Results 321 to 330 of about 22,658,854 (391)

Tumor-Localized Interleukin-2 and Interleukin-12 Combine with Radiation Therapy to Safely Potentiate Regression of Advanced Malignant Melanoma in Pet Dogs. [PDF]

open access: yesClin Cancer Res
Stinson JA   +10 more
europepmc   +1 more source

Synaptic synergy of T cell receptor and interleukin 2 receptor in CD8+T cells

open access: yes
Capera J   +7 more
europepmc   +1 more source

Interleukin-2–based therapies in cancer

Science Translational Medicine, 2022
Molecular insights into the mechanism of beneficial and adverse effects of interleukin-2 (IL-2) have resulted in the development of improved IL-2 formulations with IL-2 receptor bias and tissue-targeting properties.
M. E. Raeber, Dilara Şahin, O. Boyman
semanticscholar   +1 more source

The Interleukin -2

Acta Clinica Belgica, 1987
SummaryDiscovered in 1976, the lymphokine interleukin-2, intensively studied during the last years, plays a major role in the regulation of the immune function. The authors reviewing its principal properties, anticipate forthcoming prospects of considerable implications in therapy.Acta Clin. Bclg. 42, 4: 255–68.
M. Hiden, P. Neve
openaire   +3 more sources

Interleukin-2 toxicity. [PDF]

open access: possibleJournal of Clinical Oncology, 1991
Because of the ability of interleukin-2 (IL-2) to support the proliferation and activation of numerous types of immunocompetent cells and to support the survival of adoptively transferred lymphocytes, there has been considerable interest in its use in the immunotherapy of malignancies.
Jay P. Siegel, Roj K. Puri
openaire   +2 more sources

A progress report on the treatment of 157 patients with advanced cancer using lymphokine-activated killer cells and interleukin-2 or high-dose interleukin-2 alone.

New England Journal of Medicine, 1987
We studied the effects of adoptive immunotherapy with lymphokine-activated killer (LAK) cells plus interleukin-2 or therapy with high-dose interleukin-2 alone in 157 patients with metastatic cancer for whom standard therapy had proved ineffective or no ...
S. Rosenberg   +12 more
semanticscholar   +1 more source

Regulation of Interleukin 2 Receptor Expression by Interleukin 2

Scandinavian Journal of Immunology, 1986
The regulatory influence of Interleukin 2 (IL‐2) on the expression of IL‐2 receptors (IL.‐2R) was studied using long‐term cultured T‐cell lines and recombinant IL‐2 (r‐IL‐2). Three T‐cell lines with different growth requirements were used as model systems: insulin‐specific BK‐BI‐1.2 cells express IL‐2R transiently after antigenic restimulation ...
T. Diamantstein   +3 more
openaire   +3 more sources

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