Results 11 to 20 of about 445,727 (296)
Interleukin-33 regulates the functional state of microglia
Frontiers in Cellular Neuroscience, 2022 Microglia, the most prominent resident immune cells, exhibit multiple functional states beyond their immunomodulatory roles. Non-immune functions such as synaptic reorganization, removal of cellular debris, and deposition of abnormal substances are ...
Tianqing Xiong +5 more
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Interleukin-33 in cutaneous wound healing
European Journal of InflammationBarrier tissues like the skin, gastrointestinal tract, and respiratory system exhibit high IL-33 expression. IL-33 expression increases in humans and mice during cutaneous wound healing.
Bei Liu
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Interleukin-33: Its Emerging Role in Allergic Diseases [PDF]
Molecules, 2018 Allergic diseases, which include asthma, allergic rhinitis (AR), chronic rhinosinusitis (CRS), atopic dermatitis (AD), food allergy (FA), allergic keratoconjunctivitis, seriously affect the quality of life of people all over the world.
Wen Ding +5 more
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Higher interleukin-33 levels in aggressive periodontitis cases
Journal of Indian Society of Periodontology, 2019 Context: Interleukin-33 (IL-33) is a novel alarmin that warns immune cells of tissue destruction in injury or infection. Aims: This study is aimed at analyzing and correlating the concentration of IL-33 in the gingival crevicular fluid (GCF) and plasma ...
Sujatha Pai Ballambettu +3 more
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Interleukin-33 in Systemic Sclerosis: Expression and Pathogenesis
Frontiers in Immunology, 2018 Interleukin-33 (IL-33), a member of the IL-1 superfamily, functions as a traditional cytokine and nuclear factor. It is proposed to have an “alarmin” role. IL-33 mediates biological effects by interacting with the ST2 receptor and IL-1 receptor accessory
Liya Li +5 more
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Interleukin‐33 in allergy [PDF]
Allergy, 2012 AbstractInterleukin‐33 (IL‐33) is a member of the IL‐1 cytokine family, which includes IL‐1 and IL‐18, and is considered to be important for host defense against nematodes by inducing Th2 cytokine production via the IL‐33 receptor. IL‐33 receptor is a heterodimer of IL‐1 receptor‐like 1 (IL‐1RL1; also called ST2, T1, Der4, and fit‐1) and IL‐1 receptor ...
Tatsukuni, Ohno +4 more
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Interleukin-33 in the human placenta [PDF]
The Journal of Maternal-Fetal & Neonatal Medicine, 2012 Interleukin-33 (IL-33) is the newest member of the IL-1 cytokine family, a group of key regulators of inflammation. The purpose of this study was to determine whether IL-33 is expressed in the human placenta and to investigate its expression in the context of acute and chronic chorioamnionitis.Placental tissues were obtained from five groups of ...
Vanessa, Topping +10 more
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Interleukin-33 modulates inflammation in endometriosis [PDF]
Scientific Reports, 2017 AbstractEndometriosis is a debilitating condition that is categorized by the abnormal growth of endometrial tissue outside the uterus. Although the pathogenesis of this disease remains unknown, it is well established that endometriosis patients exhibit immune dysfunction.
Miller, Jessica E. +8 more
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Interleukin 33: a switch-hitting cytokine [PDF]
Current Opinion in Immunology, 2014 For many years IL-33 has been widely studied in the context of T helper type 2 (Th2)-driven inflammatory disorders. Interestingly, IL-33 has now emerged as a cytokine with a plethora of pleiotropic properties. Depending on the immune cells targeted by IL-33, it is reported to not only promote Th2 immunity, but also to induce T helper type 1 (Th1 ...
Daniel O, Villarreal, David B, Weiner
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Behavioral Changes in Mice Lacking Interleukin-33 [PDF]
eneuro, 2017 AbstractInterleukin (IL)-33 is a member of the IL-1 family of cytokines. IL-33 is expressed in nuclei and secreted as alarmin upon cellular damage to deliver a danger signal to the surrounding cells. Previous studies showed that IL-33 is expressed in the brain and that it is involved in neuroinflammatory and neurodegenerative processes in both humans ...
Eisuke Dohi +6 more
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