Results 31 to 40 of about 3,836,717 (246)

Interleukin 23 and Interleukin 17 Evaluation Before and After Methotrexate Treatment of Basal Cell Carcinoma [PDF]

Zagazig University Medical Journal
Background: Interleukin 23 (IL 23) and Interleukin 17 (IL 17) are two vital cytokines encountered in cutaneous and non-cutaneous immune-mediated inflammatory conditions and also share in cancer development. Basal cell carcinoma (BCC) is a well-known skin
Dina Esmat, Kamal ElKashishy, Nelly Said, Shrook Khashaba, Ahmed Elgarf   +4 more
doaj   +1 more source

Proinflammatory Cytokine Polymorphisms and Severity of Periodontitis in a Cohort of Bulgarian Patients

Acta Medica Bulgarica, 2022
In this manuscript we are discussing our research of the presence of single nucleotide polymorphisms (SNPs) of two proinflammatory cytokines – interleukin 17F (IF-17F) and interleukin 23 (IL-23) in a cohort of Bulgarian patients.
Pashova-Tasseva Z., Popova Ch., Tosheva E., Mlachkova A.   +3 more
doaj   +1 more source

IL-23 Gene and Protein Expression in Childhood Asthma [PDF]

Iranian Journal of Immunology, 2017
Background: Asthma is the chronic inflammation of airways characterized by eosinophilic infiltration, mucus overproduction, airway hyper-responsiveness and airway remodeling.
Soheila Alyasin, Reza Amin, Ali Fazel, Mohammad Hossein Karimi, Seyed Hesamedin Nabavizadeh, Hossein Esmaeilzadeh, Maryam Babaei   +6 more
doaj  

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Comparative Efficacy and Safety of Interleukin-23 and Interleukin-12/23 Inhibitors in the Induction and Maintenance Phases of Crohn’s Disease: A Systematic Review and Network Meta-Analysis

Российский журнал гастроэнтерологии, гепатологии, колопроктологии
Aim. To compare the efficacy and safety of interleukin (IL)-23 and IL-12/23 inhibitors during the induction and maintenance phases of Crohn’s disease using a Bayesian network meta-analysis.Materials and methods.
S. Alvianto, V. N. Muzellina, N. D. Widjanarko, O. Wangidjaja   +3 more
doaj   +1 more source

Th17 Lymphocytes in Respiratory Syncytial Virus Infection

Viruses, 2013
Infection by respiratory syncytial virus (RSV) affects approximately 33 million infants annually worldwide and is a major cause of hospitalizations. Helper T lymphocytes (Th) play a central role in the immune response during such infections.
Rizgar A. Mageed, Ali S. Jawad, Mohammed Al-Bogami, Nasra Al-Adhoubi, Jonas Bystrom   +4 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Review of ustekinumab, an interleukin-12 and interleukin-23 inhibitor used for the treatment of plaque psoriasis

, 2010
Nora Koutruba, Jason Emer, Mark LebwohlMount Sinai School of Medicine, New York, USAAbstract: The pathogenesis of psoriasis is unknown, although it is generally accepted that this chronic inflammatory skin disorder is a complex autoimmune condition ...
Nora Koutruba, Jason Emer, Mark Lebwohl
core   +1 more source

IL-23 contributes to control of chronic Helicobacter pylori infection and the development of T helper responses in a mouse model

Frontiers in Immunology, 2012
The immune response to Helicobacter pylori involves a mixed T helper-1, T helper-2, and T helper-17 response. It has been suggested that T helper cells contribute to the gastric inflammatory response during infection, and that T helper 1 (Th1) and T ...
Dennis J Horvath, Mary Kay Washington, Vicki A Cope, Holly Marie Scott Algood, Holly Marie Scott Algood   +4 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source