), Nordestgaard, B.G., L. A. Lange (7646105), Kessler, Thorsten, Delgado, G.E., Law, M. H., Delgado, G., Franceschini, N. (Nora), Nalls, M.A., Zhang, W., Hopewell, Jemma C., Harshfield, E, Delgado, G. E., Franco, O. H., N. J. Timpson (7608851), Tracy, Russell, Franceschini, N, Delgado, GE, H. Baurecht (7646204), M. de Andrade (7646150), Butterworth, Adam S, Bown, M.J., Polychronakos, C. (Constantin), Kooner, J.S., Schunkert, H, A. F. Baas (7646126), Li, Yunlei, Nalls, M.A. (Michael), N. J. Samani (7591811), Peissig, Peggy L., Bown, MJ, de Andrade, Mariza, Wareham, N.J., Nelson, CP, Scott, Robert A., Li, Y., Nejentsev, S., Allan, JM, M. Gorski (7626956), Evans, D.M. (David M.), Van 'T Hof, F.N.G. (Femke), A. A. S. Majumder (7646297), Erdmann, Jeanette, Samani, N. J., Rader, D.J. (Daniel), Harshfield, E., Houlston, R.S., Delgado, Graciela E., S. S. Verma (7646141), Franke, Andre, E. Zeggini (7632767), Zhang, WH, A. Singleton (7646228), Polychronakos, C, Franke, A, U. Thorsteinsdottir (7606031), S. G. Thompson (7646303), M. F. Keller (7646189), J. P. Bradfield (7646234), de Bakker, Paul I W, Allan, J. M., van 't Hof, Femke N. G., D. Chubb (7646255), Nikpay, Majid, M. A. Brown (1916698), Dehghan, Abbas, J. S. Kooner (7605356), Eisen, T, Chubb, Daniel, Harshfield, Eric, Whiffin, N, Freitag, Daniel, H. S. Markus (7626758), Tomlinson, I.P., Goldschmidt, H, Erdmann, J, Baas, A.F., Lange, Leslie A., Nielsen, S. F., Weidinger, S. (Stephan), Farrall, M. (Martin), Kuivaniemi, Helena, Ganesh, Santhi K., Reilly, Muredach, März, W. (Winfried), Huang, J., C. P. Nelson (7591670), Qu, Liming, Thorsteinsdottir, U, Wood, Angela M., De Andrade, M, Ritchie, M.D., Gottesman, O., Kastrati, A, Young, R. (Robin), J. M. Allan (7646246), Young, R., Müller-Nurasyid, M., van ‘t Hof, Femke N.G., Thorsteinsdottir, U. (Unnur), Psaty, B. M., J. Malinowski (7646147), Mueller-Nurasyid, M, Psaty, B.M. (Bruce), Easton, Douglas F., Hakonarson, H, Burgess, S, Ramond, A. (Anna), Marz, W, Luo, Y. (Yang), Pacheco, Jennifer A., Ritchie, Marylyn D., Carrell, D.S. (David), Howson, Joanna M.M., Ho, W.K., Kathiresan, S. (Sekar), S. A. Lubitz (7646210), Spackman, S, Smith, Nicholas L., Hemminki, Kari, Burgess, Stephen, D. C. Crawford (7646144), S. Nejentsev (7646273), D. Thompson (1262301), S. F. Nielsen (7646099), Bevan, S., Kooner, J. S., van 't Hof, F.N.G., Langefeld, Carl D., Lange, Leslie A, Lubitz, S.A. (Steven), Harris, T.B. (Tamara B.), Thompson, D., Sweeting, M, Iles, MM, Bown, M.J. (Matthew), M. Reilly (7609133), Ho, WK, Houlston, Richard S., Houlston, R. S., Ala-Korpela, M. (Mika), Li, Y. (Yong), Verma, S. S., Gottesman, Omri, A. Parsa (7626662), S. D. Thompson (7646222), Tomlinson, I.P. (Ian), J. Kettunen (7646180), Markus, H. S., Franco, O.H. (Oscar), Baas, A. F., Psaty, Bruce M., Ferreira, Manuel A., Jones, G. T., Grande, Peer, Smith, N.L., Al Shafi Majumder, A. (Abdullah), Law, MH, Wang, YF, S. Spackman (7646087), A. V. Smith (7605131), Hemminki, Kari,, Hall, A. S., Dunlop, Malcolm, Panoutsopoulou, K. (Kalliope), Howson, J. M. M., M. M. Iles (7646261), Allan, J.M., Tybjaerg-Hansen, A. (Anne), J. C. Bis (7625957), Ferreira, M.A., Freitag, DF, Matthew James Bown (7632455), Allan, James M., Jones, G.T., Wang, Y., Y. Li (696089), Franke, A., Parsa, Afshin, Bis, J.C. (Joshua), Hall, Alistair S., Farrall, M, Barbalic, M., Gottesman, R.F. (Rebecca), Hayward, N. K., Crosslin, D. R., van Rij, A., Staley, James R., Collins, F.S. (Francis), Porcu, E., Pacheco, J. A., Wang, Y, Lange, L. A., Henrion, Marc, Keller, MF, Zeggini, E, Crosslin, DR, S. Bevan (7626584), Parsa, A., Franco, Oscar H., Bown, Matthew J., Lange, LA, Bradfield, J.P. (Jonathan), Bottinger, EP, Smith, A.V., Lubitz, S.A., Qu, LM, Erdmann, J. (Jeanette), Angelantonio, E.D. (Emanuele Di), Crossman, D, W. K. Ho (7646081), Franceschini, N., Nalls, M. A., Thompson, S.D. (Susan D.), Wood, Angela M, Nelson, C. P., Keller, M. F., Scott, R.A. (Robert), Mitchell, GF, Langefeld, C.D., Qu, L., Smith, N.L. (Nicholas), Bis, J.C., Samani, N.J., Luo, Yang, Rader, Daniel J., Kathiresan, S, Walston, Jeremy D., Soranzo, N., Butterworth, A.S. (Adam), Crossman, D. (David), Collins, R, Sweeting, M., Porcu, E. (Eleonora), Burgess, S. (Stephen), Watkins, H. (Hugh), Hayward, N.K., Baurecht, H. (Hansjörg), Burgess, S., Markus, HS, Freitag, Daniel F., Iles, M. M., W. Zhang (820655), Rasmussen-Torvik, L.J., Thompson, D. (Deborah), Wood, A.M., Kleber, M.E. (Marcus), Tracy, R.P. (Russell), Bis, Joshua C., Huang, Jie, L. Qu (822458), Collins, R., Farrall, M., Li, Y, Hayward, Nicholas K., Parsa, A, Young, Robin, Easton, D. F., Chubb, D., Kullo, Iftikhar J., B. M. Psaty (7605224), A. S. Hall (7605176), Clarke, R. (Robert), D. Saleheen (7605173), Porcu, Eleonora, Grande, P. (Peer), Zeggini, E. (Eleftheria), Zeng, L, N. Soranzo (7608857), Chambers, J.C., M. Nikpay (7646114), L. J. Rasmussen-Torvik (7646174), J. C. Chambers (7605185), Iles, Mark M., K. Panoutsopoulou (7632989), M. Barbalic (7605845), Mitchell, Gary F., Nordestgaard, BG, Porcu, E, Kaptoge, Stephen, Lange, L.A. (Leslie), Crosslin, David R., Parsa, A. (Afshin), Soranzo, Nicole, Hofman, A. (Albert), Chambers, J.C. (John C.), J. A. Pacheco (7646177), O Reilly, M, Maerz, W, S. Weidinger (7646207), Morgan, G., Whiffin, Nicola, Scott, Robert A, Howson, Joanna M. M., Ganesh, S.K. (Santhi), Ala-Korpela, Mika, Scott, RA, Young, R, Müller-Nurasyid, Martina, Bishop, D.T., Jones, G.T. (Gregory), Crossman, David, H. Kuivaniemi (7646135), Kooner, Jaspal S., Willeit, Peter, de Bakker, Paul I.W., Kooner, JS, Tybjaerg-Hansen, Anne, Wang, Yufei, Nelson, C.P., Nordestgaard, Borge G., S. Baltic (7646198), Thorleifsson, Gudmar, Watkins, Hugh, Harris, T. B., D. S. Carrell (7646171), Thompson, D, F. N. G. van 't Hof (7646123), Malinowski, Jennifer, Walston, J.D., C. Polychronakos (7646231), J. D. Walston (7646291), A. S. Butterworth (7605158), Howson, J.M.M. (Joanna M.M.), Schunkert, Heribert, Saleheen, Danish, van 't Hof, Femke N G, Lange, L.A., Wilkinson, Ian B., Spackman, Sarah, N. J. Wareham (7608962), Baurecht, Hansjörg, Bradfield, Jonathan P., T. Assimes (7646279), Kathiresan, Sekar, Panoutsopoulou, K., Markus, Hugh S., Carrell, DS, Ferreira, M. A., Verma, Shefali S., Ferreira, M.A. (Manuel), Goel, A. (Anuj), M. Sweeting (7646084), van 't Hof, F. N. G., J. Erdmann (7603664), G. Morgan (1390121), Sanna, S. (Serena), Eisen, Timothy, Peissig, P. L., Easton, D.F., Wilkinson, IB, Markus, H.S. (Hugh), Freitag, D., Ramond, A., H. Goldschmidt (5077982), Jones, GT, Morgan, G, G. E. Delgado (7646117), Tromp, G. (Gerard), Luo, Y, Hopewell, J.C., Ligthart, S. (Symen), Panoutsopoulou, Kalliope, McPherson, R., Alam, Dewan S., Thompson, SD, Timpson, N.J., A. Ramond (7646093), Thompson, SG, R. Do (7605920), D. F. Freitag (7605161), Thompson, Simon G., Ritchie, M. D., Rasmussen-Torvik, Laura J., Samani, NJ, Danesh, J, E. Porcu (3354512), I. J. Kullo (7646153), Chowdhury, R., Zeng, L. (Lingyao), Wilkinson, I. B., Goldschmidt, H. (Hartmut), Kathiresan, S., Bottinger, E.P. (Erwin), I. B. Wilkinson (7646186), Kettunen, Johannes, A. van Rij (7646129), T. Eisen (7646243), Thompson, S. G., Nikpay, M., Tybjærg-Hansen, Anne, Sanna, S, D. M. Evans (7624460), de Bakker, P.I.W., S. Ligthart (7646120), Bishop, D. Timothy, Nalls, Mike A., Chubb, D, Baltic, Svetlana, Bishop, DT, Goel, A, Assimes, T.L. (Themistocles), Franco Duran, OH, Qu, L, Mitchell, G.F. (Gary), Chubb, D. (Daniel), Alam, D.S. (Dewan S.), M. H. Law (7646267), M. D. Ritchie (7646138), Müller-Nurasyid, M. (Martina), Thorleifsson, G. (Gudmar), S. Sanna (7609256), Walston, J. D., Eisen, T., Polychronakos, Constantin, Muller-Nurasyid, M, Butterworth, Adam S., Crawford, D. C., Zhang, W, Bishop, D.T. (David Timothy), Evans, DM, Butterworth, AS, Bis, JC, Pacheco, J.A., Nordestgaard, Børge G., Zeng, Lingyao, Goel, Anuj, M. Farrall (6522599), Watkins, H., Hayward, N. (Nick), Felix, JF, M. Dunlop (7596542), A. M. Wood (7642988), Howson, J.M.M., K. Hemminki (7646240), Danesh, J., Grande, P., Langefeld, CD, Thompson, S.G., Hemminki, K., Rasmussen-Torvik, LJ, Keller, Margaux F., Singleton, Andrew, ?, ?, Kleber, M, Saleheen, D, Boettinger, EP, Wood, AM, Kettunen, J. (Johannes), Nikpay, M. (Majid), Crawford, D.C. (Dana), G. Thorleifsson (7606022), Zwart, J-A. (John-Anker), Nikpay, M, Felix, Janine, Keller, M.F., Böttinger, E.P., Thompson, S. D., Hakonarson, H., T. B. Harris (7605353), Ritchie, M.D. (Marylyn D.), Soranzo, N. (Nicole), N. Franceschini (7625954), Weidinger, Stephan, Baurecht, Hansjoerg, Peissig, PL, Staley, J. R., R. A. Scott (2840021), Pacheco, J.A. (Jennifer A.), Felix, J. F., Tracy, R., Brown, MA, Di Angelantonio, E, R. S. Houlston (7646258), Wareham, N.J. (Nick), Bakker, P.I.W. (Paul) de, Crawford, D.C., Lubitz, Steven A., Huang, J, Alam, D. S., Franco, OH, Gudnason, V. (Vilmundur), Kullo, I.J., M. Mueller-Nurasyid (7646213), Do, Ron, Kleber, Marcus, Schunkert, H., Reilly, M.P. (Muredach), Tomlinson, Ian P., Reilly, M, Kessler, T. (Thorsten), Franceschini, Nora, Goel, A., McPherson, R. (Ruth), Ritchie, MD, McCarty, C.A., Qu, L. (Liming), J. M. M. Howson (7646075), D. S. Alam (7646294), N. L. Smith (7646216), Al Shafi Majumder, A., Spackman, S., Erdmann, J., Ligthart, Symen, Reilly, M., Chambers, J. C., E. P. Boettinger (7646162), Law, M.H., Nielsen, Sune F, Felix, Janine F., M. Kleber (7609331), Lund University., Butterworth, A.S., Carrell, David S., Willeit, J. (Johann), Scott, R. A., McPherson, R, Nelson, Christopher P., Sudman, M., Henrion, M, Bevan, Steve, Gudnason, V, Staley, J.R., Malinowski, J., Wang, Y. (Yufei), S. Kathiresan (7606013), Dehghan, A., S. Burgess (4176619), Whiffin, N., Wareham, N. J., Bown, M. J., Wareham, NJ, Kessler, T., Sweeting, M. (Michael), Sudman, Marc, Smith, Albert V., Chambers, John C., Bradfield, J. P., Tybjaerg-Hansen, A, J. C. Hopewell (7605365), Felix, J.F. (Janine), L. Zeng (7646108), Lubitz, SA, M. A. Nalls (7646225), Scott, R.A., Markus, H.S., van Rij, Andre, Samani, N.J. (Nilesh), Harris, TB, Freitag, C.M. (Christine), A. Goel (7602413), Kullo, IJ, Franke, A. (Andre), Wareham, Nicholas J., Saleheen, D., Ramond, A, Kathiresan, Sekhar, Jones, Gregory T, Sweeting, Michael, Ligthart, S., Barbalic, Maja, Collins, Rory, Rader, DJ, Timpson, Nicholas J., Smith, A.V. (Davey), Hofman, Albert, Henrion, M., D. R. Crosslin (7646168), G. T. Jones (7627466), Thompson, Deborah, Ganesh, S.K., Wilkinson, I.B., Evans, David M., Tromp, G, Bruijn, L., Nejentsev, S. (Sergey), Kuivaniemi, H., Majumder, Abdullah Al Shafi, Do, R. (Ron), Nordestgaard, B. G., K. Stefansson (7606001), Gorski, M, Al Shafi Majumder, Abdullah, Kettunen, J, Majumder, AAS, M. Ala-Korpela (3442535), Gottesman, O, Assimes, T., McCarty, C. A., Barbalic, M, R. Clarke (7602407), Rasmussen-Torvik, L. J., Walston, JD, Whiffin, N. (Nicola), Tomlinson, IP, Willeit, P, Evans, D.M., Bruijn, Lucie, Nielsen, S.F., Morgan, G. (Gareth), de Bakker, P. I. W., Gudnason, V., Bis, J. C., Tracy, R, Baurecht, H, Polychronakos, C., Nielsen, S.F. (Sune), Bruijn, L. (Lucie), Böttinger, E. P., Bevan, S. (Steve), Kullo, I. J., De Bakker, PIW, McCarty, CA, Mitchell, G. F., Bishop, D. T., Carrell, D.S., Weidinger, S, Mueller-Nurasyid, Martina, Ala-Korpela, M., Samani, Nilesh J., M. A. Ferreira (7646201), J. Danesh (7605383), Hofman, Bert, Law, M.H. (Matthew H.), Watkins, H, Singleton, A., Huang, J. (Jie), Zhang, W. (Weihua), Mitchell, G.F., Van 't Hof, FNG, Nielsen, Sune F., Thompson, Susan D., Barbalic, M. (maja), Malinowski, J, Majumder, AA, Willeit, P., Soranzo, N, I. P. Tomlinson (7646237), Di Angelantonio, Emanuele, Dehghan, A, Li, Yunlei; id_orcid, Baas, A.F. (Annette), Easton, DF, Luo, Y., Staley, JR, A. Tybjaerg-Hansen (7605182), Kaptoge, S., Smith, N. L., Baurecht, H., Kleber, M., Hemminki, K, Zeggini, Eleftheria, Hemminki, K. (Kari), Dunlop, M, Sudman, M. (Marc), Kuivaniemi, H, Angelantonio, Emanuele Di, A. Dehghan (7626011), Brown, M.A. (Matthew), Ho, Weang Kee, Keller, M.F. (Margaux), Kaptoge, S, Baas, Annette F., Henrion, M. (Marc), Kessler, T, Rij, A.M. (Andre) van, Staley, J.R. (James R.), Peissig, P.L. (Peggy L.), Harris, T.B., Chowdhury, Rajiv, M. Henrion (7646249), Clarke, Robert, Chambers, JC, Ramond, Anna, Andrade, M. (Mariza) de, Baltic, S, Boettinger, Erwin P., Alam, D.S., L. Bruijn (7646195), Nejentsev, Sergey, Baltic, S. (Svetlana), Clarke, R., Thorsteinsdottir, Unnur, Kuivaniemi, H. (Helena), Chowdhury, R. (Rajiv), de Andrade, M., Angelantonio, E. D., W. Maerz (7646285), Kullo, I. (Iftikhar), Crossman, D., Hakonarson, H. (Hakon), Wilkinson, I.B. (Ian B.), Tromp, G., Ligthart, S, H. Schunkert (7603670), Tromp, Gerard, S. Kaptoge (7605374), Dunlop, M. (Malcolm), Gorski, M., Böttinger, Erwin P., Pacheco, JA, Harris, Tamara B., P. I. W. de Bakker (7605305), Timpson, N. J., Crosslin, D.R. (David), Bradfield, J.P., Thorleifsson, G, Timpson, NJ, Law, Matthew H., Nordestgaard, B.G. (Børge), Gudnason, Vilmundur, Bradfield, JP, H. Hakonarson (7609127), N. K. Hayward (7646270), Goldschmidt, H., Singleon, Andrew, P. Grande (7646102), Farrall, Martin, Wood, A. M., V. Gudnason (7605347), Crawford, Dana C., Do, R, Verma, S.S., Houlston, RS, Morgan, Gareth, Singleton, A. (Andrew), J. F. Felix (7625948), R. Collins (7159586), Zeng, LY, Clarke, R, Thompson, S.D., A. Franke (7412741), Dehghan, A. (Abbas), Van Rij, A, Smith, A. V., Rader, D.J., Panoutsopoulou, K, Tybjærg-Hansen, A., Bruijn, L, Nalls, MA, Kastrati, Adnan, S. K. Ganesh (7626842), Angelantonio, E.D., Baltic, S., R. Tracy (7646282), Danesh, John, A. Kastrati (7646288), Thorsteinsdottir, U., Easton, D.F. (Douglas), Harshfield, E. (Eric), Kastrati, A. (Adnan), Verma, SS, Zeng, L., März, W., Howson, JMM, Thorleifsson, G., Iles, M.M. (Mark M.), R. McPherson (7605974), Spackman, S. (Sarah), Do, R., Rader, D. J., D. J. Rader (7605215), R. Chowdhury (7646300), Danesh, J. (John), R. Young (7646078), P. L. Peissig (7646156), Brown, Matthew A., Psaty, BM, Verma, S.S. (Shefali S.), Zeggini, E., Schunkert, H. (Heribert), Thompson, S.G. (Simon), McPherson, Ruth, Chowdhury, R, J. Huang (2342368), Jones, Gregory T., Smith, NL, Psaty, B.M., Assimes, Themistocles, Zhang, Weihua, O. H. Franco (7625993), Brown, M.A., Hofman, A, A. Hofman (4269889), Hopewell, Jemma C, H. Watkins (7602419), Kastrati, A., Hall, A.S., Wood, A.M. (Angela), Ala-Korpela, M, C. D. Langefeld (7646192), Ho, W. K., Ganesh, S. K., Lubitz, S. A., Hopewell, JC, Nejentsev, S, Y. Luo (1398985), Maerz, Winfried, Baas, AF, C. A. McCarty (7646159), N. Whiffin (7646252), Hopewell, J., Houlston, R. (Richard), Timpson, N.J. (Nicholas), Allan, J.M. (James), Alam, DS, Kaptoge, S. (Stephen), Delgado, Graciela E, Ho, W.K. (Weang Kee), Sudman, M, Thorsteindottir, Unnur, Kettunen, J., Langefeld, C. D., Tomlinson, I. P., Ganesh, SK, Stefansson, Kari +874 morecore +5 more sourcesTargeting Amastigote and Trypomastigote Phases: Multi‐Epitope Vaccine Strategy Against Trypanosoma cruzi
Biotechnology and Applied Biochemistry, EarlyView.ABSTRACT
Effective vaccines against Trypanosoma cruzi, the causative agent of Chagas disease, are urgently needed. Here, we report the design and in silico validation of a novel multiepitope vaccine construct targeting the key surface proteins ASP‐2 and gp82. Using a comprehensive immunoinformatics pipeline, we identified and selected 38 potent T‐cell (Maria Karolaynne da Silva, Caio Patrício de Souza Sena, Davi Serradella Vieira, Magdi E. A. Zaki, Leow Chiuan Yee, Shahina Akter, Umberto Laino Fulco, Jonas Ivan Nobre Oliveira, João Firmino Rodrigues‐Neto +8 morewiley +1 more sourceGJD Modulates Cardiac/Vascular Inflammation and Decreases Blood Pressure in Hypertensive Rats
Mediators of Inflammation, 2022 Gedan Jiangya decoction (GJD) (aqueous ethanol extract), a traditional Chinese medicine formula which contain six botanical drugs (Uncaria rhynchophylla (Miq.) Miq., Salvia miltiorrhiza Bunge, Pueraria lobata (Willd.) Ohwi, Eucommia ulmoides Oliv ...Shadi A. D. Mohammed, Hanxing Liu, Salem Baldi, Pingping Chen, Fang Lu, Shumin Liu +5 moredoaj +1 more sourceRecent Advances in Exosome‐Based Nanodelivery Systems for Traumatic Brain Injury Treatment
Med Research, EarlyView.An overview of functional modification, therapeutic effects, molecular composition, and delivery strategies for exosomes. ABSTRACT
Traumatic brain injury (TBI) is a highly heterogeneous neurological condition with extremely high rates of mortality and disability.Jue Zhu, Weiquan Liao, Ziqi Lian, Mengdan Zhang, Chenxing Wang, Xingjia Zhu, Lin Zhang, Jian Chen, Zhichao Lu, Peipei Gong +9 morewiley +1 more sourceThe progression and topographic distribution of interleukin-1beta expression after permanent middle cerebral artery occlusion in the rat.
, 1999 The cytokine interleukin-1 (IL-1) has been implicated in the exacerbation of ischemic damage in the brains of rodents. This study has ascertained the cellular localization and chronologic and topographic distribution of pro/mature interleukin-1beta (IL ...Toulmond, S, Hunt, J, Stroemer, R, Davies, CA, Rothwell, NJ., Loddick, S +5 morecore +8 more sourcesImmunomodulatory Properties of Withania somnifera: Regulation of Innate Immune Cells and Clinical Implications
Phytotherapy Research, EarlyView.ABSTRACT
Withania somnifera (L.) Dunal (WS), commonly known as Ashwagandha, is a prominent medicinal herb in Ayurveda, with extensive therapeutic potential attributed to its diverse phytochemical profile. This review critically examines the immunomodulatory properties of WS, focusing on innate immune cell populations, including neutrophils, eosinophils,Rana Yukta, Sonalika Gupta, Gagandeep Kaur, Partha Sarathi Mondal, Milirani Das, Anagha Ranade, Alok Kumar Srivastava, Sachin Kumar, Manoj Kumar Barthwal, Madhu Dikshit +9 morewiley +1 more source
