Results 11 to 20 of about 2,248,771 (288)
Hippocampal interleukin-33 mediates neuroinflammation-induced cognitive impairments
Journal of Neuroinflammation, 2020 Background Interleukin (IL)-33 is expressed in a healthy brain and plays a pivotal role in several neuropathologies, as protective or contributing to the development of cerebral diseases associated with cognitive impairments.
Flora Reverchon +8 more
doaj +2 more sources
Emerging role of interleukin‐33 in autoimmune diseases
Immunology, 2013 SummaryInterleukin‐33 (IL‐33) is a member of the IL‐1 cytokine family. It predominantly induces type 2 immune responses and thus is protective against atherosclerosis and nematode infections but contributes to allergic airway inflammation. Interleukin‐33 also plays a pivotal role in the development of many autoimmune diseases through mechanisms that ...
Cheng, Pei +5 more
openaire +4 more sources
Impact of angiotensin converting enzyme inhibition on post- coronary artery bypass interleukin 6 release [PDF]
, 2002 Background: Angiotensin 1 converting enzyme (ACE) inhibitors reduce morbidity and mortality after coronary artery bypass graft surgery (CABG). This benefit may result from an anti- inflammatory action.
Humphries, S.E. +5 more
core +8 more sources
Interleukin-33: Its Emerging Role in Allergic Diseases
Molecules, 2018 Allergic diseases, which include asthma, allergic rhinitis (AR), chronic rhinosinusitis (CRS), atopic dermatitis (AD), food allergy (FA), allergic keratoconjunctivitis, seriously affect the quality of life of people all over the world.
Wen Ding +5 more
doaj +2 more sources
Interleukin‐33 in allergy [PDF]
Allergy, 2012 AbstractInterleukin‐33 (IL‐33) is a member of the IL‐1 cytokine family, which includes IL‐1 and IL‐18, and is considered to be important for host defense against nematodes by inducing Th2 cytokine production via the IL‐33 receptor. IL‐33 receptor is a heterodimer of IL‐1 receptor‐like 1 (IL‐1RL1; also called ST2, T1, Der4, and fit‐1) and IL‐1 receptor ...
Tatsukuni, Ohno +4 more
openaire +2 more sources
Interleukin 33: a suitable target for biological therapies of COPD? [PDF]
ERJ Open ResearchCorrado Pelaia
doaj +2 more sources
Interleukin-33 in the human placenta [PDF]
The Journal of Maternal-Fetal & Neonatal Medicine, 2012 Interleukin-33 (IL-33) is the newest member of the IL-1 cytokine family, a group of key regulators of inflammation. The purpose of this study was to determine whether IL-33 is expressed in the human placenta and to investigate its expression in the context of acute and chronic chorioamnionitis.Placental tissues were obtained from five groups of ...
Vanessa, Topping +10 more
openaire +2 more sources
The role of interleukin-33 in organ fibrosis
Discovery Immunology, 2022 Summary Interleukin (IL)-33 is highly expressed in the nucleus of cells present at barrier sites and signals via the ST2 receptor. IL-33 signalling via ST2 is essential for return to tissue homeostasis after acute inflammation, promoting fibrinogenesis and wound healing at injury sites.
Samuele Di Carmine +3 more
openaire +3 more sources
The Role of Interleukin-33 in Rhinitis [PDF]
Current Allergy and Asthma Reports, 2013 IL-33, a member of the IL-1 cytokine family and a ligand to receptor ST2, has great potential to induce a T helper 2-type inflammatory response. IL-33 is proven to be released by epithelial cells during their injury by different environmental stimuli such as airborne allergens, viruses, and air pollutants. IL-33 acting as an endogenous danger signal is
Rogala, Barbara, Glück, Joanna
openaire +2 more sources
The role of interleukin-33 in chronic rhinosinusitis [PDF]
Thorax, 2016 Interleukin (IL)-33, a new member of the IL-1 family, is constitutively expressed in epithelial tissues and lymphoid organs and plays an important role in the pathogenesis of allergic disease. However, the role of IL-33 in chronic rhinosinusitis with nasal polyps (CRSwNP) remains unclear.To investigate the role of IL-33 in the pathophysiology of CRSwNP.
Dong-Kyu, Kim +7 more
openaire +2 more sources