Results 51 to 60 of about 541,619 (302)
Impact of Brucellosis on Interleukin -23 Level, Acid Phosphates and Some Other Trace Elements
, 2018 The study was carried out during a period of February 2017-July 2018 for the detection of brucellosis in 128 suspected patients with age group range from 17 - 69 years, who attended to Baghdad teaching hospitals, that had been examined and defined as ...
Ghada Ibrahim Taha +6 more
core +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
The inflammatory cytokine interleukin-23 is elevated in lung cancer, particularly small cell type
, 2016 Aim of the study: Interleukin (IL)-17 and IL-23 play roles in inflammation and autoimmunity. The function of the IL-17/IL-23 pathway has not been completely evaluated in cancer patients.
Tuba Muftuoglu +8 more
core +1 more source
Validation of an automated enzyme immunoassay for interleukin-6 for routine clinical use [PDF]
, 1998 Serum levels of Interleukin-6 (IL-6), a proinflammatory cytokine, are increased in early stages of inflammatory diseases such as infection and sepsis. Assay systems which permit its measurement within a few hours and as a single measurement have not been
Peter Fraunberger +17 more
core +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
The molecular basis of chaperone-mediated interleukin 23 assembly control
Nature Communications, 2019 It is unclear how unassembled secretory pathway proteins are discriminated from misfolded ones. Here the authors combine biophysical and cellular experiments to study the folding of heterodimeric interleukin 23 and describe how ER chaperones recognize ...
Susanne Meier +12 more
doaj +1 more source
Клиническая и экспериментальная тиреоидология, 2018 Background. Endocrine ophthalmopathy (EOP) is an autoimmune orbit disease characterized by soft retrobulbar tissues damage. The level of antibodies to the thyroid-stimulating hormone receptor (TSHRAbs) is considered as alaboratory marker of EOP activity.
Svetlana V. Charinzeva +1 more
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Interleukin-12/23 Inhibitors: Ustekinumab
, 2016 Inhibitors of interleukin-12/23 (IL-12/23) are compounds which bind to both IL-12 and IL-23 and inactivate them.
Mahler, Stephen M. +7 more
core +1 more source
Interleukin-1 regulates multiple atherogenic mechanisms in response to fat feeding [PDF]
, 2009 Background: Atherosclerosis is an inflammatory process that develops in individuals with known risk factors that include hypertension and hyperlipidaemia, influenced by diet.
Dower, S. +25 more
core +1 more source