Results 41 to 50 of about 417,692 (230)

Difference of Maternal Serum Interleukin-8 in Preterm Labor and Full Term Labor

Indonesian Journal of Obstetrics and Gynecology, 2014
Objective: To determine the difference of maternal interleukin-8 (IL-8) in preterm labor and full term labor. Method: This is a cross sectional study with 68 samples, 29 subjects with preterm labor and 39 subjects with full term labor.
Komang W Budiartha, Tjokorda GA Suwardewa   +1 more
doaj   +1 more source

A case report of coronavirus disease‐2019‐induced acute asthma exacerbation in an obese patient

Respirology Case Reports, 2022
The coronavirus disease‐2019 (COVID‐19) has spread worldwide. Previous studies indicated a low prevalence of COVID‐19 induced acute exacerbations of asthma.
Hisashi Sasaki, Jun Miyata, Ai Kobayashi, Shuichi Kawano, Akihiko Kawana   +4 more
doaj   +1 more source

Increased serum interleukin-39 in patients with myasthenia gravis

Abstract Background In 2016, Interleukin-39 (IL-39) was formally acknowledged as a member of the IL-12 cytokine family and identified as a heterodimeric cytokine. It exerts intricate and potentially conflicting functions in the regulation of the immune system, the modulation of inflammatory responses, and the influence on the ...
Kun Jia, Yingzhe Shao, Xuan Liu, Qiuxia Zhang, Li Yang   +4 more
openaire   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Interleukin-39 is a Prognostic Biomarker and Therapy Target for Sepsis. [PDF]

Adv Sci (Weinh)
Sepsis triggers a significant increase in IL‐39 production, with circulating levels markedly elevated and positively correlated with disease severity and poor clinical prognosis in sepsis patients. Mechanistically, macrophage‐derived IL‐39 activates the GP130 signaling pathway via a ligand‐receptor interaction, thereby fueling the pro‐inflammatory ...
Zhang FZ, Liu HJ, Yue Y, Gao JJ, Zhang J, Zhang WW, Zhang YL, Lu WH, Jin SW, Zhang PH.   +9 more
europepmc   +2 more sources

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Targeting the NLRP3 inflammasome in chronic inflammatory diseases: current perspectives

Journal of Inflammation Research, 2015
Ema Ozaki,1 Matthew Campbell,1 Sarah L Doyle2,3 1Department of Genetics, 2Department of Clinical Medicine, School of Medicine, Trinity College Dublin, 3National Children's Research Centre, Our Lady's Children's Hospital Crumlin, Dublin ...
Ozaki E, Campbell M, Doyle SL
doaj  

Association between interleukin-39 (IL-39) with hormonal and metabolic changes in women with polycystic ovarian syndrome

Anaesthesia, Pain & Intensive Care
Background & Objective: The most prevalent endocrine defect affecting women in their reproductive years is called polycystic ovarian syndrome (PCOS). It is strongly correlated to metabolic syndrome, insulin resistance, and an increased risk of diabetes and cardiovascular disease in the future.
Hanaa Addai Ali, Kawther Mejbel Hussein
openaire   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source