Results 11 to 20 of about 139,988 (286)
Serum levels of inflammatory mediators as prognostic biomarker in silica exposed workers
Scientific Reports, 2021 Silicosis is a diffuse interstitial lung disease caused by sustained inhalation of silica and silicates. Several cytokines are activated by their inhalation and can mediate the process of pulmonary fibrosis.
José Jesús Blanco-Pérez +8 more
doaj +1 more source
Siberian Medical Review, 2022 The aim of the research. To assess the role of matrix metalloproteinase-2 (MMP-2) and the alpha subunit of the interleukin-2 receptor (IL-2 Ra) in development of critical illness in pneumonia patients with underlying influenza A (H1N1). Material and methods. A total of 85 patients with pneumonia associated with influenza A (H1N1) were examined.
A.V. Malyarchikov, K.G. Shаpovаlov
openaire +1 more source
Agriculture, 2023 This study examined the genes related to immunity, metabolism, and antioxidants that may interact with the prevalence of postpartum endometritis in Ossimi sheep. We used fifty endometritis-positive Ossimi sheep and fifty that appeared to be normal.
Fatmah A. Safhi, Ahmed Ateya
doaj +1 more source
Phenotypic knockout of the high-affinity human interleukin 2 receptor by intracellular single-chain antibodies against the alpha subunit of the receptor. [PDF]
Proceedings of the National Academy of Sciences, 1995 The experimental manipulation of peptide growth hormones and their cellular receptors is central to understanding the pathways governing cellular signaling and growth control. Previous work has shown that intracellular antibodies targeted to the endoplasmic reticulum (ER) can be used to capture specific proteins as they enter the ER, preventing their ...
J H, Richardson +3 more
openaire +2 more sources
Repurposing drugs to target nonalcoholic steatohepatitis [PDF]
, 2019 Nonalcoholic fatty liver disease (NAFLD) is a complex disorder that has evolved in recent years as the leading global cause of chronic liver damage.
Pirola, Carlos José +1 more
core +1 more source
The TLR4 D299G and T399I SNPs Are Constitutively Active to Up-Regulate Expression of Trif-Dependent Genes [PDF]
, 2014 Peer reviewedPublisher ...
Berry, Susan +8 more
core +12 more sources
Aquaculture Reports, 2020 Red-spotted grouper nervous necrosis virus (RGNNV) has threatened aquaculture of the Asian seabass (Lates calcarifer) in many countries of the Asia-Pacific for decades. To understand the pathogenesis of RGNNV, a transcriptome analysis of the head kidney,
Kitipong Angsujinda +4 more
doaj +1 more source
Frontiers in Immunology, 2023 BackgroundIncreasing evidence shows that systemic inflammation is an embedded mechanism of proliferative diabetic retinopathy (PDR). However, the specific systemic inflammatory factors involved in this process remained obscure.
Qiqin Shi +4 more
doaj +1 more source
Crohn's disease: Th1, Th17 or both? The change of a paradigm: new immunological and genetic insights implicate Th17 cells in the pathogenesis of Crohn's disease [PDF]
, 2009 Traditionally, Crohn's disease has been associated with a Th1 cytokine profile, while Th2 cytokines are modulators of ulcerative colitis. This concept has been challenged by the description of tolerising regulatory T cells (Treg) and by proinflammatory ...
Brand, Stephan
core +1 more source
Frontiers in Immunology, 2022 BackgroundPemphigus vulgaris (PV) is a kind of IgG-mediated autoimmune blistering disease (AIBD) that is characterized by loss of keratinocyte adhesion in the epithelium of mucous membranes or skin.
Siji Chen +4 more
doaj +1 more source