Results 251 to 260 of about 22,453,438 (395)
This study investigates the metabolic vulnerabilities of glioblastoma (GBM), an aggressive brain tumor. Research demonstrates that iron chelation therapy, in combination with standard chemotherapy, significantly enhances the efficacy of treatment against resistant GBM cells in a 3D tumoroid model.
Meitham Amereh+8 more
wiley +1 more source
Interleukin-2 receptor signaling acts as a checkpoint that influences the distribution of regulatory T cell subsets. [PDF]
Shouse AN, Villarino AV, Malek TR.
europepmc +1 more source
Thy-1+ epidermal cells proliferate in response to concanavalin A and interleukin 2. [PDF]
J L Nixon-Fulton+2 more
openalex +1 more source
This work proposes a novel strategy targeting gut microbiota for managing polycystic ovary syndrome (PCOS). Inulin, a gut microbiota modulator, notably boosts the growth of short‐chain fatty acids (SCFAs)‐producers, represented by Bifidobacterium, thereby improving glucolipid metabolism and ovarian function of PCOS through suppressing the inflammatory ...
Lulu Geng+8 more
wiley +1 more source
Interleukin-2-induced skin inflammation. [PDF]
Sommer C+7 more
europepmc +1 more source
As a plant‐derived flavonoid, apigenin directly targets PRDX6 to inhibit its PLA2 activity, blocking HSPA8 activation and disturbing its interactions with ATM and p38MAPK in senescent cells. By dampening wide spectrum expression of the SASP, apigenin prevents loss of tissue homeostasis, improves organ function, and alleviates multiple age‐related ...
Hongwei Zhang+10 more
wiley +1 more source