Broad proteomic screen reveals shared serum proteomic signature in patients with psoriatic arthritis and psoriasis without arthritis [PDF]
OBJECTIVE: To identify novel serum proteins involved in the pathogenesis of PsA as compared with healthy controls, psoriasis (Pso) and AS, and to explore which proteins best correlated to major clinical features of the disease. METHODS: A high-throughput
Balak, Deepak+12 more
core
PDB: 4ZSF, Interleukin-6 (IL-6) in complex with antibody 68F2 (311K, 38°C, 100 ns)
Razvan Stan
openalex +2 more sources
Time‐Controlled Dual Targeting to Program Systemic and Intercellular Transfer of Therapeutic Effects
Aspirin‐liposomes loaded onto monocytes enable inflammation‐triggered targeting and efficient hand‐over of aspirin to inflamed cells. Monocytes uptake a significant portion of aspirin‐liposomes, prolonging therapeutic action. This approach enhances anti‐inflammatory effects through intercellular transfer, demonstrating a translational strategy for ...
Seung Eun Yu+6 more
wiley +1 more source
Potential roles of IL-38, among other inflammation-related biomarkers, in predicting post-percutaneous coronary intervention cardiovascular events [PDF]
Percutaneous coronary intervention (PCI), as a relatively rapid and effective minimally invasive treatment for coronary heart disease (CHD), can effectively relieve coronary artery stenosis and restore myocardial perfusion.
Bo Dong, Lu Kou, Ning Yang, Qin Qin
core +1 more source
Production and regulation of interleukin-1 family cytokines at the materno-fetal interface [PDF]
IL-1 family members regulate innate immune responses, are produced by gestation-associated tissues, and have a role in healthy and adverse pregnancy outcomes.
Aled H. Bryant+5 more
core +1 more source
P069 Constitutive overexpression of interleukin 38 has a negative impact on human NHK keratinocyte fitness [PDF]
Loïc Mermoud+4 more
openalex +1 more source
PDB: 5FB8, Interleukin-16 bound to mAb 14.1 (311K, 38°C, 100 ns)
Razvan Stan
openalex +2 more sources
The MPTT‐nanozyme‐hydrogel system (Mn3O4@ChS‐HA) provides a multifunctional therapeutic strategy for intervertebral disc degeneration (IVDD), effectively targeting oxidative stress and enhancing AF repair by restoring extracellular matrix (ECM) and redox homeostasis.
Yangyang Chen+13 more
wiley +1 more source
This study investigates the causal associations between interleukin receptor-related factors and the development of endometriosis, as their etiology and pathophysiology remain largely unknown.
Si-Ji Lv+3 more
doaj +1 more source
Interleukin-33 in Malignancies: Friends or Foes? [PDF]
The human Interleukin-33 (IL-33), a member of the IL-1 family, is the cytokine as a cell endogenous alarmin, released by damaged or necrotic barrier cells (endothelial and epithelial cells).
Guo-Jun Zhang+5 more
core +1 more source