Intracellular Chloride Concentration Changes Modulate IL-1β Expression and Secretion in Human Bronchial Epithelial Cultured Cells [PDF]
Cystic fibrosis (CF) is caused by mutations in the CFTR gene, which encodes a cAMP‐regulated chloride channel. Several cellular functions are altered in CF cells. However, it is not clear how the CFTR failure induces those alterations.
Clauzure, Mariangeles +6 more
core +1 more source
OBJECTIVE: To analyze the usefulness of determining the cerebrospinal fluid(CSF) levels of tumor necrosis factor-alpha(TNF-alpha),interleukin-1beta(IL-1beta) and interleukin-6(IL-6)for the early diagnosis and evaluation of the prognosis of neonatal ...
Vera Lúcia Jornada Krebs +3 more
doaj +1 more source
The Chemokine CCL2 Mediates the Seizure-enhancing Effects of Systemic Inflammation [PDF]
Epilepsy is a chronic disorder characterized by spontaneous recurrent seizures. Brain inflammation is increasingly recognized as a critical factor for seizure precipitation, but the molecular mediators of such proconvulsant effects are only partly ...
Allegra, M +8 more
core +2 more sources
Production of interleukin 1beta by human hematopoietic progenitor cells. [PDF]
The production of interleukin 1beta (IL-1beta) by human hematopoietic stem/progenitor cells was studied to explore the concept that these cells are not merely responders to stimuli from their microenvironment, but can themselves produce a powerful biomodulator.
K, Watari +5 more
openaire +2 more sources
Relationship between IL-1β production and endodontic status of human periapical lesions [PDF]
Background/Aim. Apical periodontitis is mainly caused by bacterial infection within the root canal and periapical bone destruction which are prominent features of this lesion.
Popovska Lidija +6 more
doaj +1 more source
Colchicine therapy in acute coronary syndrome patients acts on caspase-1 to suppress NLRP3 inflammasome monocyte activation [PDF]
Inflammasome activation, with subsequent release of pro-inflammatory cytokines interleukin-1β (IL-1β) and IL-18, has recently been implicated in atherosclerosis-associated inflammation. This study aims to assess in acute coronary syndrome (ACS) patients (
Christina Bursill +8 more
core +1 more source
Lack of Interleukin 1-beta Expression Following Orthodontic Induced Root Resorption [PDF]
Objective: To determine the effect of orthodontic tooth movement on the expression ofinterleukin-1β mRNA in rats using RT-PCR.Materials and Methods: Sample consisted of eighteen 8-week-old male Wistar rats.
Massoud Seifi +4 more
doaj
Several case-control studies have been performed in different populations to uncover the association between interleukin-1 beta gene, interleukin-1 receptor antagonist gene polymorphisms and urolithiasis.
Jiaxuan Qin, Jinchun Xing, Zonglong Cai
doaj +1 more source
Tendinopathy—from basic science to treatment [PDF]
Chronic tendon pathology (tendinopathy), although common, is difficult to treat. Tendons possess a highly organized fibrillar matrix, consisting of type I collagen and various 'minor' collagens, proteoglycans and glycoproteins.
A McCormick +69 more
core +1 more source
Dibutyltin‐induced alterations of interleukin 1beta secretion from human immune cells [PDF]
AbstractDibutyltin (DBT) is used to stabilize polyvinyl chloride plastics (including pipes that distribute drinking water) and as a de‐worming agent in poultry. DBT is found in human blood, and DBT exposures alter the secretion of tumor necrosis factor alpha and interferon gamma from lymphocytes.
Shyretha, Brown +2 more
openaire +2 more sources

