Results 31 to 40 of about 23,893 (178)

Arthrogenic human synovial cysts: immunohistochemical profile of interleukin-1beta, interleukin-6, tumour necrosis factor-alpha

Folia Morphologica, 2021
BACKGROUND: Synovial cysts are currently classified as degenerative lesions affecting the joint capsule or adjacent structures. MATERIALS AND METHODS: In our study we describe the results obtained in an immunohistochemical study comprising 18 patients ...
S. Taurone, M. T. Santarelli, C. De Ponte, L. Bardella, M. Ralli, C. Morselli, A. Nicolai, A. Greco, A. Ferretti, M. Artico   +9 more
doaj   +1 more source

Single nucleotide polymorphisms in IL-1A RS1800587, IL-1B RS1143634 and vitamin D receptor rs731236 in stage III grade B/C periodontitis

Balkan Journal of Medical Genetics, 2023
The purpose of the study is to determine the prevalence of interleukin (IL)-1A (rs1800587), IL-1B (rs1143634) and vitamin D receptor (VDR) (TaqI, rs731236) gene polymorphisms in the Turkish population and their association with Stage III Grade B/C ...
Özturk Özener H., Tacal Aslan B., Eken B.F., Agrali Ö.B., Yildrim H.S., Altunok E.Ç., Ulucan K., Kuru L.   +7 more
doaj   +1 more source

Evaluation of interleukin -1B (+3954) gene polymorphism in patients with chronic and aggressive periodontitis: A genetic association study

Contemporary Clinical Dentistry, 2012
Background: IL-1 cytokines have central roles in the pathogenesis of periodontal disease. Polymorphism in the locus +3954 (C/T) of the human IL-1B gene has been shown to affect the levels of this cytokine.
Sujata S Masamatti, Ashish Kumar, Tarun Kumar A Baron, Dhoom S Mehta, Kishore Bhat   +4 more
doaj   +1 more source

Context-Dependent IL-1 mRNA-Destabilization by TTP Prevents Dysregulation of Immune Homeostasis Under Steady State Conditions

Frontiers in Immunology, 2020
The bioavailability of the major pro-inflammatory cytokines IL-1α and IL-1β is tightly controlled by transcription and post-translational processing to prevent hyperinflammation.
Lucy Sneezum, Kevin Eislmayr, Helene Dworak, Vitaly Sedlyarov, Anita Le Heron, Florian Ebner, Irmgard Fischer, Yoichiro Iwakura, Pavel Kovarik   +8 more
doaj   +1 more source

GJD Modulates Cardiac/Vascular Inflammation and Decreases Blood Pressure in Hypertensive Rats

Mediators of Inflammation, 2022
Gedan Jiangya decoction (GJD) (aqueous ethanol extract), a traditional Chinese medicine formula which contain six botanical drugs (Uncaria rhynchophylla (Miq.) Miq., Salvia miltiorrhiza Bunge, Pueraria lobata (Willd.) Ohwi, Eucommia ulmoides Oliv ...
Shadi A. D. Mohammed, Hanxing Liu, Salem Baldi, Pingping Chen, Fang Lu, Shumin Liu   +5 more
doaj   +1 more source

Ambient Light‐Activatable Luminescent Particle‐Embedded Conformal Patch for Photochemical Tissue Bonding and Photobiomodulated Healing

Advanced Materials, EarlyView.
We report a wearable photonic patch integrating room light‐ and sunlight‐activatable luminescent particles (RSLPs) for both photochemical tissue bonding and photobiomodulation. RSLPs harvest ambient light and emit red luminescence to drive chlorin e6–mediated collagen crosslinking.
Kyungjoo Jo, Seong‐Jong Kim, Seung Oh Jung, Kyeongtaek Lee, Mungu Kim, Kwanghyeon Park, Yewon Seo, Boram Park, Dongchul Jo, Jongshin Kim, Jin Huh, Hyemin Kim, Sei Kwang Hahn   +12 more
wiley   +1 more source

Zeolite abrogates cadmium-induced testicular damage in rats: implication of NF-κB/ TNF-α/IL-1β Pathway [PDF]

Arquivo Brasileiro de Medicina Veterinária e Zootecnia
Cadmium (Cd) is an environmental pollutant affecting various tissues and organs, including the testis. Many studies demonstrated that Cd toxicity causes testicular impairment through oxidative stress and inflammatory action.
N.M. Ibrahim, A.M. Kandil, R.S. Ali, R. Hesham, S. El-Ashram, M.I. Alquraishi, R. Abdel-Gaber, M.A. Dkhil, A.A. Elhemiely   +8 more
doaj   +1 more source

Production of interleukin 1beta by human hematopoietic progenitor cells. [PDF]

Journal of Clinical Investigation, 1996
The production of interleukin 1beta (IL-1beta) by human hematopoietic stem/progenitor cells was studied to explore the concept that these cells are not merely responders to stimuli from their microenvironment, but can themselves produce a powerful biomodulator.
K, Watari, H, Mayani, F, Lee, W, Dragowska, P M, Lansdorp, J W, Schrader   +5 more
openaire   +2 more sources

Membrane‐Active Peptide Protects Against Inflammation by Targeting NLRP3 Activation at the Trans‐Golgi Network

Advanced Science, EarlyView.
The membrane‐active peptide Pep19‐2.5 reduces harmful inflammation by blocking activation of the NLRP3 inflammasome at trans‐Golgi network membranes. By targeting key membrane interactions, Pep19‐2.5 suppresses inflammatory IL‐1β production and alleviates allergic airway inflammation in mice, leading to reduced immune cell infiltration and improved ...
Jonas Engelhardt, Nico Kirsch, Aileen Kerfin, Lars P. Lunding, Dominic Ferber, Hannes Buthmann, Ilka Schreier, Carlotta Bosio, Ann‐Kathrin Dobbelstein, Anna Klawonn, Rebecca C. Coll, Lena Bauernhofer, Sandro Keller, Matthias Geyer, Michael Wegmann, Andra B. Schromm, Günther Weindl   +16 more
wiley   +1 more source

Targeting Amastigote and Trypomastigote Phases: Multi‐Epitope Vaccine Strategy Against Trypanosoma cruzi

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Effective vaccines against Trypanosoma cruzi, the causative agent of Chagas disease, are urgently needed. Here, we report the design and in silico validation of a novel multiepitope vaccine construct targeting the key surface proteins ASP‐2 and gp82. Using a comprehensive immunoinformatics pipeline, we identified and selected 38 potent T‐cell (
Maria Karolaynne da Silva, Caio Patrício de Souza Sena, Davi Serradella Vieira, Magdi E. A. Zaki, Leow Chiuan Yee, Shahina Akter, Umberto Laino Fulco, Jonas Ivan Nobre Oliveira, João Firmino Rodrigues‐Neto   +8 more
wiley   +1 more source