Results 11 to 20 of about 449,109 (258)
Interleukin-33 in the human placenta [PDF]
The Journal of Maternal-Fetal & Neonatal Medicine, 2012 Interleukin-33 (IL-33) is the newest member of the IL-1 cytokine family, a group of key regulators of inflammation. The purpose of this study was to determine whether IL-33 is expressed in the human placenta and to investigate its expression in the context of acute and chronic chorioamnionitis.Placental tissues were obtained from five groups of ...
Vanessa, Topping +10 more
openaire +2 more sources
Hippocampal interleukin-33 mediates neuroinflammation-induced cognitive impairments
Journal of Neuroinflammation, 2020 Background Interleukin (IL)-33 is expressed in a healthy brain and plays a pivotal role in several neuropathologies, as protective or contributing to the development of cerebral diseases associated with cognitive impairments.
Flora Reverchon +8 more
doaj +1 more source
The Role of Interleukin-33 in Rhinitis [PDF]
Current Allergy and Asthma Reports, 2013 IL-33, a member of the IL-1 cytokine family and a ligand to receptor ST2, has great potential to induce a T helper 2-type inflammatory response. IL-33 is proven to be released by epithelial cells during their injury by different environmental stimuli such as airborne allergens, viruses, and air pollutants. IL-33 acting as an endogenous danger signal is
Rogala, Barbara, Glück, Joanna
openaire +2 more sources
The role of interleukin-33 in organ fibrosis
Discovery Immunology, 2022 Summary Interleukin (IL)-33 is highly expressed in the nucleus of cells present at barrier sites and signals via the ST2 receptor. IL-33 signalling via ST2 is essential for return to tissue homeostasis after acute inflammation, promoting fibrinogenesis and wound healing at injury sites.
Samuele Di Carmine +3 more
openaire +3 more sources
The role of interleukin-33 in chronic rhinosinusitis [PDF]
Thorax, 2016 Interleukin (IL)-33, a new member of the IL-1 family, is constitutively expressed in epithelial tissues and lymphoid organs and plays an important role in the pathogenesis of allergic disease. However, the role of IL-33 in chronic rhinosinusitis with nasal polyps (CRSwNP) remains unclear.To investigate the role of IL-33 in the pathophysiology of CRSwNP.
Dong-Kyu, Kim +7 more
openaire +2 more sources
Interleukin-33 modulates inflammation in endometriosis [PDF]
Scientific Reports, 2017 AbstractEndometriosis is a debilitating condition that is categorized by the abnormal growth of endometrial tissue outside the uterus. Although the pathogenesis of this disease remains unknown, it is well established that endometriosis patients exhibit immune dysfunction.
Miller, Jessica E. +8 more
openaire +2 more sources
INTERLEUKIN 33 AND FIBROSIS: PATHOGENESIS UPDATED
Медицинская иммунология, 2018 Interleukin 33 (IL-33) is a member of the IL-1 family, which is widely expressed on all types of cells. IL-33 was identified as a functional ligand for the plasma membrane receptor complex, which is a heterodimer consisting of a membrane bound ST2 ...
E. G. Uchasova +3 more
doaj +1 more source
Interleukin 33: a switch-hitting cytokine [PDF]
Current Opinion in Immunology, 2014 For many years IL-33 has been widely studied in the context of T helper type 2 (Th2)-driven inflammatory disorders. Interestingly, IL-33 has now emerged as a cytokine with a plethora of pleiotropic properties. Depending on the immune cells targeted by IL-33, it is reported to not only promote Th2 immunity, but also to induce T helper type 1 (Th1 ...
Daniel O, Villarreal, David B, Weiner
openaire +2 more sources
The enigmatic processing and secretion of interleukin-33 [PDF]
Cellular & Molecular Immunology, 2010 Interleukin-33 (IL-33) is the most attractive novel cytokine identified as an IL-1 family member. IL-33 was first named NF-HEV (nuclear factor from high endothelial venules), as it was known to interact with nuclear chromatin although its exact intracellular functions are still to be clarified.
Weihua, Zhao, Zhiqing, Hu
openaire +2 more sources
Full Length Interleukin 33 Aggravates Radiation-Induced Skin Reaction
Frontiers in Immunology, 2017 The interleukin (IL)-1 family member IL-33 has been described as intracellular alarmin with broad roles in wound healing, skin inflammation but also autoimmunity.
Olga Kurow +13 more
doaj +1 more source