Results 61 to 70 of about 2,248,771 (288)

Study of interleukin 33 in rheumatoid arthritis versus osteoarthritis patients

Egyptian Rheumatology and Rehabilitation, 2017
Aim of the work To compare the expression of serum interleukin 33 (IL33), a new member of the interleukin1 (IL-1) cytokine family, in rheumatoid arthritis (RA) versus osteoarthritis (OA) patients and to correlate it with clinical, laboratory and ...
Aliaa M. Abd El-Aziz Farag, Nagat M El-Gazzar, Marwa A.Abo El Hawa, Mohamed A.Saad Attia   +3 more
doaj   +1 more source

Interleukin-33 (IL-33) as a Diagnostic and Prognostic Factor in Traumatic Brain Injury

, 2020
Interleukin-33 (IL-33) is a cytokine involved in interleukin-1 family. Role of IL-33 in immune system activation is well described in the literature. IL-33 has been identified as an endogenous alarm signal (alarmin) to alert various types of immune cells
Ali Kemal Erenler, Ahmet Baydin
core   +1 more source

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

FEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

Therapeutic Strategies for Targeting IL-33/ST2 Signalling for the Treatment of Inflammatory Diseases

Cellular Physiology and Biochemistry, 2018
Interleukin (IL)-33, a member of the IL-1 family of cytokines, is involved in innate and adaptive immune responses via interaction with its receptor, ST2.
Wei-Yu Chen, Tzu-Hsien Tsai, Jenq-Lin Yang, Lung-Chih Li   +3 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Anacardic acid, interleukin-33, and the quest for remyelination [PDF]

Proceedings of the National Academy of Sciences, 2020
In PNAS, Ljunggren-Rose et al. (1) present results from a study assessing the effect of anacardic acid, a salicylic acid derivative with a 15- or 17-carbon-containing alkyl chain substituent (i.e., 2-hydroxy 6-alkylbenzoic acid), on remyelination. Anacardic acids are phytochemicals that are found in foods such as cashews and mangoes.
openaire   +2 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Interplay Between the IL-33/ST2 Axis and Bone Marrow ILC2s in Protease Allergen-Induced IL-5-Dependent Eosinophilia

Frontiers in Immunology, 2020
Background: Eosinophils develop from CD34+ progenitor cells in the bone marrow under the influence of interleukin (IL)-5. Several cell types produce IL-5, including type 2 innate lymphoid cells (ILC2s).
Emma Boberg, Kristina Johansson, Carina Malmhäll, Jenny Calvén, Julie Weidner, Madeleine Rådinger   +5 more
doaj   +1 more source

Interleukin-33 from Monocytes Recruited to the Lung Contributes to House Dust Mite-Induced Airway Inflammation in a Mouse Model. [PDF]

, 2016
Interleukin-33 (IL-33) activates group 2 innate lymphoid cells (ILC2), resulting in T-helper-2 inflammation in bronchial asthma. Airway epithelial cells were reported as sources of IL-33 during apoptosis and necrosis.
Keigo Kurata (2838713), Hiroki Tashiro (2838710), Naoko Sueoka-Aragane (402105), Hiroki Tashiro, Go Kato, Shinichiro Hayashi, Shinya Kimura (247648), Keigo Kurata, Go Kato (285665), Shinichiro Hayashi (2838707), Koichiro Takahashi, Shinya Kimura, Naoko Sueoka-Aragane, Koichiro Takahashi (2838716)   +13 more
core   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source