Dual Foreign Body Response Mitigation Strategies for Implantable Glucose Sensors
The foreign body response negatively impacts the analytical lifetime of implantable glucose sensors due to a heightened immune response and deposition of collagen. While nitric oxide release has shown promise as a foreign body response mitigation strategy, improvement is limited by the duration of release.
Taron M. Bradshaw+9 more
wiley +1 more source
Zinc Deficiency Exacerbates Lead-Induced Interleukin-2 Suppression by Regulating CREM Expression. [PDF]
Trojan HE, Rink L, Jakobs J.
europepmc +1 more source
Toxicity and therapeutic efficacy of high-dose interleukin 2. In vivo infusion of antibody to NK-1.1 attenuates toxicity without compromising efficacy against murine leukemia. [PDF]
David Peace, Martin A. Cheever
openalex +1 more source
Compact Multichannel Plasmonic Device for Rapid and Versatile Inflammatory Biomarker Analysis
A multichannel plasmonic biosensor has been developed for the simultaneous detection of up to four inflammatory biomarkers relevant to sepsis diagnostics. Its performance has been optimized, and analytical validation has been conducted for the detection in diluted serum, highlighting its potential for clinical applications.
Juliana Fátima Giarola+3 more
wiley +1 more source
Low-dose interleukin-2 induces clonal expansion of BACH2-repressed effector regulatory T cells following acute coronary syndrome. [PDF]
Case AG+13 more
europepmc +1 more source
Cytokine Engineering Approaches for Regenerative Medicine
Engineered cytokines represent a powerful strategy to promote tissue repair and regeneration by precisely modulating immune responses. This review highlights recent advances in cytokine engineering, including strategies to enhance half‐life, improve tissue and cell targeting, and control receptor signaling.
Shiyi Li, Wenhao You, Mikaël M. Martino
wiley +1 more source
Evaluating Interleukin-2 and Its Receptors As Indicators of Acute Renal Graft Rejection. [PDF]
Gompou A+7 more
europepmc +1 more source
Loss of NR2F6 Protects from Salmonella Typhimurium Infection
Loss of nuclear receptor NR2F6 reduces tissue‐resident macrophage populations. Nr2f6‐deficient mice are protected from weight loss and bacterial load during infection with Salmonella Typhimurium. Pro‐inflammatory cytokines and iron levels are altered in infected Nr2f6‐deficient mice.
Johannes Woelk+8 more
wiley +1 more source