Results 361 to 370 of about 22,453,438 (395)
Some of the next articles are maybe not open access.
Journal of the American Medical Association (JAMA), 1994
OBJECTIVE To determine the efficacy of treatment using high-dose bolus interleukin 2 (IL-2) in patients with metastatic melanoma or renal cell cancer.
S. Rosenberg +8 more
semanticscholar +1 more source
OBJECTIVE To determine the efficacy of treatment using high-dose bolus interleukin 2 (IL-2) in patients with metastatic melanoma or renal cell cancer.
S. Rosenberg +8 more
semanticscholar +1 more source
Interleukin-2, Autotolerance, and Autoimmunity
1991Insomma se il modello non riesce a trasformare la realta, la realta dovrebbe riuscire a trasformare il modello…. Se le cose stanno cosi, il modello dei modelli dovra servire a ottenere dei modelli trasparenti, diafani, sottili como ragnatele; magari addiritura a dissolvere i modelli, anzi a dissolversi.
José Luis Andreu +4 more
openaire +3 more sources
Journal of the National Cancer Institute, 1994
BACKGROUND Studies of human tumor-infiltrating lymphocytes (TILs) derived from patients with a variety of histologic types of cancer have demonstrated that cellular immune reactions against established malignancy exist in humans.
S. Rosenberg +9 more
semanticscholar +1 more source
BACKGROUND Studies of human tumor-infiltrating lymphocytes (TILs) derived from patients with a variety of histologic types of cancer have demonstrated that cellular immune reactions against established malignancy exist in humans.
S. Rosenberg +9 more
semanticscholar +1 more source
Clinical applications of interleukin-2
Progress in Growth Factor Research, 1992Interleukin-2 (IL-2) is a cytokine with potent immunomodulating properties which has shown considerable antitumour activity in preclinical models. In clinical trials, the effects of IL-2 given by various routes and schedules have been investigated.
A. von Rohr, Nick Thatcher
openaire +3 more sources
Deregulated T cell activation and autoimmunity in mice lacking interleukin-2 receptor beta.
Science, 1995In mice lacking the interleukin-2 receptor beta chain (IL-2R beta), T cells were shown to be spontaneously activated, resulting in exhaustive differentiation of B cells into plasma cells and the appearance of high serum concentrations of immunoglobulins ...
H. Suzuki +9 more
semanticscholar +1 more source
1985
Publisher Summary This chapter describes certain approaches, which are most useful in the purification and characterization of human IL-2 and which have general applicability throughout the lymphokine field. Interleukin 2 (IL-2, T cell growth factor) is situated at the center of the cascade of antigen-nonspecific factors released during an immune ...
openaire +3 more sources
Publisher Summary This chapter describes certain approaches, which are most useful in the purification and characterization of human IL-2 and which have general applicability throughout the lymphokine field. Interleukin 2 (IL-2, T cell growth factor) is situated at the center of the cascade of antigen-nonspecific factors released during an immune ...
openaire +3 more sources
Immunotherapy with Interleukin-2 [PDF]
, 1989 Chemotherapy is capable of producing durable responses in only a few types of advanced cancer and there is therefore an urgent need for alternative approaches to treatment. For decades, immunologists have held the hope that it might be possible to induce or augment a host antitumour response and produce immune-mediated disease regression.
openaire +1 more source
The role of interleukin-2 during homeostasis and activation of the immune system
Nature reviews. Immunology, 2012O. Boyman, J. Sprent
semanticscholar +1 more source