HpARI Protein Secreted by a Helminth Parasite Suppresses Interleukin-33 [PDF]
Immunity, 2017 &NA; Infection by helminth parasites is associated with amelioration of allergic reactivity, but mechanistic insights into this association are lacking.
Megan Osbourn +23 more
semanticscholar +9 more sources
Interleukin‐33‐Mediated Mechanical‐Loading Induced Degeneration of Knee Joint Chondrocytes [PDF]
FASEB BioAdvancesOsteoarthritis (OA), a common degenerative joint disorder, continued to present significant challenges in clinical management due to an incomplete understanding of its pathogenesis.
Jiahui Zhang +5 more
doaj +2 more sources
Interleukin-33 (IL-33) promotes DNA damage-resistance in lung cancer [PDF]
Cell Death and DiseaseResistance to DNA damage is one of the primary mechanisms by which tumor cells evade the effects of standard chemotherapeutic agents and radiotherapy. Dynamic and complex interactions between the tumor microenvironment (TME) and tumor cells critically ...
Haoge Luo +7 more
doaj +2 more sources
Interleukin-33 produced by M2 macrophages and other immune cells contributes to Th2 immune reaction of IgG4-related disease [PDF]
Scientific Reports, 2017 IgG4-related disease (IgG4-RD) is characterized by elevated serum IgG4 and marked infiltration of IgG4-positive cells in multiple organs. Interleukin-33 (IL-33) is a recently described cytokine that is secreted by damaged epithelial cells, macrophages ...
S. Furukawa +12 more
semanticscholar +2 more sources
Interleukin-33 in cutaneous wound healing
European Journal of InflammationBarrier tissues like the skin, gastrointestinal tract, and respiratory system exhibit high IL-33 expression. IL-33 expression increases in humans and mice during cutaneous wound healing.
Bei Liu
doaj +2 more sources
Biological mechanisms and therapeutic prospects of interleukin-33 in pathogenesis and treatment of allergic disease [PDF]
Journal of InflammationAllergic diseases significantly impact the quality of life of people around the world. Cytokines play a crucial role in regulating the immune system. Due to their importance in pro-inflammatory mechanisms, cytokines are used to understand pathogenesis ...
Mohammad Chand Jamali +10 more
doaj +2 more sources
Interleukin-33 regulates the functional state of microglia
Frontiers in Cellular Neuroscience, 2022 Microglia, the most prominent resident immune cells, exhibit multiple functional states beyond their immunomodulatory roles. Non-immune functions such as synaptic reorganization, removal of cellular debris, and deposition of abnormal substances are ...
Tianqing Xiong +5 more
doaj +3 more sources
Interleukin-33 and ST2 Signaling in Tumor Microenvironment [PDF]
Journal of Interferon & Cytokine Research, 2019 Interleukin-33 (IL-33) is one of the members of the IL-1 family of cytokines and a ligand of ST2 and IL-1 receptor accessory protein (IL-1RAcP) that is known to affect Th2 inflammatory response with partial effects on Th1 responses.
Jaewoo Hong, Soohyun Kim, P. Charles Lin
semanticscholar +3 more sources
Interleukin-33: Its Emerging Role in Allergic Diseases [PDF]
Molecules, 2018 Allergic diseases, which include asthma, allergic rhinitis (AR), chronic rhinosinusitis (CRS), atopic dermatitis (AD), food allergy (FA), allergic keratoconjunctivitis, seriously affect the quality of life of people all over the world.
Wen Ding +5 more
doaj +3 more sources
Higher interleukin-33 levels in aggressive periodontitis cases
Journal of Indian Society of Periodontology, 2019 Context: Interleukin-33 (IL-33) is a novel alarmin that warns immune cells of tissue destruction in injury or infection. Aims: This study is aimed at analyzing and correlating the concentration of IL-33 in the gingival crevicular fluid (GCF) and plasma ...
Sujatha Pai Ballambettu +3 more
doaj +3 more sources