Results 11 to 20 of about 541,619 (302)
Interleukin 23 Levels Are Increased in Carotid Atherosclerosis [PDF]
Stroke, 2015 Background and Purpose— Interleukin (IL)-23 is a cytokine in the IL-12 family, mainly produced by antigen-presenting cells with a central role in inflammation. We hypothesize that IL-23 is also important in atherogenesis and investigate this in a population with carotid atherosclerosis. Methods—
Abbas, Azhar +18 more
openaire +4 more sources
The Interleukin‐23 / Interleukin‐17 axis in intestinal inflammation
Journal of Internal Medicine, 2008 Abstract.Although the precise aetiology of inflammatory bowel disease (IBD) remains unclear, recent discoveries have led to an improved understanding of disease pathogenesis. Whilst these findings have underscored the central role of innate and adaptive immune responses in intestinal inflammation, they have also precipitated a paradigm shift in the key
Maloy, Kevin +2 more
openaire +3 more sources
The interleukin‐23 axis in intestinal inflammation
Immunological Reviews, 2008 Summary: Immune responses in the intestine are tightly regulated to ensure host protective immunity in the absence of immune pathology. Interleukin‐23 (IL‐23) has recently been shown to be a key player in influencing the balance between tolerance and immunity in the intestine.
Ahern, P, Izcue, A, Maloy, K, Powrie, F
openaire +3 more sources
Use of NanoBiT and NanoBRET to characterise interleukin-23 receptor dimer formation in living cells. [PDF]
Br J Pharmacol, 2023 Background and Purpose: Interleukin-23 (IL-23) and its receptor are important drug targets for the treatment of auto-inflammatory diseases. IL-23 binds to a receptor complex composed of two single transmembrane spanning proteins IL23R and IL12Rβ1.
Lay CS +3 more
europepmc +2 more sources
Significance of Interleukin 23 in Systemic Lupus Patients: Relation to Disease Activity and Damage Indices. [PDF]
Biologics, 2023 Maysa M Haroon,1 Gehan A Hegazy,2,3 Mohammed A Hassanien,4,5 Olfat Shaker,6 Wafaa H Hussein1 1Department of Rheumatology, Faculty of Medicine, Cairo University, Cairo, Egypt; 2Clinical Biochemistry Department, Faculty of Medicine, King Abdulaziz ...
Haroon MM +4 more
europepmc +2 more sources
Current concepts in the pathogenesis of spondyloarthritis
Indian Journal of Rheumatology, 2020 Pathogenesis of spondyloarthritis (SpA) is multifactorial and still not understood entirely. The role of genetics including human leukocyte antigen B27 has been investigated extensively, which along with genome-wide association studies has helped us ...
Nibha Jain, Arumugam Moorthy
doaj +1 more source
Interleukin-23 Involved in Fibrotic Autoimmune Diseases: New Discoveries. [PDF]
J Clin Med, 2023 Interleukin (IL)-23 is a central pro-inflammatory cytokine with a broad range of effects on immune responses. IL-23 is pathologically linked to the induction of the production of the pro-inflammatory cytokines IL-17 and IL-22, which stimulate the ...
Sisto M, Lisi S.
europepmc +2 more sources
Microglia-Derived Interleukin 23: A Crucial Cytokine in Alzheimer's Disease?
Frontiers in Neurology, 2021 Neuronal cell death, amyloid β plaque formation and development of neurofibrillary tangles are among the characteristics of Alzheimer's disease (AD). In addition to neurodegeneration, inflammatory processes such as activation of microglia and astrocytes ...
Louisa Nitsch +3 more
doaj +1 more source
Regulation of Interleukin-23 Receptor expression in human T-Lymphocytes [PDF]
, 2022 openChronic inflammatory diseases (CID) are clinically heterogeneous conditions that share common inflammatory pathways and derive from aberrant immune responses.
CREMA, ALESSIA
core
Journal of Investigative Surgery, 2021 Background Idiopathic Granulomatous Mastitis (IGM) is a benign chronic inflammatory breast disease that mimics breast cancer, and the etiopathogenesis has not yet been fully evaluated. Autoimmunity has received the most focus as a possible etiology.
Mehmet Saydam +8 more
doaj +1 more source