Results 151 to 160 of about 3,093,388 (334)
Levels of Interleukin‐21 in Patients With Untreated Chronic Periodontitis
Journal of Periodontology, 2011 Background: A growing body of evidence suggested that interleukin (IL)‐21 enhances the effector phase during T‐cell responses. The aim of our study is to determine the levels of IL‐21 in periodontal sites from patients with chronic periodontitis and controls.Methods: The population studied consisted of 34 patients (15 with chronic periodontitis and 19 ...
Dutzan Muñoz, Nicolás +11 more
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Advanced Functional Materials, EarlyView.A multifunctional hydroxyapatite (HAp) coating integrated with silver‐gallium liquid metal nanoparticles (HAp‐Ag‐GaNPs) exhibits dual antibacterial and osteogenic properties. It effectively inhibits Gram‐positive and Gram‐negative bacteria, including resistant strains, while enhancing bone regeneration.
Ngoc Huu Nguyen +17 more
wiley +1 more source
Interleukin 21 Is a T Helper (Th) Cell 2 Cytokine that Specifically Inhibits the Differentiation of Naive Th Cells into Interferon γ–producing Th1 Cells [PDF]
, 2002 Andrea L. Wurster +6 more
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Advanced Functional Materials, EarlyView.This review highlights recent advances in engineering artificial antigen‐presenting cells (aAPCs) as alternatives to dendritic cells for T cell expansion. Key design principles inspired by the immunological synapse are discussed, with emphasis on strategies for polyclonal and antigen‐specific T cell expansion.
Nguyen Thi Nguyen, Yu Seok Youn
wiley +1 more source
Interleukin-21 inhibits dendritic cell activation and maturation [PDF]
, 2003 Katja Brandt +3 more
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Advanced Functional Materials, EarlyView.The temporary transition of macrophages from a pro‐inflammatory phenotype of macrophages (M1) to an anti‐inflammatory phenotype of macrophages (M2) is crucial for tissue repair and regeneration processes. Bacterial outer membrane vesicles (OMVs) are utilized as a “trojan horse” for specific M1 macrophage‐targeting and anti‐inflammatory drug delivery ...
Donglin Cai +9 more
wiley +1 more source
Interleukin-21: Basic Biology and Implications for Cancer and Autoimmunity
Annual Review of Immunology, 2008 Interleukin-21 (IL-21), a potent immunomodulatory four-α-helical-bundle type I cytokine, is produced by NKT and CD4+ T cells and has pleiotropic effects on both innate and adaptive immune responses. These actions include positive effects such as enhanced proliferation of lymphoid cells, increased cytotoxicity of CD8+ T cells and natural killer (NK ...
Spolski, Rosanne, Leonard, Warren J.
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Advanced Functional Materials, EarlyView.A hydrogel for intra‐articular injection for the treatment of rheumatoid arthritis (RA) is formulated and comprehensively studied. After administration, the hydrogel induces a metabolic reprogramming of immunometabolism of macrophages to trigger fatty acid oxidation subsequently inducing polarization of anti‐inflammatory M2 macrophages. This results in
Yutong Song +8 more
wiley +1 more source
Interleukin‐21 Induces T‐cell Activation and Proinflammatory Cytokine Secretion in Rheumatoid Arthritis [PDF]
, 2006 J. Li, Weigan Shen, K.M. Kong, Zhan Liu
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