Results 241 to 250 of about 1,628,367 (268)

Combinatorial treatment with upadacitinib abrogates systemic toxicity of a tumor-targeted IL-2 fusion protein. [PDF]

J Immunother Cancer
Rotta G, Prodi E, Seehusen F, Bocci M, Prisco F, Gilardoni E, Comacchio C, Halin C, Puca E, Neri D, Dakhel Plaza S.   +10 more
europepmc   +1 more source

Retraction Note: The role of cyclooxygenase-2, interleukin-1β and fibroblast growth factor-2 in the activation of matrix metalloproteinase-1 in sheared-chondrocytes and articular cartilage. [PDF]

Sci Rep
Guan PP, Guo JW, XinYu, Wang Y, Wang T, Konstantopoulos K, Wang ZY, Wang P.   +7 more
europepmc   +1 more source

Levels of IL-1β, MMP-8, and MMP-9 in the Saliva of Subjects With Periodontitis: A Systematic Review and Meta-Analysis. [PDF]

J Clin Lab Anal
Alarcón-Sánchez MA, Rodríguez-Montaño R, Mosaddad SA, Heboyan A.   +3 more
europepmc   +1 more source

Pathophysiology of COVID-19: A Post Hoc Analysis of the ICAT-COVID Clinical Trial of the Bradykinin Antagonist Icatibant. [PDF]

Pathogens
Malchair P, Giol J, Jacob J, Villoria J, Carnaval T, Videla S.   +5 more
europepmc   +1 more source

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Interleukin-38 and insulin resistance.

Endocrine, Metabolic & Immune Disorders - Drug Targets, 2023
Insulin resistance, i.e., decreased biological response to insulin, is a risk factor for many diseases, such as obesity, type 2 diabetes (T2DM), cardiovascular disease, polycystic ovary syndrome, some forms of cancer and neurodegenerative diseases.
Kamil Klejbuk, M. Strączkowski
semanticscholar   +3 more sources

Interleukin-38 in atherosclerosis.

Clinica Chimica Acta, 2022
Chronic inflammation caused by immune cells and their mediators is a characteristic of atherosclerosis. Interleukin-38 (IL-38), a member of the IL-1 family, exerts multiple anti-inflammatory effects via specific ligand-receptor interactions. Upon recognizing a specific receptor, IL-38 restrains mitogen-activated protein kinase (MAPK), nuclear factor ...
Xiao-Hong Zhang, Y. Li, Li Zhou, Guoping Tian   +3 more
semanticscholar   +3 more sources

Biology of interleukin-38 and its role in chronic inflammatory diseases.

International Immunopharmacology, 2021
Interleukin (IL)-38 is the tenth member of the IL-1 cytokine family. IL-38 shares high similarity with IL-36Ra and IL-1Ra and can bind to their receptors, thus exerting an anti-inflammatory effect. Despite the lack of a signal peptide, IL-38 can be released from several cell types, but its maturation process remains obscure.
Hua-song Xia, Yue Liu, Yang Fu, Meng Li, Yan-Qing Wu   +4 more
semanticscholar   +3 more sources

Assessment of the levels of interleukin-17 and interleukin-38 in thyroid-associated ophthalmopathy patients

International Ophthalmology, 2023
The objective of the study was to analyse the levels of IL-17 and IL-38 in the samples of unstimulated tears, orbital adipose tissues, and sera of patients diagnosed with active forms of TAO. The correlation of the levels of IL-17 and IL-38 with clinical activity score (CAS) was scrutinized.A study was conducted at the Kazakhstan Scientific Research ...
Ainur Musakulova, Aigul Balmukhanova, A. Aubakirova, G. Zhunusova, Altynay Balmukhanova, J. Issakhanova, T. Saliev, S. Tanabayeva, Ildar Fakhradiyev   +8 more
semanticscholar   +3 more sources