Results 21 to 30 of about 535,272 (262)
The Role of Interleukin-17 in Juvenile Idiopathic Arthritis: From Pathogenesis to Treatment
Medicina, 2022 Background and Objectives: Interleukin-17 (IL-17) is a cytokine family consisting of six members and five specific receptors. IL-17A was the first member to be identified in 1993.
Marino Paroli +5 more
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Interleukin-27 and interleukin-23 modulate human plasmacell functions [PDF]
Journal of Leukocyte Biology, 2011 ABSTRACTThis study tested the hypothesis that IL-27 and IL-23, two heterodimeric cytokines involved in physiological immune responses and immunological disorders, may function on human PC and plasmablasts. It was reported that IL-27 acts on human mature B cells, but the role of IL-27 and IL-23 in human PC remains to be established.
Claudia, Cocco +2 more
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Acta Medica Bulgarica, 2022 In this manuscript we are discussing our research of the presence of single nucleotide polymorphisms (SNPs) of two proinflammatory cytokines – interleukin 17F (IF-17F) and interleukin 23 (IL-23) in a cohort of Bulgarian patients.
Pashova-Tasseva Z. +3 more
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Serum Levels of Interleukin - 23 and Interleukin - 17 in Hashimoto’s Thyroiditis [PDF]
Acta Endocrinologica (Bucharest), 2019 Overproduction of proinflammatory cytokines plays a significant role in the pathogenesis of Hashimoto's thyroiditis (HT). Recent studies revealed a prominent role of newly discovered Th17 subset in the induction of autoimmune disorders and that the signaling induced by IL-23 on Th17 cells is crucial to obtain a pathogenic and sustained phenotype.
J, Gerenova, I, Manolova, S, Stanilova
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Differential Roles for Interleukin-23 and Interleukin-17 in Intestinal Immunoregulation [PDF]
Immunity, 2015 Interleukin-23 (IL-23) and IL-17 are cytokines currently being targeted in clinical trials. Although inhibition of both of these cytokines is effective for treating psoriasis, IL-12 and IL-23 p40 inhibition attenuates Crohn's disease, whereas IL-17A or IL-17 receptor A (IL-17RA) inhibition exacerbates Crohn's disease.
Maxwell, Joseph R. +12 more
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Allergology International, 2015 Background: The role of interleukin (IL)-23 in asthma pathophysiology is still controversial. We examined its role in allergic airway inflammation in response to two distinct antigens using IL-23-deficient mice.
Rika Ogawa +9 more
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Expressions of IL-17, IL-21 and IL-23 in the serum of allergic rhinitis patients [PDF]
Journal of Medical Biochemistry, 2011 The present study aimed to investigate the expressions of interleukin-17 (IL-17), IL-21 and IL-23 in the serum of allergic rhinitis (AR) patients and to explore their relationship with special IgE (sFgE) in the serum.
Huang Xuekun +5 more
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IL-23 Gene and Protein Expression in Childhood Asthma [PDF]
Iranian Journal of Immunology, 2017 Background: Asthma is the chronic inflammation of airways characterized by eosinophilic infiltration, mucus overproduction, airway hyper-responsiveness and airway remodeling.
Soheila Alyasin +6 more
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Клиническая и экспериментальная тиреоидология, 2018 Background. Endocrine ophthalmopathy (EOP) is an autoimmune orbit disease characterized by soft retrobulbar tissues damage. The level of antibodies to the thyroid-stimulating hormone receptor (TSHRAbs) is considered as alaboratory marker of EOP activity.
Svetlana V. Charinzeva +1 more
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Iranian Journal of Parasitology, 2020 Background: The possible risk factor of Toxoplasma infection and its possible correlation with Interleukin-12 (IL-12) and Interleukin-23 (IL-23) in breast cancer patients was investigated. Methods: Overall, 190 female patients referred to the Oncology
Maha Mustafa ASSIM, Entsar Jabbar SAHEB
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