Results 11 to 20 of about 44,626 (220)

Contribution of interleukin-1beta in neuropathic pain

Chinese Journal of Contemporary Neurology and Neurosurgery, 2013
Interleukin-1beta (IL-1β), a pro-inflammatory cytokine, has been implicated in the development of peripheral and central sensitization that is charactistic of neuropathic pain. Recent studies demonstrated that IL-1β is an important messenger that is interacted with glia and neurons in the central neurous system in the neuropathic pain states.
Wei GUO
openaire   +2 more sources

IL-1beta promotes the age-associated decline of beta cell function

iScience, 2021
Summary: Aging is the prime risk factor for the development of type 2 diabetes. We investigated the role of the interleukin-1 (IL-1) system on insulin secretion in aged mice.
Marianne Böni-Schnetzler, Hélène Méreau, Leila Rachid, Sophia J. Wiedemann, Friederike Schulze, Kelly Trimigliozzi, Daniel T. Meier, Marc Y. Donath   +7 more
doaj   +1 more source

Total Triterpenes of Wolfiporia cocos (Schwein.) Ryvarden & Gilb Exerts Antidepressant-Like Effects in a Chronic Unpredictable Mild Stress Rat Model and Regulates the Levels of Neurotransmitters, HPA Axis and NLRP3 Pathway

Frontiers in Pharmacology, 2022
Purpose:Wolfiporia cocos is frequently used in traditional Chinese medicine to treat depression. However, antidepressant-like effects of the main active ingredients of Wolfiporia cocos, total triterpenes of Wolfiporia cocos (TTWC), are not well studied ...
Xiang Pan, Kezhuo Chen, Sijie Han, Xinyao Luo, Dandan Zhang, Hanrui Zhang, Lian Zhang, Xuxiang Zhou, Jing Li, Jingxian Fang, Shiqin Wang, Xiaochuan Ye   +11 more
doaj   +1 more source

Interleukin 1-beta analysis in chronically inflamed and healthy human dental pulp [PDF]

Vojnosanitetski Pregled, 2017
Background/Aim. Proinflammatory cytokines can act like endogenous pyrogen interleukin 1 (IL-1), interleukin 6 (IL-6) and tumour necrosis factor alpha (TNF α) which regulate the synthesis of secondary mediators and other proinflammatory cytokines through ...
Šubarić Ljiljana, Mitić Aleksandar, Matvijenko Vladimir, Jovanović Radovan, Živković Dušan, Perić Dejan, Vlahović Zoran   +6 more
doaj   +1 more source

Impaired interleukin-1beta and c-Fos expression in the hippocampus is associated with a spatial memory deficit in P2X(7) receptor-deficient mice. [PDF]

PLoS ONE, 2009
Recent evidence suggests that interleukin-1beta (IL-1beta), which was originally identified as a proinflammatory cytokine, is also required in the brain for memory processes.
Virginie F Labrousse, Laurence Costes, Agnès Aubert, Muriel Darnaudéry, Guillaume Ferreira, Thierry Amédée, Sophie Layé   +6 more
doaj   +1 more source

GINGIVAL TISSUE IL-1beta AND PGE2 LEVELS IN PATIENTS WITH CHRONIC PERIODONTITIS AFTER ADDITIONAL THERAPY WITH NON-STEROIDAL ANTI-INFLAMMATORY DRUGS [PDF]

Journal of IMAB, 2010
Background: The understanding of the pathogenesis of periodontitis makes various progresses in the last decades. Today it is well known that the synthesis of high levels of pro-inflammatory mediators from gingival tissues in response to ...
Christina Popova, Antoaneta Mlachkova
doaj   +1 more source

Effects of N-acetylcysteine on the inflammatory response and bacterial translocation in a model of intestinal obstruction and ischemia in rats

Acta Cirúrgica Brasileira, 2023
Purpose: To evaluate effect of N-acetylcysteine (NAC) associated with Ringer lactate or hypertonic saline in inflammation and bacterial translocation on experimental intestinal obstruction (IO). Methods: Wistar rats was subjected to IO.
Rafael Izar Domingues da Costa, Joao Marcos da Silva Fischer, Roberto Rasslan, Marcia Kiyomi Koike, Edvaldo Massazo Utiyama, Edna Frasson de Souza Montero   +5 more
doaj   +1 more source

Malarial hemozoin activates the NLRP3 inflammasome through Lyn and Syk kinases. [PDF]

PLoS Pathogens, 2009
The intraerythrocytic parasite Plasmodium -- the causative agent of malaria -- produces an inorganic crystal called hemozoin (Hz) during the heme detoxification process, which is released into the circulation during erythrocyte lysis.
Marina Tiemi Shio, Stephanie C Eisenbarth, Myriam Savaria, Adrien F Vinet, Marie-Josée Bellemare, Kenneth W Harder, Fayyaz S Sutterwala, D Scott Bohle, Albert Descoteaux, Richard A Flavell, Martin Olivier   +10 more
doaj   +1 more source

Interleukin 1-beta (Il-1β) polymorphism and orthodontics: a systematic review

Revista Facultad de Odontología Universidad de Antioquia, 2019
Introduction: the aim of this systematic review is to explore the published literature to analyze the relationship between polymorphism of interleukin 1-beta (IL-1β) and orthodontics.
Juan Fernando Aristizábal, Héctor Ríos, Diego Rey, María Antonia Álvarez, Beatriz Parra-Patiño, Mario Ortiz   +5 more
doaj   +1 more source

The Association Between Shift Work and Immunological Biomarkers in Nurses

Frontiers in Public Health, 2020
Objectives: Shift work is associated with several negative health effects. The underlying pathophysiological mechanisms are unclear, but low-grade inflammation has been suggested to play a role.
Bjørn Bjorvatn, Bjørn Bjorvatn, John Axelsson, John Axelsson, Ståle Pallesen, Ståle Pallesen, Siri Waage, Siri Waage, Øystein Vedaa, Øystein Vedaa, Kjersti M. Blytt, Kjersti M. Blytt, Hogne V. Buchvold, Bente E. Moen, Eirunn Thun   +14 more
doaj   +1 more source