Results 51 to 60 of about 445,727 (296)

Association between interleukin‑33 and ovarian cancer

Oncology Reports, 2018
Ovarian cancer is the leading cause of cancer‑ associated mortality in the female reproductive system. Interleukin (IL)‑33 and its receptor IL 1 receptor like 1 (also termed ST2) are expressed by many cell types including epithelial cells. The role of IL‑33 in the pathogenesis of neoplasia remains controversial. The authors previously demonstrated that
Xiaoqing, Liu, Dwayne M, Hansen, Noah J, Timko, Ziwen, Zhu, Andrew, Ames, Chenglu, Qin, Michael B, Nicholl, Qian, Bai, Xuhui, Chen, Mark R, Wakefield, Gage, West, Yujiang, Fang   +11 more
openaire   +3 more sources

Interleukin-33 produced by M2 macrophages and other immune cells contributes to Th2 immune reaction of IgG4-related disease [PDF]

, 2017
IgG4-related disease (IgG4-RD) is characterized by elevated serum IgG4 and marked infiltration of IgG4-positive cells in multiple organs. Interleukin-33 (IL-33) is a recently described cytokine that is secreted by damaged epithelial cells, macrophages ...
Furukawa Sachiko, Hayashida Jun-Nosuke, Iizuka-Koga Mana, Ishiguro Noriko, Maehara Takashi, Miyake Kensuke, Moriyama Masafumi, Nakamura Seiji, Nakashima Hitoshi, Sumida Takayuki, Tanaka Akihiko, Tsuboi Hiroto, Yamauchi Masaki, 住田 孝之, 坪井 洋人   +14 more
core   +1 more source

Role of interleukin 33 in chronic rhinosinusitis [PDF]

Thorax, 2017
Chronic rhinosinusitis (CRS) is a heterogenous airways disease characterised by inflammation of the upper airways and sinuses that persists for at least 12 weeks. CRS is frequently divided into two endotypes based on the presence or absence of nasal polyps (NPs): CRS with NPs (CRSwNP) and CRS without NPs (CRSsNP).
openaire   +2 more sources

Study of interleukin 33 in rheumatoid arthritis versus osteoarthritis patients

Egyptian Rheumatology and Rehabilitation, 2017
Aim of the work To compare the expression of serum interleukin 33 (IL33), a new member of the interleukin1 (IL-1) cytokine family, in rheumatoid arthritis (RA) versus osteoarthritis (OA) patients and to correlate it with clinical, laboratory and ...
Aliaa M. Abd El-Aziz Farag, Nagat M El-Gazzar, Marwa A.Abo El Hawa, Mohamed A.Saad Attia   +3 more
doaj   +1 more source

Red Blood Cells Store and Release Interleukin-33 [PDF]

Journal of Investigative Medicine, 2015
Interleukin-33 (IL-33) is a member of the IL-1 cytokine superfamily that potently drives production of a variety of cytokines and contributes to the pathogenesis of inflammatory diseases. The IL-33 is a nuclear protein and is released from apoptotic or necrotic cells.
Jianxin, Wei, Jing, Zhao, Valerie, Schrott, Yingze, Zhang, Mark, Gladwin, Grant, Bullock, Yutong, Zhao   +6 more
openaire   +2 more sources

Therapeutic Strategies for Targeting IL-33/ST2 Signalling for the Treatment of Inflammatory Diseases

Cellular Physiology and Biochemistry, 2018
Interleukin (IL)-33, a member of the IL-1 family of cytokines, is involved in innate and adaptive immune responses via interaction with its receptor, ST2.
Wei-Yu Chen, Tzu-Hsien Tsai, Jenq-Lin Yang, Lung-Chih Li   +3 more
doaj   +1 more source

Interleukin-33 and ST2 Signaling in Tumor Microenvironment [PDF]

Journal of Interferon & Cytokine Research, 2019
Interleukin-33 (IL-33) is one of the members of the IL-1 family of cytokines and a ligand of ST2 and IL-1 receptor accessory protein (IL-1RAcP) that is known to affect Th2 inflammatory response with partial effects on Th1 responses. This cytokine is released by epithelial and smooth muscle cells of the airway system during their injury by several ...
Jaewoo, Hong, Soohyun, Kim, P Charles, Lin   +2 more
openaire   +2 more sources

Two Faces of NOTCH1 in Childhood Lymphoblastic T‐Cell Neoplasia: Prognostic Divergence of Mutational and Structural Aberrations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider, Amelie Alfert, Marc Hotfilder, Birgit Burkardt, Marcel te Vrugt   +4 more
wiley   +1 more source

Association between pro-inflammatory cytokine interleukin-33 and periodontal disease in the elderly: A retrospective study

Journal of Indian Society of Periodontology, 2017
Background: Senescence is a multifactorial process that in humans may be accompanied by inflammation and immune dysfunction in the oral cavity. Notably, periodontal disease, considered one of the most common inflammatory disorders in the oral cavity, has
Wellington Francisco Rodrigues, Camila Botelho Miguel, Niege Silva Mendes, Carlo José Freire Oliveira, Carlos Ueira-Vieira   +4 more
doaj   +1 more source

Comparation between serum levels of interleukin-33 in children with allergic asthma before and after inhalatory corticosteroid treatment [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2020
Introduction/Objective. Interleukin 33 (IL-33) has a very significant function in inflammatory and autoimmune mechanisms, but its significance in immunopathogenic mechanisms of different allergic diseases, including allergic asthma (AA), is becoming ...
Milanović Borko, Vijatov-Đurić Gordana, Stojčević-Maletić Jelena, Stojanović Vesna   +3 more
doaj   +1 more source