Results 211 to 220 of about 2,862,477 (306)

A Genome-Wide Association Study Identifying Novel Genetic Markers of Response to Treatment with Interleukin-23 Inhibitors in Psoriasis. [PDF]

Genes (Basel)
Zachari S, Liadaki K, Planaki A, Zafiriou E, Kouvarou O, Gerogianni K, Giannoulis T, Mamuris Z, Bogdanos DP, Moschonas NK, Sarafidou T.   +10 more
europepmc   +1 more source

Interleukin-17 vs. Interleukin-23 Inhibitors in Pustular and Erythrodermic Psoriasis: A Retrospective, Multicentre Cohort Study. [PDF]

J Clin Med, 2023
Avallone G, Maronese CA, Murgia G, Carrera CG, Mastorino L, Roccuzzo G, Dapavo P, Alberti-Violetti S, Quaglino P, Ribero S, Marzano AV.   +10 more
europepmc   +1 more source

Spontaneous Non‐Catalyzed Molecular Reactions and Interactions in the Human Body: Biomedical Implications

Advanced Science, EarlyView.
ABSTRACT The human body functions as a natural reactor for a vast network of chemical and biological reactions and physical interactions among small molecules, proteins, cells, and numerous other components. These reactions/interactions are essential for maintaining normal physiological functions.
Yuhao Cai, Chao Zhao
wiley   +1 more source

Disseminated tuberculosis associated with deficient interleukin-23/tyrosine kinase 2 signalling. [PDF]

BMJ Case Rep, 2022
Ojuawo O, Allen R, Hagan G, Piracha S.
europepmc   +1 more source

Bioorthogonal Fluorogenic Reporters for Noninvasive Imaging and Urinalysis of Immunotherapeutic Response in Renal Cell Carcinoma

Advanced Science, EarlyView.
This study reported renal‐clearable bio‐orthogonal near‐infrared fluorogenic probes (BGRs) that specifically imaging and urinalysis of granzyme B for dynamic evaluation of RCC immunotherapy. BGRs not only differentiate immunotherapeutic responses in orthotopic RCC mice, but also enable sensitive optical urinalysis of granzyme B in clinical specimens ...
Xingyue Yang, Baoshuai Liang, Liangmin Fu, Weiliang Deng, Yuyan Jiang, Weiping Xu, Jinwei Chen, Ya Zhou, Ke Wu, Jiaguo Huang   +9 more
wiley   +1 more source

MCC950 Alleviates Experimental Autoimmune Neuritis by Inhibiting NLRP3 Inflammasome Activity and Down-Regulating Interleukin-23/Interleukin-17 Axis Expression. [PDF]

J Inflamm Res
Li Y, Li X, Gu T, Wang L, Song M, Yang L, Huang Q, Yang J.   +7 more
europepmc   +1 more source

Biomimetic Polymerization of Tellurocysteine: Breaking the Natural Amino Acid Radioprotection Limitation

Advanced Science, EarlyView.
Inspired by natural amino acid polymer‐melanin systems, this study strategically incorporated tellurocysteine to develop advanced radiation‐shielding materials. This approach transformed the primary interaction mechanism between melanin‐based materials and incident photons from Compton scattering to the photoelectric effect. Tellurocysteine‐polymerized
Wei Chen, Hanjie Zhu, Yue Zhang, Yuqing Qiao, Ruotong Deng, Huaping Xu, Wei Cao   +6 more
wiley   +1 more source

Novel Cyclic Peptides as Interleukin-23 Inhibitor for Treating Inflammatory Disorders. [PDF]

ACS Med Chem Lett
Hu QL, Liang SH.
europepmc   +1 more source

Bioadhesive Hydrogel With Polyphenol‐Armored Nanogene Rejuvenates Chondrocyte Senescence for Aged Osteoarthritis Therapy

Advanced Science, EarlyView.
An adhesive hydrogel depot with polyphenol‐armored nanogenes is developed for treating aged osteoarthritis. This system maintains miR‐140 bioactivity, prolongs its intra‐articular retention, and enhances transfection into chondrocytes, leading to the downregulation of senescence‐associated pathways.
Liwei Yan, Runze Yang, Ting Zhou, Tianhao Xu, Yongqi Li, Yuelin Hu, Minghao Ge, Lei Zhang, Xiong Lu, Chaoming Xie, Weili Fu   +10 more
wiley   +1 more source

Interleukin 12/23 and interleukin 23 inhibitors for moderate-to-severe ulcerative colitis: a systematic review and network meta-analysis. [PDF]

Ann Gastroenterol
Sawaf B, Hayek MA, Kassem A, Alsoud D, Alom M, Salam AH, Shembesh RH, Beshr MS, Hallak Y, Abbarh S, Batikh E, Shibani M, Elhadi M, Alastal Y, Regueiro M.   +14 more
europepmc   +1 more source