Results 1 to 10 of about 558,043 (217)

The presence, severity, and onset of preeclampsia is associated with maternal interleukin-23 level: A case-control study [PDF]

International Journal of Reproductive BioMedicine, 2023
Background: Scientific evidence support that imbalance between inflammatory and anti-inflammatory cytokines play a critical role in preeclampsia (PE). Objective: To investigate the relationship between the maternal serum level of interleukin (IL)-23, a ...
Forough Forghani, Nasrin Ranjbar, Danial Jahantigh   +2 more
doaj   +2 more sources

Efficacy of interleukin-12/23 and interleukin-23 inhibitors in Hailey-Hailey disease [PDF]

JAAD Case Reports
Caroline Echeandia-Francis, BA, Xingyuan Jiang, MD, Ryland D. Mortlock, BS, Mohamad Goldust, MD, Leonard M. Milstone, MD, Keith A. Choate, MD, PhD   +5 more
doaj   +2 more sources

Levels of IL-23/IL-17 Axis in Plasma and Gingival Tissue of Periodontitis Patients According to the New Classification

Applied Sciences, 2022
Background: Periodontitis (P) is a chronic inflammatory disease characterized by the destruction of periodontium support tissue generated by different immuno-inflammatory mechanisms, including the RANK/RANKL/OPG and the IL-23/IL-17 axis.
Ruth Rodríguez-Montaño, Alondra del Carmen Ruiz-Gutiérrez, Vianeth María del Carmen Martínez-Rodríguez, Juan Ramón Gómez-Sandoval, Juan Manuel Guzmán-Flores, Julieta Sarai Becerra-Ruiz, Ana Lourdes Zamora-Perez, Celia Guerrero-Velázquez   +7 more
doaj   +1 more source

Interleukin-23 Inhibitors

Turkderm Turkish Archives of Dermatology and Venereology, 2022
For adult patients with moderate to severe plaque psoriasis scheduled for systemic therapy, FDA-approved agents that act via interleukin-23 (IL-23) inhibition are guselkumab, tildrakizumab, and risankizumab.
Esra Adışen
doaj   +1 more source

Circulating Interleukin-23 Levels in Rheumatoid Arthritis and its Relationship to Disease Activity: a Systematic Review with Meta-Analysis

مجله كليه طب الكندي, 2023
Background: Rheumatoid arthritis (RA) is a chronic and systemic autoimmune disease that is characterized by severe synovial inflammation, cartilage erosion, bone loss, and generalized vasculopathy.
Ahmed Azzam, Shaza Abdul Basset Abdul Basset, Heba Khaled, Neveen Refaey, Ahmed Atta Ahmed Ali, Saad abdelrahim saad shoulah, Mohammed Saleh Al Saifi, Mahmoud s.Meleha   +7 more
doaj   +1 more source

Decoding IL-23 Signaling Cascade for New Therapeutic Opportunities

Cells, 2020
The interleukin 23 (IL-23) is a key pro-inflammatory cytokine in the development of chronic inflammatory diseases, such as psoriasis, inflammatory bowel diseases, multiple sclerosis, or rheumatoid arthritis.
Gloria Pastor-Fernández, Isabel R. Mariblanca, María N. Navarro   +2 more
doaj   +1 more source

Prospects for the use of monoclonal antibodies to interleukin 23 Gusеlkumab in psoriatic arthritis: New data

Научно-практическая ревматология, 2022
Among the pathophysiological mechanisms of immune-mediated inflammatory diseases (IMIDs), specific attention has been paid to the abnormal activation of Th17 type immune response related to the dysregulated synthesis of cytokines forming the interleukin (
E. L. Nasonov, T. V. Korotaeva, S. Rodolfi, C. F. Selmi   +3 more
doaj   +1 more source

Current concepts in the pathogenesis of spondyloarthritis

Indian Journal of Rheumatology, 2020
Pathogenesis of spondyloarthritis (SpA) is multifactorial and still not understood entirely. The role of genetics including human leukocyte antigen B27 has been investigated extensively, which along with genome-wide association studies has helped us ...
Nibha Jain, Arumugam Moorthy
doaj   +1 more source

Microglia-Derived Interleukin 23: A Crucial Cytokine in Alzheimer's Disease?

Frontiers in Neurology, 2021
Neuronal cell death, amyloid β plaque formation and development of neurofibrillary tangles are among the characteristics of Alzheimer's disease (AD). In addition to neurodegeneration, inflammatory processes such as activation of microglia and astrocytes ...
Louisa Nitsch, Linda Schneider, Julian Zimmermann, Marcus Müller   +3 more
doaj   +1 more source

PROBLEMS OF SPONDYLOARTHRITIS IN THE PROCEEDINGS OF THE EULAR-2013 CONGRESS (MADRID, 12–15 JUNE 2013)

Научно-практическая ревматология, 2014
The EULAR-2013 Congress took place in Madrid on 12–15 June 2013. The problem of spondyloarthritis (SA) was one of the significant aspects at this scientific forum.
Sh. F. Erdes
doaj   +1 more source