Results 11 to 20 of about 535,272 (262)
Current concepts in the pathogenesis of spondyloarthritis
Indian Journal of Rheumatology, 2020 Pathogenesis of spondyloarthritis (SpA) is multifactorial and still not understood entirely. The role of genetics including human leukocyte antigen B27 has been investigated extensively, which along with genome-wide association studies has helped us ...
Nibha Jain, Arumugam Moorthy
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Interleukin 23 Levels Are Increased in Carotid Atherosclerosis [PDF]
Stroke, 2015 Background and Purpose— Interleukin (IL)-23 is a cytokine in the IL-12 family, mainly produced by antigen-presenting cells with a central role in inflammation. We hypothesize that IL-23 is also important in atherogenesis and investigate this in a population with carotid atherosclerosis. Methods—
Abbas, Azhar +18 more
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Microglia-Derived Interleukin 23: A Crucial Cytokine in Alzheimer's Disease?
Frontiers in Neurology, 2021 Neuronal cell death, amyloid β plaque formation and development of neurofibrillary tangles are among the characteristics of Alzheimer's disease (AD). In addition to neurodegeneration, inflammatory processes such as activation of microglia and astrocytes ...
Louisa Nitsch +3 more
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Journal of Investigative Surgery, 2021 Background Idiopathic Granulomatous Mastitis (IGM) is a benign chronic inflammatory breast disease that mimics breast cancer, and the etiopathogenesis has not yet been fully evaluated. Autoimmunity has received the most focus as a possible etiology.
Mehmet Saydam +8 more
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Научно-практическая ревматология, 2014 The EULAR-2013 Congress took place in Madrid on 12–15 June 2013. The problem of spondyloarthritis (SA) was one of the significant aspects at this scientific forum.
Sh. F. Erdes
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Interleukin-17A and interleukin-23 in morphea
Archives of Medical Science, 2012 Morphea is a disease included in the group of scleroderma type autoimmune diseases. Interleukin (IL)-17A may play a role at every stage of its pathogenesis. The study aimed at evaluation of IL-17A and IL-23 (as the main cytokine which is supposed to stimulate and maintain synthesis of IL-17) in pathogenesis of morphea.The studies were performed on 41 ...
Dańczak-Pazdrowska, Aleksandra +9 more
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Kaohsiung Journal of Medical Sciences, 2023 The interleukin‐23 (IL‐23)/IL‐17 immune axis has been linked to the pathology of psoriasis, but how this axis contributes to skin inflammation in this disease remains unclear. We measured inflammatory cytokines associated with the IL‐23/IL‐17 immune axis
Wen‐Cheng Chen +6 more
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Analysis of Interleukin-17, Interleukin-23, neopterin and Nesfatin-1 levels in the sera of Hashimoto patients [PDF]
Journal of Medical Biochemistry, 2023 Background: Hashimoto's thyroiditis (HT) is an autoimmune disorder affecting the thyroid gland and may present as goiter or atrophic thyroiditis that may result in various metabolic and inflammatory disorders.
Bayraktar Nihayet +4 more
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Interleukin 23 in the skin: role in psoriasis pathogenesis and selective interleukin 23 blockade as treatment [PDF]
Therapeutic Advances in Chronic Disease, 2018 Plaque psoriasis is one of the most common autoimmune skin diseases and is characterized by erythematous, scaly plaques. Many highly effective, targeted therapies have been developed as a result of an improved understanding of the pathogenesis of psoriasis.
Tom C, Chan +2 more
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Risk of Cutaneous T Cell Lymphoma with Psoriasis Biologic Therapies
Dermatology and Therapy, 2023 Background The risk of developing cutaneous T cell lymphoma (CTCL) in patients using psoriasis biologics has not been well characterized. The goals of this review were to investigate the incidence of CTCL in patients with psoriasis receiving biologic ...
Mitchell S. Davis +7 more
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