Results 41 to 50 of about 2,108,740 (316)

Replicating viral vector platform exploits alarmin signals for potent CD8⁺ T cell-mediated tumour immunotherapy. [PDF]

, 2017
Viral infections lead to alarmin release and elicit potent cytotoxic effector T lymphocyte (CTL ^eff ) responses. Conversely, the induction of protective tumour-specific CTL ^eff and their recruitment into the
A Hyvarinen, A Plyusnin, A Wortmann, AM Henao-Restrepo, C Baumann, C Butts, CA Klebanoff, CB Stephensen, D Peng, D Valmori, D Zamarin, DA Enria, DK Reichenbach, DL Popkin, E Scandella, ER Chare, F Duan, F Pages, F Spertini, GP Dunn, HE Webb, J Delaloye, J Liu, J Zhu, JA Joyce, JF Vansteenkiste, JY Liu, K Oboki, KM Quinn, L Flatz, L Flatz, L Flatz, L Zhang, LC Anton, M Lewandoski, M Peine, M Perez, M Suter, M Vanneman, MD Stenglein, MF Callan, MF Kotturi, MJ Townsend, N Fasnacht, O Kew, P Grob, P Sharma, PC Doherty, PC Tumeh, PW Kantoff, R Schirmbeck, R Sommerstein, RH Andtbacka, RM Zinkernagel, RM Zinkernagel, S Darbre, S Spranger, SA Fuertes Marraco, SA Rosenberg, SF Emonet, SG Hansen, SN Mueller, T Querec, TF Gajewski, TN Schumacher, WV Bonilla, WV Bonilla, X de Lamballerie, Y Iwai, Z Waibler   +69 more
core   +2 more sources

IL-33 in Mental Disorders

Medicina, 2021
Mental disorders are common in the general population; every year about 25% of the total European population is affected by a mental condition. The prevalence of psychiatric disorders might be underestimated.
Gianluca Pandolfo, Giovanni Genovese, Marco Casciaro, Maria Rosaria Anna Muscatello, Antonio Bruno, Giovanni Pioggia, Sebastiano Gangemi   +6 more
doaj   +1 more source

Replicating viral vector platform exploits alarmin signals for potent CD8+ T cell-mediated tumour immunotherapy [PDF]

, 2017
Viral infections lead to alarmin release and elicit potent cytotoxic effector T lymphocyte (CTLeff) responses. Conversely, the induction of protective tumour-specific CTLeff and their recruitment into the tumour remain challenging tasks.
Bonilla, Weldy V., Darbre, Stephanie, Kallert, Sandra M., Kreutzfeldt, Mario, Kreuzaler, Matthi, Loehning, Max, Mueller, Philipp, Page, Nicolas   +7 more
core   +1 more source

Comparison of Interleukin-33 serum levels in asthmatic patients with a control group and relation with the severity of the disease

International Journal of Preventive Medicine, 2017
Background: The relation between interleukin-33 (IL-33) and asthma is not precisely known yet. The present study set to compare the serum level of IL-33 in patients with asthma and controls and study the relation with the severity of disease.
Tooba Momen, Hamid Ahanchian, Mohsen Reisi, Seyedeh Azra Shamsdin, Armindokht Shahsanai, Majid Keivanfar   +5 more
doaj   +1 more source

Interleukin-33 Amplifies Human Mast Cell Activities Induced by Complement Anaphylatoxins

Frontiers in Immunology, 2021
Both, aberrant mast cell responses and complement activation contribute to allergic diseases. Since mast cells are highly responsive to C3a and C5a, while Interleukin-33 (IL-33) is a potent mast cell activator, we hypothesized that IL-33 critically ...
Peter W West, R. Bahri, Karen M Garcia-Rodriguez, Georgia Sweetland, Georgia Wileman, R. Shah, A. Montero, L. Rapley, S. Bulfone-Paus   +8 more
semanticscholar   +1 more source

Interleukin-33 in human gliomas: Expression and prognostic significance [PDF]

, 2016
Interleukin-33 (IL-33) is a nuclear and pleiotropic cytokine with regard to its cellular sources and its actions. IL-33 is involved in the pathogenesis of brain diseases.
Cathomas, Gieri, Frei, Karl, Gramatzki, Dorothee, Mertz, Kirsten Diana, Moch, Holger, Weller, Michael   +5 more
core   +1 more source

Interleukin-33 Primes Mast Cells for Activation by IgG Immune Complexes [PDF]

, 2012
Mast cells (MCs) are heterogeneous cells whose phenotype is modulated by signals received from the local microenvironment. Recent studies have identified the mesenchymal-derived cytokine IL-33 as a potent direct activator of MCs, as well as regulator of ...
Fishgal, Nadia, Hei, Hillary, Kaieda, Shinjiro, Lee, Richard Theodore, Nigrovic, Peter Andrija, Shnayder, Ruslan, Stevens, Richard Leslie, Wang, Jun-Xia   +7 more
core   +2 more sources

Interleukin-33 Potentiates Bleomycin-Induced Lung Injury [PDF]

American Journal of Respiratory Cell and Molecular Biology, 2013
The mechanisms of interstitial lung disease (ILD) remain incompletely understood, although recent observations have suggested an important contribution by IL-33. Substantial elevations in IL-33 expression were found in the lungs of patients with idiopathic pulmonary fibrosis and scleroderma lung disease, as well as in the bleomycin injury mouse model ...
Irina G, Luzina, Pavel, Kopach, Virginia, Lockatell, Phillip H, Kang, Ashish, Nagarsekar, Allen P, Burke, Jeffrey D, Hasday, Nevins W, Todd, Sergei P, Atamas   +8 more
openaire   +2 more sources

Neonatal malnutrition and macrophage in Candida albicans infection [PDF]

Brazilian Journal of Biology
Neonatal malnutrition is an important environmental exposure factor that can influence the development and health of all body systems, including the immune system.
N. G. Morais-Coneglian, T. B. Costa, V. R. A. Pereira, M. P. Cavalcanti, N. N. G. Morais, A. O. Souza, C. M. M. B. Castro   +6 more
doaj   +1 more source

The serum levels and clinical significance of interleukin-33 and soluble ST2 in patients with vitiligo

Pifu-xingbing zhenliaoxue zazhi, 2020
Objective: To investigate the clinical significance of interleukin-33(IL-33) and soluble ST2 (sST2) in patients with vitiligo. Methods: The serum concentrations of IL-33 and sST2 were determined by enzyme linked immunosorbent assay (ELISA) respectively ...
Li YANG, Dong-qing LU, Han MA
doaj   +1 more source