Results 231 to 240 of about 527,379 (343)

Level of inflammatory cytokines tumour necrosis factor , interleukins 12, 23 and 17 in patients with psoriasis in the context of metabolic syndrome [PDF]

open access: gold, 2018
Magdalena Pirowska   +7 more
openalex   +1 more source

Bimetallic Peroxide Nanocomposites‐Driven Redox Dyshomeostasis to Activate Sequential Cuproptosis and Pyroptosis for Amplified Tumor Immunotherapy

open access: yesAdvanced Science, EarlyView.
Hyaluronic acid‐modified bimetallic peroxide nanocomposites (MgO2‐CuO2@HA) are designed for synergistic tumor therapy. The nanocomposites release Mg2+, H2O2, and Cu2+ in tumor cells, induce cuproptosis via Cu+‐mediated protein aggregation, and activate pyroptosis through caspase‐1/gasdermin D pathways for inducing immunogenic cell death, collectively ...
Guanting He   +8 more
wiley   +1 more source

Interleukin 12/23 and interleukin 23 inhibitors for moderate-to-severe ulcerative colitis: a systematic review and network meta-analysis. [PDF]

open access: yesAnn Gastroenterol
Sawaf B   +14 more
europepmc   +1 more source

Interleukin-23 Mediates Osteoclastogenesis in Collagen-Induced Arthritis by Modulating MicroRNA-223. [PDF]

open access: yesInt J Mol Sci, 2022
Chen SY   +8 more
europepmc   +1 more source

The role of the interleukin‐23/Th17 pathway in cardiometabolic comorbidity associated with psoriasis

open access: hybrid, 2020
Alexander Egeberg   +4 more
openalex   +1 more source

Cleavage‐Resistant CYLD Protects Against Autoimmune Hepatitis

open access: yesAdvanced Science, EarlyView.
Proteolytic cleavage of the deubiquitinase CYLD emerges as a critical driver of autoimmune hepatitis. TNFα‐induced CYLD loss in macrophages amplifies S100A9‐triggered MAPK activation, leading to excessive chemokine production and hepatic inflammation. Pharmacological inhibition of MEK signaling effectively attenuates experimental disease, highlighting ...
Han Liu   +13 more
wiley   +1 more source

Interleukin‐23 Secreted by Activated Macrophages Drives γδT Cell Production of Interleukin‐17 to Aggravate Secondary Injury After Intracerebral Hemorrhage

open access: gold, 2016
Qi Zhong   +16 more
openalex   +1 more source

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