Results 251 to 260 of about 139,988 (286)

Epigenome-Wide Search for Distinctive Methylation Biomarkers of Endothelial and Leukocyte DNA. [PDF]

Epigenomes
Korolenya VA, Filipenko ML, Smetanina MA.   +2 more
europepmc   +1 more source

Targeting the Epithelial Alarmin Axis with Biomedical Nanoparticles: A New Frontier in Allergic Asthma Therapy. [PDF]

Int J Nanomedicine
Yang Y.
europepmc   +1 more source

Comparative analysis of adipose-, bone marrow-, and amniotic membrane-derived MSC secretomes and EVs reveals shared and source-specific therapeutic signatures for osteoarthritis. [PDF]

Extracell Vesicles Circ Nucl Acids
Ragni E, Papait A, Taiana MM, Luca P, Grieco G, Vertua E, Romele P, Silini AR, Parolini O, de Girolamo L.   +9 more
europepmc   +1 more source

Possible mechanism for the alpha subunit of the interleukin‐2 receptor (CD25) to influence interleukin‐2 receptor signal transduction [PDF]

Immunology & Cell Biology, 2002
The receptors for interleukin 2 (IL‐2) and interleukin 15 (IL‐15) in T cells share the IL‐2Rβ subunit (CD122) and γC subunit but have private α subunits. Despite utilizing the same receptor chains known to be necessary and sufficient to transduce IL‐2 signals the two cytokines manifest different cellular effects.
Ellery, Jonathan M., Nicholls, Peter J.
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An exon 5-deleted mrna encodes a functional interleukin 2 receptor alpha-subunit

Biochemical and Biophysical Research Communications, 1991
Two polypeptides are involved in interleukin 2 binding: a low-affinity receptor of 55 kD (IL2-R alpha) and an intermediate affinity component of 75 kD (IL2-R beta). We describe the cloning by the Polymerase Chain Reaction of the coding region of IL2-R alpha from a human T-cell lymphoma cell line.
L, Mercken, V, Moras, L, Hemon, B, Lionne, A, Bousseau, A, Dautry-Varsat, M, Collins, J F, Mayaux   +7 more
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USE OF AN ANTIBODY AGAINST THE SOLUBLE INTERLEUKIN 2 RECEPTOR α SUBUNIT CAN MODULATE THE STABILITY AND BIODISTRIBUTION OF INTERLEUKIN-2

Cytokine, 1999
The authors have previously reported that the soluble serum form of the alpha subunit of the IL-2 receptor (sIL-2Ralpha), whose natural half-life is approximately 40 min, survived much longer in the circulation when bound by a specific antibody. In the present study, the authors evaluated the extent to which sIL-2Ralpha protected IL-2 in freshly ...
H, Kobayashi, Y, Tagaya, E S, Han, I S, Kim, N, Le, C H, Paik, I, Pastan, D L, Nelson, T A, Waldmann, J A, Carrasquillo   +9 more
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Glucocorticoid-mediated inhibition of interleukin-2 receptor α and -β subunit expression by human T cells

Immunopharmacology, 1994
To determine the mechanism of glucocorticoid (GC)-mediated inhibition of T cell functions, the effect of dexamethasone (DM) on T cell proliferation and interleukin-2 receptor (IL-2R) generation were studied. Dexamethasone inhibited IL-2-induced T cell proliferation by 30%-88%, relative to its concentration within the cultures.
O A, Batuman, A P, Ferrero, A, Diaz, B, Berger, R J, Pomerantz   +4 more
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Cyclosporin A Upmodulates the α-Subunit of the Interleukin-2 Receptor and the Metastatic Ability of Murine B16F10 Melanoma Cells

Invasion and Metastasis, 1998
In the present study, the effect of in vitro cyclosporin A (CsA) treatment on IL-2R expression and the metastatic behavior of B16F10 melanoma cells has been reported. CsA treatment was found to increase the percentage of B16F10 cells expressing the α-subunit of IL-2R on the cell surface and also at the mRNA level.
M D, Boyano, A G, de Galdeano, M D, García-Vázquez, A, Alvarez, M, Luz Cañavate   +4 more
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Immunohistochemical localization of interleukin-2 and its receptor subunits α, β and γ in the main olfactory bulb of the rat

Brain Research, 2001
Endogenous interleukin-2 (IL-2) was found in the adult rat brain, however, it has not been reported whether this cytokine is present in the olfactory bulb. Immunohistochemical techniques were used to examine the cellular localization of IL-2 and its receptor subunits in the main olfactory bulb of the rat.
G, Wang, C, Lu, H, Liu, W, Jin, X, Jiao, G, Wei, J, Chen, Y, Zhu   +7 more
openaire   +2 more sources