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INTERLEUKIN 33 AND FIBROSIS: PATHOGENESIS UPDATED

Медицинская иммунология, 2018
Interleukin 33 (IL-33) is a member of the IL-1 family, which is widely expressed on all types of cells. IL-33 was identified as a functional ligand for the plasma membrane receptor complex, which is a heterodimer consisting of a membrane bound ST2 ...
E. G. Uchasova, O. V. Gruzdeva, Yu. A. Dileva, V. N. Karetnikova   +3 more
doaj   +3 more sources

Hippocampal interleukin-33 mediates neuroinflammation-induced cognitive impairments [PDF]

Journal of Neuroinflammation, 2020
Background Interleukin (IL)-33 is expressed in a healthy brain and plays a pivotal role in several neuropathologies, as protective or contributing to the development of cerebral diseases associated with cognitive impairments.
Flora Reverchon, Vidian de Concini, Vanessa Larrigaldie, Sulayman Benmerzoug, Sylvain Briault, Dieudonnée Togbé, Bernhard Ryffel, Valérie F. J. Quesniaux, Arnaud Menuet   +8 more
doaj   +5 more sources

Interleukin-33 regulates the functional state of microglia

Frontiers in Cellular Neuroscience, 2022
Microglia, the most prominent resident immune cells, exhibit multiple functional states beyond their immunomodulatory roles. Non-immune functions such as synaptic reorganization, removal of cellular debris, and deposition of abnormal substances are ...
Tianqing Xiong, Tianqing Xiong, Xingyi Wang, Yiwen Zha, Yingge Wang, Yingge Wang   +5 more
doaj   +3 more sources

Interleukin-33 in cutaneous wound healing

European Journal of Inflammation
Barrier tissues like the skin, gastrointestinal tract, and respiratory system exhibit high IL-33 expression. IL-33 expression increases in humans and mice during cutaneous wound healing.
Bei Liu
doaj   +2 more sources

Interleukin-33: Its Emerging Role in Allergic Diseases [PDF]

Molecules, 2018
Allergic diseases, which include asthma, allergic rhinitis (AR), chronic rhinosinusitis (CRS), atopic dermatitis (AD), food allergy (FA), allergic keratoconjunctivitis, seriously affect the quality of life of people all over the world.
Wen Ding, Gui-Lin Zou, Wei Zhang, Xing-Ning Lai, Hou-Wen Chen, Li-Xia Xiong   +5 more
doaj   +3 more sources

Higher interleukin-33 levels in aggressive periodontitis cases

Journal of Indian Society of Periodontology, 2019
Context: Interleukin-33 (IL-33) is a novel alarmin that warns immune cells of tissue destruction in injury or infection. Aims: This study is aimed at analyzing and correlating the concentration of IL-33 in the gingival crevicular fluid (GCF) and plasma ...
Sujatha Pai Ballambettu, A R Pradeep, Meera Purushottam, Somdatta Sen   +3 more
doaj   +3 more sources

Interleukin-33 in Systemic Sclerosis: Expression and Pathogenesis

Frontiers in Immunology, 2018
Interleukin-33 (IL-33), a member of the IL-1 superfamily, functions as a traditional cytokine and nuclear factor. It is proposed to have an “alarmin” role. IL-33 mediates biological effects by interacting with the ST2 receptor and IL-1 receptor accessory
Liya Li, Liya Li, Honglin Zhu, Honglin Zhu, Xiaoxia Zuo, Xiaoxia Zuo   +5 more
doaj   +3 more sources

Interleukin 33: a suitable target for biological therapies of COPD? [PDF]

ERJ Open Research
Corrado Pelaia
doaj   +2 more sources

Phase I Study of the Anti-interleukin 33 Fragment Antigen-Binding Region RO7303359 in Geographic Atrophy Secondary to Age-Related Macular Degeneration. [PDF]

Ophthalmol Sci
Pearlman JA, Sheth VS, Khanani AM, Indjeian VB, Brunstein F, Kuruvilla D, Maia M, Dere R, Ma L, Chen H, Datta S, Willis JR, Wiley HE.   +12 more
europepmc   +2 more sources

Publisher Correction: Exploring the significance of interleukin-33/ST2 axis in minimal change disease. [PDF]

Sci Rep, 2023
Kanazawa N, Iyoda M, Suzuki T, Tachibana S, Nagashima R, Honda H.   +5 more
europepmc   +3 more sources