ST2 in Stable and Unstable Ischemic Heart Diseases [PDF]
, 2015 Circulating suppression of tumorigenicity 2 (ST2) predicts cardiovascular outcomes and mortality in ischemic heart disease (IHD). ST2 does not correlate with traditional risk indicators as closely as N-terminal pro–brain natriuretic peptide (NT-proBNP ...
DI SOMMA, Salvatore +2 more
core +1 more source
Role of interleukins in heart failure with reduced ejection fraction
Anatolian Journal of Cardiology, 2019 Heart failure (HF) is the leading cause of morbidity and mortality in developed countries, and it is the primary cause of mortality in the elderly worldwide.
Oliwia Anna Segiet +4 more
doaj +1 more source
IL-25 and IL-33 Serum Levels are not Associated with the Type of Allergen Causing Allergic Rhinitis [PDF]
Iranian Journal of Immunology, 2019 Background: Fungal aeroallergens might sensitize the airway which in turn produces a specific cytokine profile. Objective: To evaluate the IL-25 and IL-33 profile in patients with fungal allergic rhinitis. Methods: The present study examined patients who
Reza Abbasi +6 more
doaj +1 more source
HpARI protein secreted by a helminth parasite suppresses interleukin-33 [PDF]
, 2017 Infection by helminth parasites is associated with amelioration of allergic reactivity, but mechanistic insights into this association are lacking.
Alasdair C. Ivens +84 more
core +7 more sources
A Multi-marker Model for Predicting Decompensated Heart Failure in Patients with Prior Acute Myocardial Infarction [PDF]
, 2020 The aim of the study was to assess the prognostic value of determining the plasma concentration of NT-proBNP and ST2 in the patients with decompensated HF and prior acute myocardial infarction and their combination in this category of patients.Materials ...
Levandovska, K. (Khrystyna)
core +3 more sources
Interleukin 33 expression in human arthritis [PDF]
Annals of the Rheumatic Diseases, 2011 Background and objectives Interleukin 33 (IL-33) is the most recently discovered member of the IL-1 family of cytokines. Recent evidence in human and mouse suggests a role for IL-33 and its receptor T1/ST2 in arthritis. In this study, the authors quantified IL-33 levels in serum and synovial fluid (SF), and assessed synovial IL-33 expression levels ...
Dominique Talabot-Ayer +6 more
openaire +1 more source
Cancer Cell International, 2018 Background Emerging evidence has suggested that interleukin (IL)-33 and its primary functional receptor ST2 are involved in the pathogenesis of tumorigenesis.
Guanglin Cui +5 more
doaj +1 more source
Comparison between soluble ST2 and high-sensitivity troponin I in predicting short-term mortality for patients presenting to the Emergency Department with chest pain [PDF]
, 2016 Background: High-sensitivity cardiac troponin I (hs-cTnI) and the soluble isoform of suppression of tumorigenicity 2 (sST2) are useful prognostic biomarkers in acute coronary syndrome (ACS).
Francesca Orsini +8 more
core +1 more source
The role of interleukin-33 in organ fibrosis
Discovery Immunology, 2022 Summary Interleukin (IL)-33 is highly expressed in the nucleus of cells present at barrier sites and signals via the ST2 receptor. IL-33 signalling via ST2 is essential for return to tissue homeostasis after acute inflammation, promoting fibrinogenesis and wound healing at injury sites.
Samuele Di Carmine +3 more
openaire +3 more sources
CDX2 regulates interleukin‐33 gene expression in intestinal epithelial cells (LS174T)
FEBS Open Bio, 2021 Dysregulation of interleukin‐33 (IL‐33) has been implicated in the pathogenesis of several autoimmune and inflammatory diseases, but few studies have examined transcriptional regulation of the IL33 gene.
Sylvester Larsen +8 more
doaj +1 more source